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Osteoporosis Articles & Analysis: Older

21 articles found

Multi-Method Approaches for Collagen Quantification and Analysis

Multi-Method Approaches for Collagen Quantification and Analysis

The measurement of collagen can help researchers and physicians understand the pathological process of related diseases (such as osteoporosis, arthritis, skin aging etc.), and also aid in drug development and other biomedical research.The measurement of collagen can usually be carried out through several different methods:Mass Spectrometry1. ...

ByMtoZ Biolabs


Peptides for Osteoporosis Research

Peptides for Osteoporosis Research

Primary osteoporosis, including postmenopausal osteoporosis and senile osteoporosis. ...

ByBOC Sciences


Sacral Insufficiency Fractures in a Geriatric Patient Treatment with the Curvafix IM System - Case Study

Sacral Insufficiency Fractures in a Geriatric Patient Treatment with the Curvafix IM System - Case Study

Prior to the injury, the patient was a community ambulator; typically with a cane and occasionally with a walker. The patient had osteoporosis, hepatic failure with cirrhosis, and moderate ...

ByCurvaFix, Inc.


“Y” Shaped Sacral Fragility Fracture Treatment with the Curvafix IM System - Case Study

“Y” Shaped Sacral Fragility Fracture Treatment with the Curvafix IM System - Case Study

CASE PRESENTATION A 68-year-old female with some dysmorphism and mild osteoporosis had a fall in the shower, resulting in a Y-shaped sacral fracture and non-displaced fractures of the superior and inferior pubic ...

ByCurvaFix, Inc.


Introduction and Detection Methods for Phytochemicals

Introduction and Detection Methods for Phytochemicals

Classification and Functions of Common Phytochemicals Flavonoids Ÿ Species: Quercetin, brassin, catechin, lignan, anthocyanin, resveratrol Ÿ Functions: Anti-inflammatory, antibacterial, antioxidant, cancer prevention (breast cancer, ovarian cancer), lowering blood lipids and cholesterol Carotenoids Ÿ Species: Carotene, lutein, zeaxanthin, cryptoxanthin, capsaicin, lycopene Ÿ Functions: ...

ByCreative Proteomics


Rani is Opening Doors in Biosimilars, Challenging Humira and Others

Rani is Opening Doors in Biosimilars, Challenging Humira and Others

Another milestone for the company was initiating a Phase I clinical study of RT-102, a RaniPill capsule of teriparatide, a parathyroid hormone treatment for osteoporosis. The study focuses on the pharmacokinetics and safety of the drug. ...

ByRani Therapeutics


Treatment of Traumatic Shin Wound using CDO Therapy - Case study

Treatment of Traumatic Shin Wound using CDO Therapy - Case study

Patient: 72 year old female with a traumatic wound on left shin Age of Wound: 180 days Medical History: Altered mental/mobility, dementia, aphasia, anxiety, tremors, HTN, osteoporosis, A Fib, edema Previous Treatment: Moist wound therapy, TenderWet®, Aquacel®, Santyl® Treatment: OxyGeni® set at 5-8 ml/hr using an OxySpur® Diffusion Dressing Days on ...

ByEO2 Concepts


Proximal Femur Responses to Sequential Therapy With Abaloparatide Followed by Alendronate in Postmenopausal Women With Osteoporosis by 3D Modeling of Hip Dual-Energy X-Ray Absorptiometry (DXA)

Proximal Femur Responses to Sequential Therapy With Abaloparatide Followed by Alendronate in Postmenopausal Women With Osteoporosis by 3D Modeling of Hip Dual-Energy X-Ray Absorptiometry (DXA)

ABSTRACT Previous subgroup analyses from the ACTIVE trial in women with postmenopausal osteoporosis (NCT01343004) using three-dimensional (3D)-processing of dual X-ray absorptiometry (DXA) scans indicated greater increases in total hip cortical volumetric bone mineral density (Ct.vBMD) and estimated indices of hip strength following 18 months of abaloparatide (ABL) ...

By3D-Shaper Medical SL


Rani developing technology for oral delivery of injectable biologics

Rani developing technology for oral delivery of injectable biologics

TNF-alpha inhibitors for psoriatic arthritis. Parathyroid hormone for osteoporosis. Human growth hormone for its deficiency. And parathyroid hormone for hypothyroidism, a condition where the body produces abnormally low levels of the hormone, which regulates and maintains a balance of calcium and phosphorus. ...

ByRani Therapeutics


Design and R&D of Covalent Drugs

Design and R&D of Covalent Drugs

In addition, there is Odancate, which is used for the treatment of osteoporosis in postmenopausal women. However, due to its potential risk of stroke, Merck announced in 2016 that it would abandon this compound. ...

