patient clinical Articles
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First patient inclusion of the METAglut1 study
The METAglut1 study is a prospective study to validate the diagnostic performance of the METAglut1 test in patients clinically compatible with GLUT1 Glucose Deficiency Syndrome (GLUT1-DS) or « DE VIVO Disease ».It will be conducted in about 40 French centers and plans to include between 2500 and 3000 patients over a period of 30 months. This study has received the support of the ...
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Dynamic process modelling of patients` no-show rates and overbooking strategies in healthcare clinics
Abstract: Clinic appointment cancellation and 'no-shows' by patients can disturb day-to-day scheduling and lead to inefficient resource allocation and lost revenue. This paper presents an approach for dynamic process modelling and analysis of patients' no-show rates in conjunction with the overbooking strategy. To this end, a dynamic discrete event simulation model of a clinic operation is ...
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Dynamic process modelling of patients' no–show rates and overbooking strategies in healthcare clinics
Clinic appointment cancellation and 'no–shows' by patients can disturb day–to–day scheduling and lead to inefficient resource allocation and lost revenue. This paper presents an approach for dynamic process modelling and analysis of patients' no–show rates in conjunction with the overbooking strategy. To this end, a dynamic discrete event simulation model of a clinic ...
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Lehigh Valley Health Network: External Beam Electron Treatment with 3D Printed Modulated and Simple Bolus - Case Study
This patient case demonstrates the clinical application of Adaptiiv’s technology used in radiation oncology through the design and fabrication of both modulated and uniform thickness (simple) ...
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Drug adherence in Parkinson`s disease
Abstract Physicians modify drug schedules in response to their patients' clinical responses. Failure to relieve patients' symptoms or the emergence of drug-related side effects may reflect nonadherence to a prescribed drug schedule rather than incorrect therapeutic physician decisions. Using a medication questionnaire and a computerized medication event monitoring system (MEMS) to monitor ...
By Sensidose AB
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Anti-HIV and anti-inflammatory action of iodine-lithium-α-dextrin is accompanied by the improved quality of life in AIDS patients
Clinical efficacy, tolerability and safety of various doses of Iodine-Lithium-α-Dextrin (ILαD) monotherapy have been evaluated in 56 HIV-infected patients enrolled in double blind uncontrolled randomised study during 48 weeks follow-up period. ILαD was administered intravenously three times over five days with intervals of 23 weeks between treatments for a total of 12 infusions in 4 cycles. HIV-1 ...
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The QUEST Post-Amputation Pain Study - Case Study
The QUEST study (High-FreQUEncy Nerve Block for PoST-Amputation Pain), is a randomized controlled study of 180 patients at 25 clinical study sites in the U.S. Recruitment for the study was completed in late 2021. Results are blinded until after participants have finished a twelve-month follow-up. ...
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PPI Use may Not Prevent High-grade Dysplasia and Oesophageal Adenocarcinoma in Barrett’s Oesophagus: A Nationwide Study of 9883 clinical Patients
Hvid-Jensen F, Pedersen L, Funch-Jensen P, Drewes A. Aliment Pharmacol Ther. 2014 May;39(9):984-91. OBJECTIVES: To investigate if the intensity and adherence of PPI use among all patients with BO in Denmark affected the risk of oesophageal adenocarcinoma. RESULTS: We identified 140 cases with incident oesophageal adenocarcinomas and/or high-grade dysplasia, with a median follow-up time of 10.2 ...
By Restech
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What makes decentralisation the future of clinical trials?
With the emergence of COVID-19, Decentralisation of Clinical Trials became necessary to comply with social distancing requirements while carrying out clinical research. Over the past few years, the clinical trial landscape has shifted its focus to patient-centric practices to promote patient engagement. But now as the pandemic is long gone, it is time to reflect on how DCT studies are genuinely ...
By Clinion
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TAILOR-PCI Proves Genotype-guided Antiplatelet Therapy Reduces MACE
TAILOR-PCI was a 7-year 5,300-patient clinical trial of precision medicine for cardiac stent patients, funded by Mayo Clinic and the National Institutes of Health (NIH). Genomadix’s FDA-cleared rapid RX CYP2C19 genotyping test was used to personalize antiplatelet therapy with clopidogrel or ticagrelor. The results were published on August 25, 2020 in the Journal of the American Medical ...
