myocardial infarction Articles
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Incidence of blood circulation system illnesses among liquidators of Chernobyl accident living in Belarus
In this paper, the incidence of the illnesses of blood circulation system (IBCS) among liquidators of the Chernobyl accident living in Belarus is described. The increase of the incidence of the IBCS as a whole was found to be 19.5%, that of hypertensive diseases 52.0%, and that of acute and subsequent myocardial infarction 53.2%. The incidence of cerebral infarction increased by a factor 10. An ...
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Role of the left ventricular cavity-to-myocardium count ratio in resting technetium-99m-Sestamibi SPECT in the recovery of myocardial function after thrombolytic therapy in patients with acute myocardial infarction
The aim of this study was to assess the value of the Cavity-to-Myocardium count ratio (CM ratio) calculated in the resting 99mTc-Sestamibi SPECT images to identify myocardial functioning status and recovery of myocardial function in patients with acute myocardial insult who have received thrombolytic therapy. The study demonstrates that the resting 99mTc-Sestamibi SPECT CM ratio can be used to ...
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Development of fabrication technique in nano–scale resveratrol by collagen
Resveratrol (3,5,4′–trihydroxy–trans–stilbene, RSV), is found in various plants, including grapes, berries and peanuts. It is also present in wines, especially red wines. RSV has potent antioxidant, anti–inflammatory, and chemo–protective properties used as a biologically active supplement in the prophylaxis of myocardial infarction, diabetes, and tumours. The aim of this study was using ...
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A Contemporary Review of ST-Elevation Myocardial Infarction: Pathophysiology, treatment options and hot topics
Pathophysiology, treatment options and hot topics Improvements In Stemi Treatment The immediate and long-term prognosis of patients experiencing an ST segment elevation myocardial infarction (STEMI) has changed dramatically since the introduction of coronary reperfusion therapies during primary percutaneous coronary intervention (pPCI). The evolution of these therapies accelerated with the ...
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Will Metformin Be Replaced By SGLT-2 Inhibitors
Metformin is a classic first-line hypoglycemic agent for patients with type 2 diabetes, and is an essential drug in combination regimenes. However, as the evidence is updated, the idea of drug selection for first-line treatment is changing. GLP-1 agonists and SGLT-2 inhibitors in combination with or without metformin (as required for glycemic management) have also been recommended by multiple ...
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Noninvasive, Transthoracic, Low-Frequency Ultrasound Augments Thrombolysis in a Canine Model of Acute Myocardial Infarction
Background - Limitations of coronary thrombolysis include the time to reperfusion, patency rate, and bleeding. We evaluated the use of noninvasive transcutaneous ultrasound to augment coronary thrombolysis. Methods and Results - In 24 dogs, a thrombotic occlusion of the left anterior descending coronary artery was induced and documented by 12-lead ECG and coronary angiography. After $60 minutes ...
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Physiology and Pathology of Coronary Microcirculation
The heart is a unique organ in many respects since its activity is mandatory to sustain life. The heart’s circulatory system and coronary flow regulation are highly adapted to the vital role of the heart in sustaining life and to everyday physiological challenges. Understanding coronary physiology is key for treating patients with ischemic heart disease in general, and ...
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Unveiling The Manifold Potentials: Mesenchymal Stem Cells & Bone Marrow Mesenchymal Stem Cells
In the vibrant realm of cellular biology and regenerative medicine, mesenchymal stem cells (MSCs) hold unparalleled potential for therapeutic applications. Particularly noteworthy are bone marrow mesenchymal stem cells (BM-MSCs), a subtype of MSCs. Their unique properties make them indispensable resources for developing ground-breaking solutions for various medical conditions. Mesenchymal stem ...
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The Function and Application of the Magic Superoxide Dismutase
Some substances can easily interact with the oxygen in the air when exposed to the air, causing chemical changes in the substance. This is the process of oxidation. Sun exposure, air pollution, radiation, etc. will cause the human skin to produce a large amount of superoxide free radicals, and its strong oxidizing ability will accelerate the speed of skin oxidation, and may even cause serious ...
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What Are the Applications of Enzymes in Disease Research and Treatment?
With the development of biotechnology in the modern information age, the research, development and utilization of enzymes have become more and more in-depth, and correspondingly, the application of enzymes in medicine has become more and more extensive. 1. The relationship between enzymes and certain diseases The diseases caused by the lack of enzymes in the human body are mostly congenital or ...
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Efficacy and Detection of Ceramide
Ceramides are composed of sphingosine analogs and long-chain fatty acids bound by amide bonds, and are the most important of the sphingolipid compounds. Ceramide is synthesized and secreted by lamellar vesicles, which together with cholesterol (25%) and free fatty acids (15%) constitute the intercellular lipids (ceramide 50%) involved in maintaining the skin barrier function. It also has various ...
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The Functions and Roles of Enzymes
Catalysis Enzymes are a class of biological catalysts. They govern many catalytic processes such as metabolism, nutrition, and energy conversion of organisms. Most of the reactions closely related to life processes are enzyme-catalyzed reactions. These properties of the enzyme enable the intricate process of material metabolism in the cell to proceed in an orderly manner, and to adapt material ...
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A Paradigm Shift in the Treatment of Venous Thromboembolic Disease
PE is the most common preventable cause of death among hospital patients in the United States. VTE is a leading cause of death and disability worldwide and has the third-highest mortality rate out of any cardiovascular disease, behind myocardial infarctions and stroke. Unlike myocardial infractions and stroke, where mortality has improved considerably, VTE has seen an increase in cases, with no ...
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Cellular and molecular differences between HFpEF and HFrEF
Heart failure affects about 6.2 million Americans and is rising in prevalence. With half of these cases presenting as heart failure with preserved ejection fraction (HFpEF), it’s essential for both the medical community and the population at large to have a better understanding of its pathology. [1,2] Knowing the differences between HFpEF and its counterpart, heart failure with reduced ...
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Emerging therapy for HFpEF: SGLT2 inhibitors
Recent clinical trials investigating sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with heart failure with preserved ejection fraction (HFpEF). HFpEF is a complex disease which accounts for more than half of all heart failure (HF) hospital admissions and is an increasing disease burden. [1] The prevalence of HFpEF is ...
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How One Smart MedTech Company is Leveraging Innovation to Save the Lives and Limbs of VTE Patients
Medical device start-up companies must focus on innovation, regulatory compliance, efficient processes and prudent financial management in order to survive. Smart MedTech companies prioritize their funding to only support innovation which will result in new products that fulfill significant unmet clinical needs over the long-term. Thrombolex, a relatively new entrant into the MedTech sector, is a ...
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