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Metabolism Data Articles & Analysis

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Development of a list of reference chemicals for evaluating alternative methods to in vivo fish bioaccumulation tests

Development of a list of reference chemicals for evaluating alternative methods to in vivo fish bioaccumulation tests

The approach was based on: 1) inclusion of relevant chemical classes supported by high‐quality in vivo data for bioconcentration factor (BCF), whole body biotransformation rates (Kmet) and metabolism characterisation for rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio) (Tier I‐II); and 2) refinement to ensure a broad coverage of ...

ByJohn Wiley & Sons, Ltd.

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