lung epithelial Articles
-
Nanomechanics of lung epithelial cells
Nanobiotechnology provides powerful tools for manipulating cells with nanometric resolution and with simultaneous measurement of force with pN resolution. We review the application of atomic force microscopy (AFM) and magnetic tweezers for probing cell nanomechanics. AFM measures the mechanical properties of the cell by indenting its surface by means of a flexible cantilever with a sharp tip at ...
-
Fabrication And Characterization Of 3D Bioprinted Triple-Layered Human Alveolar Lung Models
Researchers from Nanyang Technological University and its Center for 3D printing (SC3DP) have developed a 3D printed a highly repeatable and scalable three-dimensional in-vitro alveolar lung model using our REGENHU bioprinter, that could be exploited for pathogen translocation studies and respiratory-related toxicological testing applications. The triple-cell layered lung model was realized ...
By Regenhu
-
Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles
Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal lung disease. A maladaptive epithelium due to chronic injury is a prominent feature and contributor to pathogenic cellular communication in IPF. Recent data highlight the concept of a “reprogrammed” lung epithelium as critical in the development of lung fibrosis. Extracellular vesicles (EVs) are potent mediators of cellular ...
-
Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine
Abstract Electronic nicotine delivery systems (ENDS) or e-cigarettes have emerged as a popular recreational tool among adolescents and adults. Although the use of ENDS is often promoted as a safer alternative to conventional cigarettes, few comprehensive studies have assessed the long-term effects of vaporized nicotine and its associated solvents, propylene glycol (PG) and vegetable glycerin ...
-
Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2
The recent COVID-19 pandemic again highlighted the urgent need for broad-spectrum antivirals, both for therapeutic use in acute viral infection and for pandemic preparedness in general. The targeting of host cell factors hijacked by viruses during their replication cycle presents one possible strategy for development of broad-spectrum antivirals. By inhibiting the Raf/MEK/ERK signaling pathway, ...
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you