Mitochondrial Function Articles & Analysis: Older
6 articles found
Mitochondria play a key role in maintaining cellular health and viability, and their dysfunction not only contributes to the development of many human diseases such as neurodegenerative diseases, cardiovascular diseases, obesity and type II diabetes, but also reduces oocyte quality and early embryonic development in animals. Mitochondrial function is dependent on ...
Ceramide is synthesized and secreted by lamellar vesicles, which together with cholesterol (25%) and free fatty acids (15%) constitute the intercellular lipids (ceramide 50%) involved in maintaining the skin barrier function. It also has various physiological and pharmacological functions, such as regulation of cellular immunity, delaying aging, and antitumor. ...
Sophisticated bioinformatics tools are able to reveal mitochondrial function and its contribution to cellular health and disease. Abnormal expression of mitochondrial proteins is the main cause of their dysfunction. Mitochondrial proteomics analyzes the dynamic changes of protein composition, expression level and modification ...
More than just components of cell membranes and energy storage substances, lipids can perform a variety of important biological functions in life activities. The structural diversity of lipids endows them with a variety of important biological functions: (1) they constitute an important component of the cell membrane. ...
Bisphenol A acts as an endocrine disruptor, affects animal reproductive success in vivo, and affects sperm functions in vitro at environmentally relevant concentrations leading to reduction in sperm motility and fertilizing ability in fish. The effect of in vitro BPA on avian sperm functions has not been explored. We tested the effect of environmentally relevant concentrations of BPA (0, 0.18, ...
We describe phylogenetic and functional studies of three septins in the free-living ciliate Tetrahymena thermophila. ...