Oncology Research Articles & Analysis
144 articles found
The large T antigen of SV40 has the capability to bind and inactivate tumor suppressor proteins such as p53 and Rb, which are critical regulators of the cell cycle. Significance in Research The creation of SV40-immortalized human ovarian epithelial cells represents a breakthrough for oncology and reproductive biology. ...
In recent years, the field of gene editing has experienced groundbreaking advancements, with CRISPR/Cas9 emerging as a powerful technology for precise genetic manipulation. Among various delivery systems, lentiviruses have garnered significant attention due to their ability to introduce genetic material into both dividing and non-dividing cells, making them an ideal vehicle for gene therapy ...
Enzymes have always served as the silent drivers behind countless biological processes, but their role in applied science has never been more crucial. As modern biotechnology advances, the application of enzymes in industrial biotechnology, medical diagnostics, and sustainable manufacturing has evolved into a multidisciplinary field, leveraging protein engineering and synthetic biology to unlock ...
These subgroups interact in a complex signaling network to decide a cell’s fate. Clinical Importance and Research Highlights One of the most significant areas of BCL2-related cancer research involves the development of BCL2 inhibitors. ...
Through the synergy of recombinant DNA technology and high-throughput screening researchers develop therapies specifically designed to match the distinctive traits of tumors expressing FAP. ...
Cancer treatment has witnessed transformative advancements over the past few decades, notably with the emergence of CAR-T (Chimeric Antigen Receptor T-cell) therapy. This revolutionary therapy harnesses the body's immune system by genetically engineering T-cells to target and destroy cancer cells. Among the pioneering companies at the forefront of this innovation is Alfa Cytology, renowned for ...
Fluorescence In Situ Hybridization (FISH) and Immunohistochemistry (IHC) are two powerful techniques widely used in biological and medical research. While each has its strengths, the combination of these methods—ImmunoFISH—offers a unique and comprehensive approach to investigation at the cellular and tissue levels. Understanding the Techniques FISH is primarily utilized for detecting ...
The main focus of drug carrier research today is to identify carriers that are both safe and effective for clinical treatment applications. As treatment strategies advance researchers regularly update drug delivery systems. Traditional drug delivery systems consist of liposomes and polymer micelles together with nanoparticles but despite their inclusion in clinical trials current versions still ...
Histological image analysis has emerged as a pivotal domain in biomedical research and clinical diagnostics, allowing scientists and healthcare professionals to decipher the intricate structures of tissues at a microscopic level. ...
Alfa Cytology, which stands at the forefront of oncology service provision in New York United States, has announced its sophisticated antibody-drug conjugates(ADCs) development services for cancer. ...
In the realm of biomedical research, the study of cytokines and chemokines plays a pivotal role in understanding the immune system and its responses to various stimuli. For researchers working with rat models, the Rat Cytokine and Chemokine Panel offers an invaluable set of tools to investigate these complex signaling molecules. In this article, we will explore what cytokines and chemokines are, ...
The Tricarboxylic Acid (TCA) Cycle, also known as the Krebs Cycle or Citric Acid Cycle, is a fundamental metabolic pathway that plays a crucial role in cellular respiration. This cycle is integral to the process by which cells extract energy from carbohydrates, fats, and proteins, making it a cornerstone of bioenergetics in living organisms. What is the TCA Cycle? The TCA Cycle takes place in ...
In the rapidly evolving field of cellular biology and genetic engineering, the development of efficient and reliable cell lines is vital for research and therapeutic applications. One such advancement is the establishment of the Monkey DLL3 stable cell line using HEK293T cells. This article provides an overview of the significance of this cell line, its applications, and the methodology behind ...
In the ever-evolving landscape of cancer research, two intriguing concepts have emerged that are reshaping how scientists approach treatment: synthetic lethality and parthanatos. ...
Alfa Cytology unveils advanced PD-1 inhibitor development service for cancer research. Alfa Cytology, a prominent service provider in the oncology landscape, has recently launched its innovative PD-1 inhibitor development services. ...
The cell cycle is an essential biological process that enables cells to grow, duplicate their DNA, and divide into daughter cells. This cycle is carefully regulated by proteins to ensure accuracy in cell replication. Disruptions in these controls can lead to uncontrolled cell division, a hallmark of cancer and other diseases. Cell cycle progression is orchestrated by key proteins, including ...
National No Smoking Day is observed in the UK annually on the second Wednesday of March, falling on the 12th of March 2025. Inaugurated on Ash Wednesday in 1984, the day aims to raise awareness of the dangers of smoking and encourage smokers to quit, highlighting the benefits of a smoke-free life. Smoking poses serious health risks, affecting nearly every organ in the body. Smokers significantly ...
These avant-garde solutions are built upon a profound understanding of tumor immunology and cellular signaling pathways, empowering researchers to strengthen research on experimental therapies. “Our cancer immunotherapy development services embody our unwavering commitment to empowering oncology research and ...
Alfa Cytology, a prominent services provider in oncology, has launched its cutting-edge ovarian cancer therapy development services. ...
Understanding the immune system is fundamental to advancing biomedical research, especially in areas such as cancer, autoimmune diseases, and infectious diseases. Mouse models play a pivotal role in this field, as their immune system shares many similarities with that of humans. A key aspect of studying the immune system involves analyzing cytokines, chemokines, and growth ...