medical research institution Articles
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High prevalence of psychological distress among healthcare workers during pandemic
Doctors more likely to experience depression while anxiety more common among Nurses A study by a team of researchers from the University of Wollongong (UOW), St George Hospital and the Illawarra Health and Medical Research Institute (IHMRI) has found a high prevalence of anxiety and depression among healthcare workers around the world during the COVID-19 pandemic. The researchers found that ...
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Genetic tools for select-agent-compliant manipulation of burkholderia pseudomallei
Department of Microbiology, Immunology and Pathology, Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, Colorado State University, Fort Collins, Colorado 80523-1682, and School of Medical Science and Institute for Glycomics, Griffith University—Gold Coast Campus, Gold Coast, Queensland 9726, ...
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Unveiling the Potential of Premade RNA-LNP Products
Introduction RNA Lipid Nanoparticles (LNP) technology has rapidly gained prominence in the health and scientific domain, primarily due to its significant role in carrying the mRNA of the COVID-19 vaccines developed by Pfizer/BioNTech and Moderna. Yet, the potential of this technology spans beyond the confines of these vaccines or even the health industry. As research into premade RNA-LNP products ...
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Innovative use of a bacterial enzyme involved in sialic acid degradation to initiate sialic acid biosynthesis in glycoengineered insect cells
Abstract The baculovirus/insect cell system is widely used for recombinant protein production, but it is suboptimal for recombinant glycoprotein production because it does not provide sialylation, which is an essential feature of many glycoprotein biologics. This problem has been addressed by metabolic engineering, which has extended endogenous insect cell N-glycosylation pathways and enabled ...
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Adventitious viruses in insect cell lines used for recombinant protein expression
Abstract Insect cells are widely used for recombinant protein expression, typically as hosts for recombinant baculovirus vectors, but also for plasmid-mediated transient transfection or stable genetic transformation. Insect cells are used to express proteins for research, as well as to manufacture biologicals for human and veterinary medicine. Recently, several insect cell lines used for ...
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The Structure of Key Proteins in Parkinson`s Disease Solved
Australian researchers have recently solved a multi-year mystery about Parkinson's disease. They solved the structure of a key protein that is expected to rapidly treat this incurable disease. The findings appear in Nature. For the first time, the researchers took a "live" shot of a protein called PINK1. The findings explain how this protein is activated in cells, thereby initiating the ...
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Too much sugar consumed at a young age can harm the brain and lead to mental disorders
Sugar is a direct source of sweetness that not only enhances the flavor of food but also serves as a source of energy for the body. Sugar is used in everyday life to give us a "sweet" feeling, whether it's in candy, cake, or cola. Sugar consumption is quickly increasing as material living standards rise, which not only leads to an increase in obesity rates, but also increases various health ...
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Breaking Barriers – Past and Current: Celebrating the Legacy of Dr. Clarice Reid, Pioneer in Sickle Cell Research, Biomark Diagnostics
Dr. Clarice Reid was a trailblazer in the field of sickle cell disease, dedicating her life and career to improving the lives of those affected by this debilitating genetic blood disorder. As a pioneering black woman in the field of medicine and science, Dr. Reid’s work has made a significant impact on our understanding of this condition and has paved the way for the development of ...
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