pathology system Articles
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Prevalence of pathologies in systems of systems
As system of systems engineering (SoSE) continues to mature and evolve as a field, there is a natural search for transcending themes and perspectives. The confluence of these themes and perspectives will serve to both distinguish as well as integrate the field. The purpose of this paper is to suggest advancement of the SoSE field by offering an emerging set of common systems–based pathologies ...
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Validation of a digital pathology WSI viewer - Case Study
This study presents a validation of the digital pathology system to assess the feasibility of remote slide review and evaluate the performance and usability of whole slide scanners and viewers. Pathologists at Memorial Sloan Kettering, a world leading cancer center, reviewed digitized whole-slide images, followed by a review of the same case on traditional glass ...
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Development of a Novel Encapsulated Non-Viral Cell- Based, BBB-Penetrant Therapy for MPS I
Introduction MPS I is caused by a deficiency of the lysosomal enzyme a-L-iduronidase (IDUA) leading to GAG accumulation in multiple tissues and organs This accumulation results in a complex array of progressive, multi-systemic pathologies, including CNS manifestations Approved therapies include enzyme replacement therapy (ERT), with chaperone and gene therapies under investigation Treatment ...
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Sustainability, Health, and the Human Population
A sustainable human population (e.g., range, density, and total numbers) is essential to health and in management. The notion of sustainability applies to all species and ecosystems and to the biosphere. Sustainability involves the health not only of individual humans, but also of ecosystems and other species. Thus, sustainability of the human population is important because of the wealth of ...
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Acibadem Hospitals Digital Pathology Project - Case study
Virasoft provides digital pathology systems that optimize the pathology workflow with digital slide management, slide viewing and quantitative image analysis for Acibadem Hospitals pathology laboratories. In partnership with Acibadem Hospitals and Virasoft, artificial intelligence projects are being developed for several cancer diagnosis. Digital Pathology System ViraCenter is an integrated ...
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Development of a Novel Encapsulated Non-Viral Cell-Based, BBB-Penetrant Therapy for MPS I
MPS I is caused by deficiency of the lysosomal enzyme a-L-iduronidase (IDUA) leading to GAG accumulation in multiple tissues and organs This accumulation results in a complex array of progressive, multi-systemic pathologies, including CNS manifestations Approved therapies include enzyme replacement therapy (ERT), with chaperone and gene therapies under investigation Treatment with approved ...
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Limits of Stability - The most used protocol for balance assessment
The Limits of Stability (LOS) is perhaps the most used protocol in the literature for balance assessment in a dynamic task. It quantifies the ability to intentionally displace the center of gravity to the patient’s stability limits without losing balance. This protocol provides information regarding voluntary motor control, which also helps screening fall risk in elderly people [1]. How ...
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Teleradiology in Covid-19
The start of coronavirus pandemic pushed limits of healthcare systems all over the world by causing thousands of deaths and the requirement of a huge quantity of healthcare resources. When WHO declared COVID19 as a pandemic, the whole world came to standstill. Half of the world population is confined to their home except for essential services. In the year 2016, when GOI announced ...
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Improving Health in Ucayali, Peru: A Multisector and Multilevel Analysis
We review the key determinants of health in Ucayali, Peru, identified by researchers, and, according to these, propose a set of tools to improve health in this area. Women and indigenous peoples are recognized as two vulnerable groups in the region that face greater health risks, and these are the main focus of the development of tools for health improvement. Also, the growing economic ...
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Reversing the Psychiatric Effects of Neurodevelopmental Cannabinoid Exposure: Exploring Pharmacotherapeutic Interventions for Symptom Improvement
Abstract: Neurodevelopmental exposure to psychoactive compounds in cannabis, specifically THC, is associated with a variety of long-term psychopathological outcomes. This increased risk includes a higher prevalence of schizophrenia, mood and anxiety disorders, and cognitive impairments. Clinical and pre-clinical research continues to identify a wide array of underlying neuropathophysiological ...
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Chemyx Syringe Pumps in Neuroscience Research
Introduction The classical field of neuroscience entails biological or psychological investigation of the nervous system, including the brain, spinal cord and the systemic network of sensory nerve cells called neurons.1 Traditionally, this field comprised of purely biological studies but has since flourished into an interdisciplinary sphere addressing the developmental, physiological, ...
By Chemyx Inc
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The Role of Lactate in Sepsis Research
Sepsis reportedly affects up to 30 million people each year. Lactate levels play a key role in diagnosing the condition and limiting its impact, as well as researching it's progression and developing possible treatments. Here's how. Sepsis is a medical condition and emergency, the definition of which has proven difficult and is based on fairly recent developments and research. It is the result ...
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High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue
Highlights Deterministic barcoding in tissue enables NGS-based spatial multi-omics mapping DBiT-seq identified spatial patterning of major tissue types in mouse embryos Revealed retinal pigmented epithelium and microvascular endothelium at cellular level Direct integration with scRNA-seq data allows for rapid cell type identification Summary We present ...
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