medicine biotechnology Articles
-
Impact of the life sciences on organisation and management of R&D in large pharmaceutical firms
The life sciences are having a significant impact on the organisation and management of R&D in large pharmaceutical firms, as well as restructuring the markets for new therapeutic products. However, there is continuing scepticism about large firms' ability or inclination to build in-house capacity for biologics and extract value from the life sciences. This paper explores the effect of life ...
-
Bioactive compounds obtained by immobilisation of serine protease inhibitors
We studied the preparation of polymeric membranes formed of solutions of poly–3–hydroxybutyrate (PHB) and chitosan. PHB–chitosan biomaterials from these solutions may form various structural types, which determine the biodegradation time, the adsorption capacity, and the kinetics of the release of medicinal compounds from polymeric matrices. Serine protease inhibitors, SERPINs, continue to catch ...
-
Protein Engineering: Designing Molecular Machines for a Healthier Future
Proteins are the workhorses of life, performing a vast array of essential functions, from catalyzing biochemical reactions to building and maintaining cellular structures. Protein engineering, a rapidly evolving field at the intersection of biology, chemistry, and computer science, aims to harness the power of these molecular machines by designing and manipulating their structure and function to ...
-
Understanding the Structure of the HIV Protein May Lead to New Treatments
Scientists from Rutgers University and Salk Institute have determined the molecular structure of HIV Pol polyprotein, which plays a key role in helping the virus spread itself and systemically. This finding may stimulate new treatments for more than 40 million AIDS patients worldwide. Their findings, published in Science Advances, could guide the development of drugs that bind to the protein ...
-
Unlocking the Possibilities of Customized Ionic Channel Expression Systems
Ionic channels, which are proteins present in the membranes of all living cells, are gaining significant importance in the fields of bio-medicine and biotechnology. They are responsible for the transmission of signals across cell membranes and are instrumental in multiple biological processes. This raises the demand for a systematic mechanism that can control their expression. The customized ...
-
The Reality and Future of Peptide Drugs
It has been said that the 21st century is the century of peptide drugs, and the fate of this substance, which lies between a large protein and a small molecule compound, is bound to be extraordinary. What are peptide drugs? Peptides are a class of compounds made up of amino acids linked by peptide bonds and are chemically active substances commonly found in living organisms. According to the ...
-
Microbial Fermentation -- a Cost Effective Way to Obtain Peptides
Peptides are short chains of amino acids that have various biological activities and therapeutic potential. They play crucial roles in various biological processes, such as cell signaling, enzyme activity regulation, and immune response modulation. Peptide fermentation allows for the production of peptides in sufficient quantities to meet the demands of research, clinical trials, and ...
-
RVx201 Herpes Vaccine
RVx201 Herpes Vaccine Description 2022 RVx201 is a first-in-human herpes simplex virus type 2 (HSV-2) live-attenuated therapeutic vaccine modified to be interferon sensitive that destroys the ability of the virus to inhibit immune responses. Produced by Rational Vaccines, Inc., the technology is based on the pioneering research of the late Dr. William Halford, who dedicated over 25 years to ...
-
Comprehensive protein interaction network helps discover candidate drugs for the treatment of COVID-19
Treatment options for COVID-19 remain limited. Researchers at the University of Helsinki and the University of Eastern Finland first searched for appropriate drug targets and reusable drugs and finally discovered six candidates with antiviral effects against SARS-CoV-2. Understanding viral pathogenesis at the molecular level is key to the development of effective therapies for COVID-19. The ...
By Profacgen
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you