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Mtor Protein Articles & Analysis

2 articles found

Highlight the Everolimus metabolic effects on breast cancer

Highlight the Everolimus metabolic effects on breast cancer

In this study, researchers examine the effects of two drugs, everolimus and metformin, on triple-negative breast cancer. Everolimus blocks a protein called mTOR, while metformin blocks part of the mitochondria, the energy powerhouses of cells. ...

ByBertin Technologies


The TSC1-TSC2 complex is required for proper activation of mTOR complex 2

The TSC1-TSC2 complex is required for proper activation of mTOR complex 2

The mammalian target of rapamycin (mTOR) is a protein kinase that forms two functionally distinct complexes important for nutrient and growth factor signaling. Both complexes phosphorylate a hydrophobic motif on downstream protein kinases, which contributes to the activation of these kinases. mTOR complex 1 (mTORC1) ...

ByAmerican Society for Microbiology (ASM)

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