lung fibrosis Articles
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Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles
Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal lung disease. A maladaptive epithelium due to chronic injury is a prominent feature and contributor to pathogenic cellular communication in IPF. Recent data highlight the concept of a “reprogrammed” lung epithelium as critical in the development of lung fibrosis. Extracellular vesicles (EVs) are potent mediators of cellular ...
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Computer Vision-Based Digital Biomarkers Could Enable Faster and More Accurate In Vivo Assessment of Disease
At Recursion, we are working to decode biology and industrialize drug discovery. We have successfully executed over 82 million phenomic experiments and inferred over 179 billion biological relationships in our quest to identify promising novel therapeutic approaches. Now, we are extending our industrialized approach to petabytes of pre-clinical in vivo studies. Digitalizing in vivo studies ...
By Recursion
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When in Rome—SOT Funding Enables Training in Isolating and Culturing Mesenchymal Stem Cells
I was fortunate to receive the SOT Supplemental Training for Education Program (STEP) award. With this award, I traveled to Sapienza Università di Roma in Italy, to the laboratory of Dr. Rita Businaro for what was intended to be a three-month training period focused on mesenchymal stem cells (MSCs), cells that modulate immune response and tissue repair. Dr. Businaro is an expert in MSCs ...
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Benefits of point of care PFT in Rural Health
There’s an island in northern Lake Michigan called Beaver Island. It sits roughly 30 miles offshore of Michigan’s Lower Peninsula, part of an archipelago of other whimsically named islands (including Whiskey, Hog, Garden, and Hat). Roughly 500 hardy souls call Beaver Island home year-round, and the two townships that occupy the land support a small but stable economy that embodies the ...
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Discovery of Bispecific Antibodies and Immune Checkpoint Inhibitors That Kill Glioblastoma Cells and Melanoma Cells, and Block the Metastasis of Malignant Melanoma Cells to the Lung by Over 90%
Ocean Biomedical will be a wholly owned subsidiary of Aesther Healthcare Acquisition Corp. and will change its name to Ocean Biomedical, Inc., expected to be listed on NASDAQ under the symbol, “OCEA”. PROVIDENCE, R.I. and NEW YORK, Sept. 06, 2022 (GLOBE NEWSWIRE) -- Ocean Biomedical and Aesther Healthcare Acquisition Corp. (“Aesther”) (NASDAQ: AEHA) ...
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