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Metabolic Control Articles & Analysis

4 articles found

Unraveling the Secrets of the Acetyl-Code   

Unraveling the Secrets of the Acetyl-Code  

Thousands of non-histone proteins are also targets of lysine acetylation. This includes: Metabolic Enzymes: Acetylation can directly regulate the activity of key enzymes involved in glycolysis, gluconeogenesis, and fatty acid metabolism, linking cellular energy status (via acetyl-CoA levels) directly to metabolic control. ...

ByCreative Proteomics


Sugar Nucleotides: Building the Blocks of Life

Sugar Nucleotides: Building the Blocks of Life

Dysregulation of sugar nucleotide metabolism has been implicated in a number of diseases, including cancer, diabetes, and congenital disorders of glycosylation. ...

ByCD BioGlyco.


Contribution of galactofuranose to the virulence of the opportunistic pathogen aspergillus fumigatus

Contribution of galactofuranose to the virulence of the opportunistic pathogen aspergillus fumigatus

By a targeted gene deletion approach, we demonstrate that UDP-galactopyranose mutase, a key enzyme of galactofuranose metabolism, controls the biosynthesis of galactomannan and galactofuranose containing glycoconjugates. ...

ByAmerican Society for Microbiology (ASM)


Dynamics of glutamate synthesis and excretion fluxes in batch and continuous cultures of temperature-triggered Corynebacterium glutamicum

Dynamics of glutamate synthesis and excretion fluxes in batch and continuous cultures of temperature-triggered Corynebacterium glutamicum

In order to gain a better quantitative understanding of the factors controlling the metabolic transition, the fermentation dynamics was investigated for a temperature-sensitive strain cultivated in batch and glucose-limited continuous cultures. For non-excreting cells at 33°C, increasing the growth rate resulted in strong increases in the central ...

BySpringer-Verlag GmbH

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