metabolic system Articles
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Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease in mice
The gut microbiota, which includes Akkermansia muciniphila, is known to modulate energy metabolism, glucose tolerance, immune system maturation and function in humans1,2,3,4. Although A. muciniphila is correlated with metabolic diseases and its beneficial causal effects were reported on host metabolism5,6,7,8, the molecular mechanisms involved have not been identified. Here, we report thatA. ...
By KoBioLabs
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Dissolved Hydrogen Application
Hydrogen molecule is the smallest molecule in nature. It is extremely penetrating and extremely volatile. It can freely enter and exit the body cells, remove aging and toxic free radicals. After drinking, it enters human body tissues and diffuses to act on all organ line particles and nucleus. Absorbed by the body. Realize the balance of the environment in the body and initiate the mechanism of ...
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Applications of Microbial Whole Genome Sequencing
Microorganisms widely exist in nature and are closely related to human life and production. They are generally divided into fungi, actinomycetes, bacteria, spirulina, rickettsia, chlamydia, mycoplasma and viruses. Microbial whole genome sequencing is an important tool for mapping genomes of novel organisms, finishing genomes of known organisms, or comparing genomes across multiple samples. ...
By CD Genomics
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Effect of combined Low-Dose Radon- and Hyperthermia Treatment (LDRnHT) of patients with ankylosing spondylitis on serum levels of cytokines and bone metabolism markers: a pilot study
Ankylosing Spondylitis (AS) is a rheumatic disease and almost 50% of the affected patients suffer from osteoporosis. The ratio of Receptor Activator of Nuclear Factor κB Ligand (RANKL) and Osteoprotegerin (OPG) has become an important marker to assess the status of systemic bone metabolism and has been shown to be dysregulated in AS patients. Combined Low-Dose Radon- and Hyperthermia Therapy ...
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A New System for the Regulation of Glucose and Lipid Metabolism Found
Diabetes affects more than 400 million people worldwide and is a huge public health burden. Obesity is a major risk factor for diabetes and leads to insulin resistance that often precedes diabetes. Currently, genome-wide association studies (GWAS) have identified more than 80 diabetes susceptibility loci, and an increasing number of mutations and variants have been identified in monogenic forms ...
By CD BioGlyco.
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Exercise in the morning or in the evening has a completely distinct effect!
Life is all about working out. Moderate exercise not only strengthens the body, but also improves the metabolic state and slows the progression of diseases. However, different times of exercise may have different impacts, and it is an intriguing scientific question how to determine the best time to exercise. Although the influence of exercise on energy metabolism is well recognized, there is ...
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Pooled Human Cryopreserved Hepatocytes
Hepatocytes are the chief functional cells of the liver, responsible for the selective uptake, metabolism and excretion of most drugs. Cells for use in plate cultures or suspension assays represent a key tool for predicting properties such as hepatotoxicity, metabolism, and potential drug-drug interactions. Since these cells mimic the properties of the liver, researchers can evaluate the ...
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Organic Acids Analysis
The organism undergoes thousands of biochemical reactions every moment to maintain our growth, development and energy metabolism. Under normal circumstances, these biochemical reactions proceed smoothly step by step through various cycles or certain steps. The process by which the body changes carbohydrates, amino acids, and fats from nutrients to absorbable substances and wastes is called the ...
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What are Cannabinoids?
The term “cannabinoids” originally described bioactive constituents of the plant Cannabis sativa, a plant that can grow wild in mild, tropical climates around the world. For centuries, the cannabis ingredients were used traditionally for their medicinal purpose but also for their recreational properties; however, only since the 1940s have cannabinoids been purified from cannabis ...
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Academic research conclusion: Is exercising inside hyperbaric chamber the next big thing?
The beneficial effects of hyperoxia supplementation on oxygen transport system capacity, lactic acid metabolism capacity, power output performance, and endurance exercise tolerance have been described in multiple previous studies (Sperlich et al., 2017; Cardinale and Ekblom, 2018). With regard to exercise performance, Knight et al. (1993) used a combination of femoral arterial and venous ...
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The Reality and Future of Peptide Drugs
It has been said that the 21st century is the century of peptide drugs, and the fate of this substance, which lies between a large protein and a small molecule compound, is bound to be extraordinary. What are peptide drugs? Peptides are a class of compounds made up of amino acids linked by peptide bonds and are chemically active substances commonly found in living organisms. According to the ...
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Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine
Abstract Electronic nicotine delivery systems (ENDS) or e-cigarettes have emerged as a popular recreational tool among adolescents and adults. Although the use of ENDS is often promoted as a safer alternative to conventional cigarettes, few comprehensive studies have assessed the long-term effects of vaporized nicotine and its associated solvents, propylene glycol (PG) and vegetable glycerin ...
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What causes heart failure with preserved ejection fraction (HFpEF)?
Heart failure with preserved ejection fraction (HFpEF) is a multifactorial and multisystemic disorder that represents more than 50% of all heart failure cases.[1] Epidemiologic data from the Framingham Study, an international cohort study, shows a rapid increase in the prevalence of HFpEF over the past three decades, from 41% to 56% and, conversely, a decrease in the prevalence of HFrEF from 44% ...
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