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Neurology Disorder Articles & Analysis: Older
23 articles found
They are implicated in a wide range of conditions, from cardiovascular and metabolic disorders to neurological diseases and cancers. By facilitating the early stages of the drug development pipeline, GPCR Screening Services help streamline the identification of lead compounds, optimizing the chances of successful therapeutic outcomes. ...
The process of iPSC differentiation to neurons and neuronal cells is of special importance for neurobiology and related disorders, considering the dearth of clinically relevant in vitro models available for research, drug screening and development, as well as the lack of therapy to reverse neuronal damage. Benefits and advantages of iPSC differentiation to neural stem cells ...
The high selectivity, resistance-overcoming capabilities, and ability to target previously undruggable proteins make PROTACs effective in various diseases, including neurological disorders, inflammatory diseases, and cancer. Peptide-Based SM-PROTAC Traditional PROTACs are linear structures that connect target protein ligands and E3 ligands with suitable linkers. ...
(5) Neurobiology: In the field of neuroscience, CD Genomics' Ribo-seq services offer insights into translational regulation in the brain and nervous system, supporting research on neurological disorders and neurodevelopment. (6) Plant Biology: Ribo-seq services are pivotal in studying how plants adapt to various growth conditions and environmental ...
They also exhibit promising results in treating neurological disorders, diabetes, liver diseases, and in cancer therapy. ...
Chimeric RNAs have also been implicated in other diseases, such as neurological disorders. Sequencing Technologies for Chimeric RNA Detection Chimeric RNA molecules, which arise from genomic rearrangements, alternative splicing, or fusion events, have emerged as crucial players in diverse biological processes and disease pathogenesis. ...
From exploring their roles in some neurological disorders, cardiovascular diseases to electrolyte imbalance—it's a resourceful tool. ...
More than a dozen viral gene therapy products have been approved for the treatment of cancer, infectious diseases, and rare single-gene disorders. The main types of viral vectors used clinically for in vivo gene therapy include adenovirus, adeno-associated virus (AAV), herpes simplex virus (HSV), retroviruses, and lentiviruses. ...
In late November, EpiFinder Co-Founder Neel Mehta and Creative Officer Kristi Kietzmann left Arizona for a cross-country road trip. The journey from Arizona to Washington D.C. covered 5,504 miles over 22 days. At Washington D.C., CEO Robert Yao and other team members joined them for the 71s American Epilepsy Society (AES) conference. There, the team held 3 days of exhibits and presented. Why ...
Epigenetic factors such as DNA methylation, histone modifications, and non-coding RNAs are associated with a variety of diseases such as tumorigenesis, immunodeficiency diseases, neurological disorders, cardiovascular diseases, and psychiatric disorders. ...
Several improvements support the hypothesis that dynamic standing using the Innowalk is effective as an add-on to standard therapy in the treatment of children and young people with severe motor impairments. The study included 46 patients where 50% were diagnosed with cerebral palsy and 50% with diverse syndromes. The results show improvements on: Passive assisted motion (79%) Stimulation ...
The discovery could lead to better new treatments for neurological disorders such as anxiety, autism spectrum disorder, schizophrenia and Parkinson's disease. In determining the structure of this transporter, one of the smallest proteins ever made, researchers have opened up new avenues to improve drugs for a variety of debilitating diseases, ...
The relationship between lncRNAs and diseases is well established, especially in chronic disorders. However, cancer is one of the most intensively studied diseases associated with lncRNAs. ...
Introducing Beacon Biosignals: a neurotechnology company founded to develop machine learning-enabled EEG neurobiomarkers and accelerate precision medicine for any disease state affecting the brain Founded by MD/PhDs and engineers from Harvard and MIT, Beacon is propelled by the vision of a computing platform designed to scale the interrogation of large brain datasets with unprecedented ...
The effectiveness of kinases as targets for other diseases, including neurological disorders, inflammation and metabolic diseases, is also being tested. ...
Abstract—The current study aims to evaluate the performance of the Circadia Sleep Analysis Algorithm, which - in combination with the non-contact and minimally invasive Circadia bedside monitor - allows for long-term sleep assessment and continuous evaluation of sleep therapy outcomes. The Circadia Contactless Respiratory Monitor was initially used to record 17 nights of sleep data from 9 ...
The microbiome has been shown to play roles in many different disease processes and is implicated in many more, from infectious and gastrointestinal diseases to autoimmune and neurological disorders. Advanced models of the gut leveraging intestinal and colonic stem cells are enabling the development of more reliable and robust systems for evaluating the impact of ...
1 billion people around the world are currently suffering from neurological disorders, and the number is growing by the day. The COVID-19 pandemic has had a significant negative impact on the healthcare system’s ability to effectively diagnose and treat these individuals. ...
Abstract Reactive astrocytes are associated with every form of neurological injury. Despite their ubiquity, the molecular mechanisms controlling their production and diverse functions remain poorly defined. ...
Alcyone Lifesciences is a medical technology company based out of Lowell, MA, which specializes in central nervous system (CNS) drug delivery platforms for targeted infusions of the brain or spinal cord. Their Thecaflex DRx System was recently awarded Breakthrough Device designation by the FDA, for spinal infusion of therapeutic medications. Medgadget had the opportunity to speak with Alcyone ...