liver enzyme Articles
-
Enzymes for Disease Diagnosis: An Overview
Enzymes are protein molecules that catalyze chemical reactions in living organisms. They are involved in many metabolic processes and play a critical role in maintaining the health of the body. In recent years, enzymes have been widely used in disease diagnosis, providing a quick and accurate way to detect and monitor diseases. Enzymes for disease diagnosis can be divided into two categories: ...
-
CBD: Perils, Promise and Development for Neuropathic Pain
Cannabidiol, or CBD, is one of several compounds extracted from the cannabis (marijuana) plant. In recent years, CBD has become enormously popular, and its market is believed to be hundreds of millions of dollars. Believers and users of CBD extoll its benefits for inflammation, muscle soreness, pain, anxiety and a whole host of other things, including cancer. It is, however, very understudied. ...
-
Clinical CRISPR Success Demonstrates Need for Quality Control
The Clinical CRISPR Successes Are Stacking Up. But Where’s the Emphasis on Quality Control? In mid-September, Intellia released some promising data on two of their CRISPR-based therapeutics. These results are a significant milestone for genome editing and validation of its effectiveness in the clinic. However, the safety of CRISPR-based therapeutics has been a major concern and part of a ...
By CRISPR QC
-
Symberix Featured in Nature
Durham, NC (February 3, 2020) - An article in Nature highlights Symberix's efforts to understand the complex relationship between drugs and the microbiome. The paper discusses recent contributions to the emerging field of “pharmacomicrobiomics” -- the study of how microbes impact drug disposition, efficacy, and toxicity. Symberix is developing bacteria-targeted small molecules that ...
-
Expanding Our Commitment to Rare Disease Therapeutics
Each year, the last day of February serves as a reminder to pause and reflect on the challenges and unique needs of patients and families living with rare diseases. It is an opportunity for all members of the patient, medical, and scientific communities to shine a light on the urgent need to improve the care and support for those impacted by such conditions. At Moderna, we are working to ...
-
Tobacco smoke-dependent changes in cytochrome P450 1A1, 1A2, and 2E1 protein expressions in fetuses, newborns, pregnant rats, and human placenta
Tobacco smoke (TS) was described as a mixture of numerous cytochrome P450 (P450) substrates, inducers, and inhibitors. These inducers and inhibitors may modify drug clearance and xenobiotic or endogenous metabolism affecting P450s expression. In the present study, the effect of gestation and TS on: (1) cytochrome P450 CYP1A1, CYP1A2, and CYP2E1 protein expressions, and (2) cytochrome P450-linked ...
-
The Pivotal Glutathione Reductase
Glutathione is a tripeptide containing sulfhydryl groups combined with glutamic acid, cysteine and glycine. Glutathione has two forms, reduced (G-SH) and oxidized (G-S-S-G), and reduced glutathione accounts for the vast majority under physiological conditions. Glutathione reductase catalyzes the interconversion between the two types. The coenzyme of this enzyme is NADPH provided by the ...
-
The Function and Application of the Magic Superoxide Dismutase
Some substances can easily interact with the oxygen in the air when exposed to the air, causing chemical changes in the substance. This is the process of oxidation. Sun exposure, air pollution, radiation, etc. will cause the human skin to produce a large amount of superoxide free radicals, and its strong oxidizing ability will accelerate the speed of skin oxidation, and may even cause serious ...
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you