organ-on-a-chip Articles
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UCT Silane Cited in Organ-On-Chip
The ventricular myocardium of the human heart is composed of an anisotropic tissue structure that allows for force generation and contraction to pump blood throughout the body. It has long been established that the collagen-rich, fibrous, extracellular matrix environment guides the formation of this laminar tissue architecture. The structural and mechanical properties of the cardiac ...
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Increasing the Efficiency of Drug Development with Preclinical Testing Using Human Intestinal Stem Cells
Due to a lack of robust in vivo gut models, animal studies are generally required to evaluate gut toxicity. However, these studies can be lengthy and expensive and may not accurately recapitulate the behavior of the human gastrointestinal tract. Drugs are thus often developed with undesired gut side effects that are not apparent until clinical trials. Organ-on-a-chip models are the closest ...
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