muscle tissue Articles
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Inorganic elements in green sea turtles (Chelonia mydas): Relationships among external and internal tissues
Inorganic elements from anthropogenic sources have entered marine environments worldwide and are detectable in marine organisms, including sea turtles. Threatened and endangered classifications of sea turtles have heretofore made assessments of contaminant concentrations difficult due to regulatory restrictions on obtaining samples using non‐lethal techniques. In the present study, claw and ...
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Mercury concentrations in different tissues of turtle and caiman species from the Rio Purus, Amazonas, Brazil
Total mercury (Hg) concentrations of muscle, liver, blood, and epidermal keratin were measured in typically consumed, economically and culturally important species of turtle (Podocnemis unifilis and Podocnemis expansa) and caiman (Melanosuchus niger and Caiman crocodilus) from the Rio Purus in the Amazon basin, Brazil. Methylmercury (MeHg) concentrations were also measured in muscle tissue, ...
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Mercury and selenium concentrations in skeletal muscle, liver and regions of the heart and kidney in bearded seals from Alaska
Mean concentrations of total mercury [THg] and selenium [TSe] (mass and molar based) were determined for five regions of the heart and two regions of the kidney of bearded seals (Erignathus barbatus) harvested in Alaska in 2010–2011. Mean [THg] and [TSe] of bearded seal liver and skeletal muscle tissues were used for intertissular comparison. Se:Hg molar ratios were used to investigate ...
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Influence of carbon and lipid sources on variation of mercury and other trace elements in polar bears (Ursus maritimus)
In the present study, the authors investigated the influence of carbon and lipid sources on regional differences in liver trace element (As, Cd, Cu, total Hg, Mn, Pb, Rb, Se, and Zn) concentrations measured in polar bears (Ursus maritimus) (n = 121) from 10 Alaskan, Canadian Arctic, and East Greenland subpopulations. Carbon and lipid sources were assessed using δ13C in muscle tissue and fatty ...
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Cholinesterase activity of muscle tissue from freshwater fishes: Characterization and sensitivity analysis to the methyl‐paraoxon organophosphate
The biochemical characterization of cholinesterases (ChE) from different teleost species has been a critical step ensuring proper use of ChE activity levels as biomarkers on environmental monitoring programs. In the present study, ChE from Oreochromis niloticus, Piaractus mesopotamicus, Leporinus macrocephalus and Prochilodus lineatus were biochemically characterized by specific substrates and ...
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Distribution of Oxytetracycline residues in eggs from orally administered hens
Twenty five-week old hens (n = 6) were administered with an oral dose of 75 mg of Oxytetracycline (OTC) hydrochloride per day per head for five consecutive days and its residues in eggs as well as breast, leg and liver tissues were analysed by a high-performance liquid chromatography-ultraviolet visible detection (HPLC-UV) technique. The highest OTC residue concentration in egg white (0.5944 µg ...
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Evidence of impaired health in yellow perch (Perca flavescens) from a biological mercury hotspot in northeastern North America
Few studies have investigated the effects of Hg on wild fish from remote areas, even though these fish can have high total Hg concentrations. In Kejimkujik National Park and National Historic Site (KNPNHS), Nova Scotia, Canada, concentrations of total Hg in many yellow perch (Perca flavescens) currently exceed the estimated threshold level for adverse effects in fish (0.2 µg Hg g−1 (wet wt), ...
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Understanding Pediatric Cardiomyopathy: Causes, Symptoms and Treatment Options
Up to 5,000 American infants and children are diagnosed with pediatric cardiomyopathy each year. Learn more about this rare but potentially serious condition. Cardiomyopathy, which is a general term for diseases of the heart muscle, is relatively rare in children, affecting only about 12 out of every 1 million Americans under the age of 18. Among the approximately 1,000 to 5,000 new cases ...
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Scientists use lipid nanoparticles to precisely target gene-editing tools to the lung
Safe and effective systemic delivery of mRNA to specific organs and cells in vivo remains a major challenge in the development of mRNA-based therapies. Currently, the application of mRNA-based technologies is largely limited to liver diseases because of the lack of specific and effective extrahepatic systemic mRNA delivery systems in vivo. Now, a team of researchers has fine-tuned the existing ...