ByBOC Sciences


Rani Therapeutics’ $73M IPO will fund upcoming clinical trials

Rani Therapeutics’ $73M IPO will fund upcoming clinical trials

They include: Octreotide for acromegaly or neuroendocrine tumors in the GI tract (NETs) TNF-alpha inhibitors for psoriatic arthritis Parathyroid hormone (PTH) for osteoporosis Human growth hormone (HGH) for HGH deficiency Parathyroid hormone for hypothyroidism The product furthest along in the research cycle is the pill developed to administer octreotide (called ...

ByRani Therapeutics


Rani Therapeutics offers breakthrough capsule for patients with chronic conditions

Rani Therapeutics offers breakthrough capsule for patients with chronic conditions

The company plan to use the pill for a number of different conditions such as the growth hormone disorder acromegaly, diabetes and ...

ByRani Therapeutics


Rani Therapeutics prices $73M IPO for robotic drug-delivery pill tech

Rani Therapeutics prices $73M IPO for robotic drug-delivery pill tech

The appeal of a pill-based alternative to injectables could be especially great for patients on daily subcutaneous medicines such as teriparatide, an osteoporosis treatment often administered daily. The burden of injections limits the therapeutic potential of drugs like teriparatide, Imran said. ...

ByRani Therapeutics


Rani Therapeutics Debuts on the Nasdaq: What uou should know About the Biopharma

Rani Therapeutics Debuts on the Nasdaq: What uou should know About the Biopharma

Rani looks ahead to launching Phase 1 study of para thyroid hormone for the treatment of osteoporosis. The biopharma has ongoing clinical collaborations with Novartis AG NVS-0.01%+ Free Alerts, among others. ...

ByRani Therapeutics


Differential effects of abaloparatide and teriparatide on hip cortical volumetric BMD by DXA-based 3D modeling

Differential effects of abaloparatide and teriparatide on hip cortical volumetric BMD by DXA-based 3D modeling

Further studies are warranted to investigate how these differences affect therapeutic impact on hip strength in postmenopausal women with osteoporosis. Keywords: 3D modeling; Abaloparatide; Cortical volumetric BMD; Dual-energy X-ray absorptiometry; Osteoporosis; Teriparatide. ...

By3D-Shaper Medical SL


Effects of supervised high-intensity resistance and impact training or machine-based isometric training on regional bone geometry and strength in middle-aged and older men with low bone mass: The LIFTMOR-M semi-randomised controlled trial

Effects of supervised high-intensity resistance and impact training or machine-based isometric training on regional bone geometry and strength in middle-aged and older men with low bone mass: The LIFTMOR-M semi-randomised controlled trial

The Lifting Intervention For Training Muscle and Osteoporosis Rehabilitation for Men (LIFTMOR-M) trial was designed to compare the efficacy and safety of two novel, supervised, twice-weekly, high-intensity exercise programs in middle-aged and older men with osteopenia and osteoporosis on musculoskeletal health and risk factors related to falls and fractures. ...

By3D-Shaper Medical SL


Takeda Pharma GmbH, Germany - Case Study

Takeda Pharma GmbH, Germany - Case Study

Armin Groh, Laboratory Manager Quality Control Company / Institution Takeda Pharma GmbH, Germany Product lines NIRSolutions™ Industries Pharma & Biotech Customer: Takeda Pharma GmbH, Germany Takeda Pharma GmbH as part of the Japanese Takeda Group is a global pharmaceutical company, focussing on branded compounds as for gastroenterology, respiratory and infl ammation problems, ...

ByBUCHI


Could more sunshine make you less anxious?

Could more sunshine make you less anxious?

A paper published in the Mediterranean Journal of Clinical Psychology, Vitamin D status is associated with anxiety levels in postmenopausal women evaluated for osteoporosis, analysed the correlation between serum 25(OH) D (a hormone produced in the liver as a reaction to vitamin D) and anxiety levels. ...

ByPEAK Scientific Instruments Ltd


Effect of combined Low-Dose Radon- and Hyperthermia Treatment (LDRnHT) of patients with ankylosing spondylitis on serum levels of cytokines and bone metabolism markers: a pilot study

Effect of combined Low-Dose Radon- and Hyperthermia Treatment (LDRnHT) of patients with ankylosing spondylitis on serum levels of cytokines and bone metabolism markers: a pilot study

Ankylosing Spondylitis (AS) is a rheumatic disease and almost 50% of the affected patients suffer from osteoporosis. The ratio of Receptor Activator of Nuclear Factor κB Ligand (RANKL) and Osteoprotegerin (OPG) has become an important marker to assess the status of systemic bone metabolism and has been shown to be dysregulated in AS patients. ...

ByInderscience Publishers


Analysisof alendronicacidin pharmaceutical formulations

Analysisof alendronicacidin pharmaceutical formulations

This drug is used to prevent and treat osteoporosis as well as several other bone diseases. Alendronate Sodium is sold as tablets or solutions, alone or in combination with Vitamin D. ...

ByPickering Laboratories, Inc.

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