Molecular Pathway Articles & Analysis: Older
14 articles found
Their ability to modulate various biological processes makes them significant players in the field of molecular biology and medicine. Among the various tools utilized in research and therapeutic applications, miRNA mimics have emerged as powerful instruments for manipulating and studying gene expression. ...
Zebrafish and mammals share common molecular pathways for tumor progression. Likewise, more than 130 different genes in zebrafish liver tumors exhibited expression similar to those characteristic of human liver cancers, correlating with histological tumor type, grade, and stage. ...
Anorexia, a condition characterized by a significant reduction in food intake despite negative energy balance, poses severe risks to health and quality of life. It manifests in various forms in humans, including anorexia nervosa and physiological anorexia. While psychological and social factors have been widely studied, the physiological causes remain less understood. For ground squirrels, ...
Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events. Journal of the American College of Cardiology, 58(20), 2047-2067.2. ...
ByMatexcel
Proteomics: A large-scale study of the proteome, the entire set of proteins expressed by the genome, can identify protein signaling pathways that are disrupted in brain tumors. Proteomic analysis can reveal potential biomarkers for diagnosis and targets for new treatments1. ...
Small molecule drugs are crucial for targeting the molecular pathways and signaling mechanisms involved in the growth and development of brain tumors. ...
Understanding Complex Diseases: Many diseases, such as cancer and neurodegenerative disorders, are multifaceted and involve intricate molecular pathways. Drug-disease relationship analysis helps in unraveling these complexities by revealing the key players in disease progression. ...
By subjecting DEGs to gene ontology enrichment analysis, pathway analysis, or functional annotation, we gain insights into the biological processes, molecular functions, and pathways associated with the observed gene expression changes. ...
By exposing these cells to various drug candidates, scientists can evaluate their effects on cellular viability, proliferation, and specific molecular pathways. Such screening processes help identify promising drug candidates and eliminate those with undesirable effects, saving time and resources in the drug development pipeline. ...
By subjecting DEGs to gene ontology enrichment analysis, pathway analysis, or functional annotation, we gain insights into the biological processes, molecular functions, and pathways associated with the observed changes in gene expression. ...
Scientists use M-HTS to quickly test thousands of samples with biological activities at the model organism, cell, pathway, or molecular levels. Large compound libraries therefore can be screened in a cost-effective way which helps to accelerate target analysis. l Virtual ScreeningVirtual screening is a computer-based technology used to analyze the presence or ...
The bioprinted constructs allowed the in vitro study of chondrogenic signaling pathways, as well as the role of TGF-β signaling. This was achieved by means of a thorough proteomic analysis and evaluation of the protein expression related to cartilage-specific signaling pathways. ...
ByRegenhu
Due to the diverse yet interconnected nature of this field, it integrates psychology, physics, chemistry and cutting-edge molecular biology in an effort to understand the complex nervous system and its role in cognition. ...
As few studies have addressed the toxicity of these specific phthalates in most organisms, this study used higher concentrations of these chemicals to determine their toxicity pathways in amphibians and at the same time investigate a suite of genes known to be altered by the well‐studied phthalates. Both DMP and DCHP increased larval mortality (9.1 to 924.0 mg/L DMP and 4.1 to ...