liver heart Articles
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Subacute toxicity of selenium sources in mice
Sixteen groups of mice were fed diets containing different selenium species to compare their toxicity. Inorganic sodium selenate and sodium hydroselenite, elementary nanoSe, organic Sel‐Plex, and Lacto‐MicroSelenium were administered for 14 d at concentrations of 0.5, 5, and 50 ppm Se, equivalent to 0.5, 5, and 50 mg Se/kg food, corresponding to an estimated 4, 40, and 400 µg/kg bw/d Se uptake, ...
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Understanding Induced Pluripotent Stem Cell Differentiation and the Role of iPSC Differentiation Kits in Biological Research
Pluripotent stem cells — cells with the ability to differentiate into nearly any cell type in the body, constituting a significant potential for regenerative medicine. Among these, induced Pluripotent Stem Cells (iPSCs), in particular, have garnered substantial interest from the scientific community due to their ability to be produced from adult cells, eliminating the ethical quandaries ...
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What Are the Applications of Enzymes in Disease Research and Treatment?
With the development of biotechnology in the modern information age, the research, development and utilization of enzymes have become more and more in-depth, and correspondingly, the application of enzymes in medicine has become more and more extensive. 1. The relationship between enzymes and certain diseases The diseases caused by the lack of enzymes in the human body are mostly congenital or ...
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The Functions and Roles of Enzymes
Catalysis Enzymes are a class of biological catalysts. They govern many catalytic processes such as metabolism, nutrition, and energy conversion of organisms. Most of the reactions closely related to life processes are enzyme-catalyzed reactions. These properties of the enzyme enable the intricate process of material metabolism in the cell to proceed in an orderly manner, and to adapt material ...
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What is Sepsis? Key Symptoms, Potential Complications, and Vital Treatment
The term sepsis describes the body's extreme response to infection. When a person suffers from sepsis, his or her immune system has been triggered in response to an infection, which causes inflammation and damages tissues in the body. Symptoms of Sepsis The symptoms of sepsis may include: Fever (102 degrees Fahrenheit or higher) Chills Rapid breathing (above 20 breaths per minute) or ...
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Injecting mRNA and generating CAR-T directly in the body to repair the heart in one shot
January 6, 2022—Researchers at the Perelman School of Medicine at the University of Pennsylvania published a research paper in Science titled: CAR-T cells produced in vivo to treat cardiac injury. Heart damage or inflammation can induce fibroblasts to overproduce fibrous material, causing cardiac fibrosis, which hardens the heart muscle and impairs heart function. Heart failure, liver ...
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Molecular biology of autoinflammatory diseases
The lengthy battle between people and varied bodily, chemical, and organic insults that trigger cell damage (e.g., merchandise of tissue harm, metabolites, and/or infections) have led to the evolution of assorted adaptive responses. These responses are triggered by recognition of damage-associated molecular patterns (DAMPs) and/or pathogen-associated molecular patterns (PAMPs), normally by cells ...
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Mercury and selenium concentrations in skeletal muscle, liver and regions of the heart and kidney in bearded seals from Alaska
Mean concentrations of total mercury [THg] and selenium [TSe] (mass and molar based) were determined for five regions of the heart and two regions of the kidney of bearded seals (Erignathus barbatus) harvested in Alaska in 2010–2011. Mean [THg] and [TSe] of bearded seal liver and skeletal muscle tissues were used for intertissular comparison. Se:Hg molar ratios were used to investigate ...
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Tobacco smoke-dependent changes in cytochrome P450 1A1, 1A2, and 2E1 protein expressions in fetuses, newborns, pregnant rats, and human placenta
Tobacco smoke (TS) was described as a mixture of numerous cytochrome P450 (P450) substrates, inducers, and inhibitors. These inducers and inhibitors may modify drug clearance and xenobiotic or endogenous metabolism affecting P450s expression. In the present study, the effect of gestation and TS on: (1) cytochrome P450 CYP1A1, CYP1A2, and CYP2E1 protein expressions, and (2) cytochrome P450-linked ...
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Avail The Best Treatment of Liver Transplant in Delhi
The liver is one of the most vital organs of the body. It means one cannot live without the proper functioning of the liver. It performs many critical functions of the body which include enhancing metabolism of the body, removing degrading products, and synthesis of enzymes and proteins. The main function of the liver is that the blood enters the liver through two chains – one is the ...
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Bio-Ink: Printing the Future of Medicine and Beyond
Bio-ink is a revolutionary material that is rapidly changing the fields of medicine, tissue engineering, and even bioprinting food. This fascinating substance is essentially a type of ink made from living cells and other biocompatible materials that can be used to 3D print complex biological structures. What is Bio-Ink Made Of? The composition of bio-ink can vary depending on the desired ...
By Matexcel
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Enzymes for Disease Diagnosis: An Overview
Enzymes are protein molecules that catalyze chemical reactions in living organisms. They are involved in many metabolic processes and play a critical role in maintaining the health of the body. In recent years, enzymes have been widely used in disease diagnosis, providing a quick and accurate way to detect and monitor diseases. Enzymes for disease diagnosis can be divided into two categories: ...
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Organoid Models of SARS-CoV-2 Infection learned from COVID-19
The clinical presentation of COVID-19-related illness ranges from asymptomatic to mild respiratory symptoms resembling influenza infection to acute symptoms including pneumonia requiring hospitalization and admission to the intensive care unit. COVID-19 starts in the upper airways and lungs, but in severe cases can also affect the heart, blood vessels, brain, liver, kidneys, and intestines. ...
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What is the difference between infection and disease?
Disease-causing microbes are often found in the human microbiome. So, when does the presence of pathogenic microbes indicate an infection? And when does the presence of infection explain disease? What is an infection? What is a disease? A disease associated with microbes is the outcome of interaction(s) between a microbe(s) and its host in which the host suffers some sort of damage. ...
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Foundational Supplement Program with Whole Food AstaPure® Arava
One of the most pressing questions consumers have is, "What supplements do I need to take daily?" The answer should be simple, start with a strong foundation. Just as if you were building a home, you would first pour a strong foundation in which to build on. The same holds with taking dietary supplements. The four areas of supplementation consumers need fall into these categories: Antioxidant(s), ...
By Algatech
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Evaluating Microbiome Therapies with Intestinal Cell Models
The microbiome has been shown to play roles in many different disease processes and is implicated in many more, from infectious and gastrointestinal diseases to autoimmune and neurological disorders. Advanced models of the gut leveraging intestinal and colonic stem cells are enabling the development of more reliable and robust systems for evaluating the impact of changes in the microbiome on gut ...
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