Metabolic Regulation Articles & Analysis: Older
17 articles found
Secretome, the scientific field that studies the composition, structure, function, and regulation of secreted proteins in organisms. Secretome field aims to have a comprehensive understanding of the properties and functions of these proteins in order to study relevant issues in the fields of biology and medicine:Identifying Secreted ProteinsTechniques such as mass spectrometry ...
In these conditions, the altered availability of specific sugar nucleotides can lead to the synthesis of aberrant glycans with impaired function. Regulation of Sugar Nucleotide Metabolism The metabolism of sugar nucleotides is tightly regulated in cells to control the types and amounts of glycans that are synthesized. ...
Thyroid hormones play a vital role in regulating various metabolic processes throughout the body, including energy production, body temperature, heart rate, and growth. ...
Through lipid-lipid interactions and interactions between lipids and other biomolecules, a complex network of lipid metabolism is formed, which is involved in a large number of life activities. ...
This process occurs in plants through photosynthesis and in animals through various metabolic pathways. The synthesis of carbohydrates involves a series of enzymatic reactions that convert simple molecules into more complex structures. ...
Increasing the size of LNP and modifying the surface with hydrophobic molecules enhances the cellular uptake by Kupffer cells and promotes immune regulation. LSECs are located in liver sinusoids and are responsible for blood filtration, metabolic regulation, antigen presentation, and lipid metabolism. ...
Pancreatic cancer is a highly malignant digestive system tumor, and the five-year survival rate of patients after diagnosis is only about 10%. Changes in metabolism are one of the important features of tumor cells. Tumor cells undergo metabolic reprogramming to generate the substances, energy, and redox forces required for their rapid proliferation. ...
Nova2, which is involved in RNA splicing or metabolism regulation in a specific subset of developing neurons26, was highly enriched in the brain and neural tube. ...
In previous studies, it has been reported that deubiquitinase OTU family proteins play a key role in tumor cell apoptosis and drug resistance, but its role in energy metabolism remains unclear. Recently, Tsinghua University-Peking University Joint Center for Life Sciences, Peking University Professor Yin Yuxin's team, and Shandong First Medical University Affiliated Provincial ...
Purpose Dysregulations of key signaling pathways in metabolic syndrome are multifactorial, eventually leading to cardiovascular events. ...
Some lipids can both oxidize for energy supply and store energy when there is excess energy and thus, promoting metabolism. For example, triglycerides. (3) Regulates cellular function through oxidative metabolism, energy regulation, and mitochondrial electron transport chain. (4) Acts as a signaling molecule. For example, ...
MapMan analyses indicated that while nano‐titania up‐regulated overall metabolism metabolism in both tissues, metabolic processes under nano‐ceria remained mostly unchanged. ...
Rhodospirillum rubrum has the potential for biomass resource recycling combined with sewage purification. However, low biomass production and yield restricts the potential for sewage purification. This research investigated the improvement of biomass production, yield and organics reduction by Mg2+ in R. rubrum wastewater treatment. Results showed that with optimal dosage (120 mg/L), ...
Using DNA microarray and quantitative reverse transcription-PCR (RT-PCR) analyses, we found that sigB disruption led to reduced transcript levels of genes involved in the metabolism of glucose into organic acids. This in turn resulted in retardation of glucose consumption by cells under conditions of oxygen deprivation. These results indicate that SigB is involved in positive ...
Although efforts have been made to identify circadian-controlled genes regulating cell cycle progression and cell death, little is known about the metabolic signals modulating circadian regulation of gene expression. ...
We present here a novel Aspergillus nuclear protein, LaeA, as a global regulator of secondary metabolism in this genus. Deletion of laeA (laeA) blocks the expression of metabolic gene clusters, including the sterigmatocystin (carcinogen), penicillin (antibiotic), and lovastatin (antihypercholesterolemic agent) gene clusters. Conversely, ...
We present here a novel Aspergillus nuclear protein, LaeA, as a global regulator of secondary metabolism in this genus. Deletion of laeA (laeA) blocks the expression of metabolic gene clusters, including the sterigmatocystin (carcinogen), penicillin (antibiotic), and lovastatin (antihypercholesterolemic agent) gene clusters. Conversely, ...