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Molecular Diagnostics Articles & Analysis: Older

13 articles found

Ribonuclease: A Cornerstone of RNA Biology

Ribonuclease: A Cornerstone of RNA Biology

Enhancing the stability, specificity, and activity of these enzymes under various conditions could expand their application in synthetic biology, molecular diagnostics, and gene editing technologies. Structural biology techniques, such as X-ray crystallography and cryo-electron microscopy, are providing unprecedented insights into RNase function and guiding the ...

ByCreative Enzymes


Nanobodies Definition, Structure, Advantages and Applications

Nanobodies Definition, Structure, Advantages and Applications

Generally, the immunogenicity of the antibody is related to the molecular size, that is, the smaller the molecular weight, the smaller the immunogenicity of the antibody. The nanobody has a small molecular weight, only one domain, and lacks the Fc segment, which avoids the complement reaction caused by the Fc segment, and thus has a low ...

ByBOC Sciences


Whole Genome Sequencing for Rare Diseases

Whole Genome Sequencing for Rare Diseases

With over 7,000 rare diseases identified worldwide, their rarity makes them particularly challenging to diagnose accurately. Traditional diagnostic methods often involve time-consuming and costly procedures, such as multiple invasive tests, leading to delayed or missed diagnoses. Advances in genetic sequencing in molecular diagnostic techniques ...

ByProtheragen


qPCR for SARS-CoV-2 Detection and Research: Introduction, Principles, and Applications

qPCR for SARS-CoV-2 Detection and Research: Introduction, Principles, and Applications

Even so, numerous cases were noted in which the findings of the CT-scan were positive but the findings of the RT-PCR were negative at the initial presentation. Molecular diagnostics' effectiveness could rely on primers, probes, and reagents. For the molecular diagnosis of SARS-CoV-2, prior works have been published to evaluate certain ...

ByCD Genomics


The Tumor Marker: Vascular Endothelial Growth Factor 165 (VEGF165)

The Tumor Marker: Vascular Endothelial Growth Factor 165 (VEGF165)

On the other hand, other tumor markers are predominantly produced in stage III and IV tumors, and they have little significance in early screening. Tumor molecular diagnostic reagents are primarily used for detecting gene mutation sites, which can be measured when there is a variation in tumor cells. ...

ByBeta Lifescience


Ending tuberculosis by 2030: Are we close?

Ending tuberculosis by 2030: Are we close?

According to the WHO recommendations, the disease should be diagnosed using rapid molecular diagnostic tests. Some other diagnostic tools would include sputum smear microscopy and chest X-rays. ...

ByB Medical Systems


Reliable Ultra-Low Freezers for the Storage of Cancer Biomarkers

Reliable Ultra-Low Freezers for the Storage of Cancer Biomarkers

The use of tumour markers to diagnose, assess prognosis, and select a suitable cancer treatment has become possible due to the development of inexpensive and user-friendly molecular analysis tools such as the polymerase chain reaction (PCR). Maintaining the integrity of biomarkers during their processing and storage is therefore of critical importance to accurately diagnose and give prognosis ...

ByB Medical Systems


Rani is Opening Doors in Biosimilars, Challenging Humira and Others

Rani is Opening Doors in Biosimilars, Challenging Humira and Others

Most Read Today Two Remarkable Women of Takeda's C-Suite Make the Professional Personal Medical Image Processing Software Market Insights [Size | Share | Trends | Industry Analysis] – Forecast [2020-2030] Mesenchymal Stem Cells Market Prospects and Growth Assessment Molecular Diagnostics Market Outlook, Competitive Landscape and Forecasts to 2028 ...

ByRani Therapeutics


Betting big on quantitative neurobiomarkers

Betting big on quantitative neurobiomarkers

In the precision medicine era, diagnostics have become integral to the development of novel therapeutics. Oncology has led the way with molecular diagnostics supporting an explosion of investment and innovation in targeted therapeutics. ...

ByBeacon Biosignals, Inc.


Mic and Myra Prove Flexible and Reliable in Regional Mobile Labs

Mic and Myra Prove Flexible and Reliable in Regional Mobile Labs

In this paper, Paton et al set out to test an optimal open platform for mobile molecular diagnostics in Derby and Broome in north-western Australia, given that both towns are located more than 1,600km from centralised testing services. The choice was made to field test a Mic magnetic induction thermal cycler and Myra liquid handling robot from Bio ...

ByBio Molecular Systems


Ensuring ultra-pure air in a Mobidiag molecular diagnostics laboratory - Case Study

Ensuring ultra-pure air in a Mobidiag molecular diagnostics laboratory - Case Study

Developing and manufacturing molecular diagnostics platforms and test kits for detecting human pathogens. Specializing in Antimicrobial Resistance Management and Hospital Associated Infections (HAIs), by reliable, cost-effective molecular diagnostic solutions for detecting Gastrointestinal Infections including most ...

ByGenano Industrial Air Purification Solutions - Genano Ltd.


Effective DNA extraction method for molecular diagnostics on wood-decay fungi

Effective DNA extraction method for molecular diagnostics on wood-decay fungi

INTRODUCTION Strategically eliminating damage caused by fungus requires precise identification of the fungal species present (using either conventional or molecular diagnostic techniques). The first step in performing molecular diagnostics on wood-decay fungi is to obtain analyzable fungal DNA. ...

ByAnalytik Jena - an EndressHauser Company


Mass spectrometry meets medical sciences: making headway in molecular disease diagnostics

Mass spectrometry meets medical sciences: making headway in molecular disease diagnostics

No ...

BySpringer-Verlag GmbH

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