By Genomadix
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Clinical significance of low-dose radiation therapy: radiation hormesis
This study was designed to investigate the clinical significance of low-dose radiation therapy, radiation hormesis, and accuracy of therapeutic regimen. Radiation hormesis was performed in six patients (four patients with malignant diseases and two patients with benign diseases) in the experimental room where they could be exposed to a low level of direct gamma ray and inhale radon gas ...
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Biorep Innovation Partner to COVID-19 Stem Cell Therapy Trial
After a lightning round of proposals and reviews, an international team of scientists led by Dr. Camillo Ricordi was granted immediate FDA authorization for a 24-patient clinical trial to test the safety and exploratory efficacy of umbilical cord-derived mesenchymal stem cells (UC-MSCs) to block the life-threatening lung inflammation that accompanies severe cases of COVID-19. The therapy uses ...
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The monocyte dysfunction induced by acute tetramine poisoning and corrected by continuous blood purification
The monocyte function of patients with severe tetramine poisoning and the effects of sequential hemoperfusion (HP) and continuous veno-venous hemofiltration (CVVH) on the immune status of the patients were investigated. Eleven patients with severe acute tetramine poisoning were treated with sequential HP and CVVH. The APACHE II score and Glasgow score were used to evaluate the disease status ...
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The latest developments of Medis QFR
December 2022 edition Given the regular posts of peer-reviewed scientific publications on the Medis QFR®, it is clear that this angio-based solution for coronary physiology is extensively used in clinical research and practice. We would like to share these publications with you so that you remain up to date about the research that is ongoing worldwide with this innovative solution, ...
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Minimally Invasive Stretta Therapy Gains Momentum as HCSC BCBS Adds Coverage for 16 Million New Patients
We’ve all been there. In our doctor’s office, or on the phone with their billing manager, being told that a drug or procedure we hoped for is not covered by our insurance plan. After weeks or even months of researching online, talking to other patients, and comparing alternatives, we’ve been told that our insurance plan simply will not cover that solution. Our frustration is ...
By Restech
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Winback Energy: the power in your hands
The world is in the midst of a pandemic and the economic woes are being felt around every corner, including our patients and our clinics. Times are changing and consumer patterns will forever be altered. Gone are the times of densely crowded waiting rooms to see the doctor! Enter, the “boutique” style clinic that sees less patients, provides superior cleanliness and gets faster more ...
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Nanostics Re-Opens ClarityDX Prostate Clinical Study with New US Recruitment Site
Summary Nanostics' clinical validation study for ClarityDX Prostate, a liquid biopsy test for the early diagnosis of clinically significant prostate cancer, re-opens recruitment after lifting of COVID-19 research restrictions A top-ranked research institute in the Northeast US will now partner with Nanostics' by recruiting patients for the clinical validation study This partnership will ...
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How eCOA Improves Patient Experience and Data Quality
With the rising demand for improving patient safety in clinical trials, the adoption of patient-centric solutions is considered the best route to enhance data accuracy and experience automated workflows. This is where eCOA comes into play. In this blog post, we will find out how electronic clinical outcome assessments are helping the clinical trials industry handle the ever-growing list of ...
By Clinion
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Shot in the arm for wearable drug delivery system
Enable ultimately aims to increase healthcare provider efficiencies, minimise patient exposure in the clinic, and reduce healthcare costs, with the aim of benefiting patients and healthcare providers worldwide. CEO and president Mike Hooven said the funding: “will help enFuse continue to redefine intravenous drug delivery by meaningfully scaling our development and commercialisation ...
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Nanostics is Developing and Validating a Simple Blood Test to Predict Severity of COVID-19 Disease in SARS-CoV-2 Positive Patients
Edmonton, Alberta - Nanostics Inc., a diagnostic healthcare company that focuses on developing tests to determine a patient's disease risk, announced today plans to develop and validate ClarityDX COVID-19; a simple blood test to predict the severity of COVID-19 disease in patients. Nanostics, in collaboration with the Canadian BioSample Repository (CBSR) at the University of Alberta and Century ...
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