Lung Injury Articles & Analysis
7 articles found
Dysregulation and Tissue Damage: The Inflammatory Trade-off While ELANE is crucial for defense, its unregulated activity is a major contributor to inflammatory tissue injury. The enzyme can degrade structural proteins in the lung, vasculature, and connective tissue. Key pathologies associated with excessive ELANE activity include: l Chronic obstructive ...
Extracellular adenosine provides protective effects by mitigating inflammation in conditions such as myocardial injury[7], acute lung injury[8], intestinal ischemia-reperfusion injury[9], and inflammatory bowel disease[10]. ...
I presented part of my doctoral research on how macrophages play a regulatory role in lung injury and fibrosis. During the meeting, I had several conversations with Dr. ...
After a lightning round of proposals and reviews, an international team of scientists led by Dr. Camillo Ricordi was granted immediate FDA authorization for a 24-patient clinical trial to test the safety and exploratory efficacy of umbilical cord-derived mesenchymal stem cells (UC-MSCs) to block the life-threatening lung inflammation that accompanies severe cases of COVID-19. The therapy uses ...
The research team pointed out that the lung injury of the dead was obvious, the lung was patchy, gray white focus and dark red bleeding were seen, and a large number of thick secretion overflowed from the alveoli in the section, suggesting that the new coronavirus mainly caused the inflammatory reaction characterized by deep airway and alveoli ...
Results: During NIV via a helmet with the simulator programmed in mild lung injury, exhaled air leaked through the neck-helmet interface with a radial distance of 150 to 230 mm when inspiratory positive airway pressure was increased from 12 to 20 cm H2O, respectively, while keeping the expiratory pressure at 10 cm H2O. ...
Methods: The HPS was positioned at 45 degrees on the bed and programmed to mimic mild lung injury (oxygen consumption, 300 mL/min; lung compliance, 35 mL/cm H(2)O). ...