Liver Enzyme Articles & Analysis
4 articles found
Metabolism involves the chemical alterations made to the drug by the body, primarily through liver enzymes. Investigating metabolic pathways is vital for predicting how long a drug will remain active and how its safety profile may change as it is processed by the body. ...
Enzymes that are specific to the disease itself are often used to diagnose and monitor cancer, heart disease, and liver disease. ...
The Clinical CRISPR Successes Are Stacking Up. But Where’s the Emphasis on Quality Control? In mid-September, Intellia released some promising data on two of their CRISPR-based therapeutics. These results are a significant milestone for genome editing and validation of its effectiveness in the clinic. However, the safety of CRISPR-based therapeutics has been a major concern and part of a ...
There were several enzymes that were elevated that were indicative of liver toxicity. That was one red flag that came ...