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SPACE BIO-3D PRINTING FROM HUMAN CARTILAGE TO THYROID GLAND IN RODENTS AND TO SPACE ARTIFICIAL MEAT
Space bio-3D printing from Human Cartilage to Thyroid Gland in Rodents and to Space Artificial Meat: SUNKYE Satisfies the Connection and Signal System of Bio-3D Printing in Micro-gravity Environment Space bio-3D printing may be a concept we've heard recently. But as with 3D printing technology, there was only a short accumulation before it happened! Do we need Space bio-3D printing? Can't we ...
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What Are Sphingolipids?
Structure and metabolism of sphingolipids Recently, more than 300 species of sphingolipids have been identified and characterized as long-chain sheath-like base backbones. Ceramide is the aminoacylation product of sphingosine at the 2-carbon position, which has strong biological activity and is a basic structural unit of sphingolipids. The simplest forms of sphingolipids include phosphoceramides ...
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Exercise in the morning or in the evening has a completely distinct effect!
Life is all about working out. Moderate exercise not only strengthens the body, but also improves the metabolic state and slows the progression of diseases. However, different times of exercise may have different impacts, and it is an intriguing scientific question how to determine the best time to exercise. Although the influence of exercise on energy metabolism is well recognized, there is ...
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Sublethal propoxur toxicity to juvenile common carp (Cyprinus carpio L., 1758): Biochemical, hematological, histopathological, and genotoxicity effects
The sublethal toxicological and genotoxic potential of propoxur, a widely used carbamate insecticide against household pests, in veterinary medicine, and in public health, was evaluated on carp as a model species (Cyprinus carpio L., 1758) using the erythrocyte micronucleus test. Based on the 96‐h lethal concentration, 50% (LC50) data from the U.S. Environmental Protection Agency ECOTOX Database ...
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Huateng Pharma Supplies Canagliflozin Intermediates With Commercial Scale Production
Canagliflozin is a medication used to treat type 2 diabetes. It is a third-line medication to be tried after metformin, a first-line medication for type 2 diabetes. It is used together with exercise and diet. It is not recommended in type 1 diabetes. Mechanism action of Canagliflozin Canagliflozin is a sodium-glucose cotransporter (SGLT2) inhibitor. Glucose filtered in the renal tubular lumen is ...
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Best Material To Practice Your Suturing Skills
You've probably heard amazing stories of surgeons performing successful, yet extremely delicate and risky procedures such as open-heart surgery, separation of conjoined twins, craniotomy, thoracic aortic dissection repair, oesophagectom, spinal osteomyelitis surgery, and many more. As a medical student, you wonder how a surgeon can do such an incredible job. Well, the answer lies in lots of ...
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A Difficult Needle to Thread
Do you know what it’s like to wake up in a different stranger’s house every morning? To open your eyes and immediately feel extremely uncomfortable, alarmed, unsafe, out of place, lost, dizzy, like your world is the most upside-down it’s ever been? Do you remember what it was like to be a kid tagging along to the grocery store with your parents? One second ...
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Cultured Protein: A Guide to Every Cell-Based Meat Startup in the World Right Now
The alternative protein market is on fire right now, estimated to be worth approximately $2.2Bn, and cultivated meat is expected to play an important role in the shift from traditional meat products. Experienced scientists are engaged in cellular agriculture with the aim of reducing animal-based agriculture’s negative impact on both the planet and the suffering of animals and at the same ...
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Increased insulin action in skip heterozygous knockout mice
Insulin controls glucose homeostasis and lipid metabolism, and insulin impairment plays a critical role in the pathogenesis of diabetes mellitus. Human skeletal muscle and kidney enriched inositol polyphosphate phosphatase (SKIP) is a member of the phosphatidylinositol 3,4,5-trisphosphate phosphatase family (T. Ijuin et al. J. Biol. Chem. 275:10870-10875, 2000; T. Ijuin and T. Takenawa, Mol. ...
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What Is Collagen?
Collagen is a family of proteins. At least 30 kinds of genes encoding collagen chains have been found, which can form more than 16 kinds of collagen molecules. According to its structure, it can be divided into fibrous collagen, basement membrane collagen, microfibrillar collagen, anchored collagen, hexagonal reticular collagen, non-fibrous collagen, transmembrane collagen, etc. According to ...
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Predicting cardiotoxicity with engineered 3D human cardiac tissue models
Cardiovascular safety liabilities caused 52.3 % of 44 marketed data from 1980 to 2011, and cardiovascular disease remains the leading cause of death globally, yet only 8.7% of cardiovascular drugs successfully pass clinical trials. These statistics demonstrate the need to address a patient’s specific genetic make-up and phenotype by adopting a personalized treatment methodology for ...
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