patient population Articles
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Open-Source AI Platforms: Driving Success through Diversity
Digital biomarkers can open a world of possibilities in understanding the nuances of a patient’s behavior and response to treatment. Rather than relying on subjective perceptions of how a patient is responding, digital biomarkers treat patient observation more like an engineering problem. Such precise, sensitive measurements can ultimately influence the future of a patient’s care plan ...
By AiCure
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Indication selection for anti-PDx combination therapy In collaboration with big pharma - Case Study
The Challenge: One of the most common challenges in immuno-oncology is identifying the indications and patient populations that would benefit from a specific therapy, especially on top of Standard of Care (SOC) treatments. Our platform tackled this challenge of indication prioritization and patient stratification for a combination of a specific target (A) with an anti-PDX drug that one of our ...
By CytoReason
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Adoption of medical technology by hospitals: a review of innovation attributes and a conceptual model of the resulting service
Innovative medical technologies help to transform health care by empowering physicians and patients with tools that enable faster diagnosis and better treatment of disease. Diagnostic practices and procedural functions in clinics and surgeries are dependent on modern instruments, tools and laboratory equipment. This paper examines innovation attributes in detail and discusses their implications ...
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Good Machine Learning Practice: The First Step Toward Transparency & Trust
Machine learning (ML) innovation in healthcare is growing, and the oversight on its development should keep pace to ensure it’s developed in a scientifically sound, safe way. Just as the FDA requires detailed ingredients on the side of cereal boxes to help consumers make informed health decisions, the same transparency should apply to the ML technology our patients and clinicians use every ...
By AiCure
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What dermatologists need to know about Bartonella
Galaxy Diagnostics co-founder Dr. Ed Breitschwerdt on ReachMD with Dr. Michael Greenberg on what dermatologists should know about Bartonella species infections. Research over the past 30 years has shown that Bartonella species infect a wide array of cell types, including red blood cells and endothelial cells (in particular cells that line the blood vessels), in both people and ...
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OneThree’s Workflow for Identifying Synergistic Drug Combinations - Case study
Background OneThree Biotech was born out of the largest precision medicine institute in America with the purpose of decreasing the failure rate of bringing therapeutics to market using biology driven artificial intelligence. Our technology was builtin a lab setting; allowing us to engineer our methodologies around real-world results. While working with major biotech and pharma partners; ...
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Big, Small & Wide: Combining Old and New Data Approaches to Advance Precision Medicine
For decades, data scientists and AI developers have typically followed the belief that “bigger is better” – the bigger the data set, the more analytical freedoms one has, and the more insights one gains. The AI industry still heavily relies on big data analytics, and for good reason – we need to feed AI large amounts of high quality, diverse data to ensure it works ...
By AiCure
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Navigating Cancer in Collaboration with Experts in Oncology Present Key Research at 2022 ASCO Annual Meeting on Using Digital Health Solutions to Bridge the Health Equity Gap
Navigating Cancer in collaboration with Texas Oncology executes large-scale patient engagement study revealing high digital health solution engagement while demonstrating the opportunity to increase support for diverse patient populations. Scientific and technological advancements have helped enhance cancer care and access to care. Indeed, an important silver lining in the pandemic has been the ...
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Cells isolated from donors with nonalcoholic fatty liver disease exhibit disease phenotypes in 3D bioprinted human liver tissue
Publication Summary: The identification of targets and biomarkers and development of therapeutics for nonalcoholic fatty liver disease (NAFLD) may be accelerated by the use of well-characterized primary cell and tissue reagents, as well as improved in vitro human cell-based disease models, including three-dimensional (3D) bioprinted liver tissue. The characteristics of donors from which the ...
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Rational Vaccines Announces a Clinical Trial to Determine Baseline Characteristics of Patients Diagnosed With Recurrent Symptomatic Herpes Simplex Type 2 (HSV-2) Virus
Study to be conducted at two leading research institutions in the U.K. Results will inform protocol design of Phase 1/2 clinical trial of Company's lead HSV-2 therapeutic vaccine candidate WOBURN, Mass. and OXFORD, England, Aug. 15, 2022 /PRNewswire/ -- Rational Vaccines, a company focused on revolutionizing the treatment and prevention of herpes to eradicate the disease, today announced the ...
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Mitigating Bias in AI: Holding Innovation to a Higher Standard
When it comes to building equitable, quality AI, prioritizing diverse data sets needs to be embedded in a developer’s DNA – rather than a “nice to have,” it should be a deliberate framework in which AI is built. Before deploying an algorithm to patients, it should be rigorously evaluated under both common and rare scenarios to ensure it performs as intended and ...
By AiCure
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OneThree`s Workflow for Target and Compound Discovery - Case study
Background OneThree Biotech was born out of the largest precision medicine institute in America with the purpose of decreasing the failure rate of bringing therapeutics to market using biology driven artificial intelligence. Our technology was builtin a lab setting; allowing us to engineer our methodologies around real-world results. While working with major biotech and pharma partners; ...
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From Black Box to Transparency: Pulling the Curtain Back on Machine Learning
The introduction of Good Machine Learning Practices (GMLP) and increasing buzz around the need for transparency and standardization of machine learning (ML) are significant steps to encourage adoption and trust in these tools across the healthcare industry. To do so, though, requires shifting these ideals from mere concepts into actionable processes without setting an unrealistic bar for ...
By AiCure
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Results support feasibility of entirely extracardiac, minimally invasive, temporary pacing system
New results support the feasibility of an entirely extracardiac pacing method in a heterogeneous patient population, using a minimally invasive, parasternal delivery approach, with adequate sensing and thresholds suited for temporary pacing. The study, authored by Anne-Floor BE Quast, Niek EG Beurskens (University of Amsterdam, The Netherlands) and colleagues, was recently published in ...
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Glooko Adds New Enhancements to Billing Export Feature to Streamline Submitting CPT Codes for Remote Patient Monitoring Reimbursement
Glooko recently introduced new enhancements to the billing export feature in Population Health Analytics for professional users with Glooko Enterprise accounts. The new features provide healthcare providers and care teams supporting patients with diabetes and related chronic conditions the information needed to properly bill CPT codes for remote patient monitoring (RPM) activities. This ...
By Glooko, Inc.
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Clinical CRISPR Success Demonstrates Need for Quality Control
The Clinical CRISPR Successes Are Stacking Up. But Where’s the Emphasis on Quality Control? In mid-September, Intellia released some promising data on two of their CRISPR-based therapeutics. These results are a significant milestone for genome editing and validation of its effectiveness in the clinic. However, the safety of CRISPR-based therapeutics has been a major concern and part of a ...
By CRISPR QC
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New DVT device completes first-in-human trial (Venous News)
The first-in-human case using the new deep vein thrombosis (DVT) device Vetex thrombectomy catheter (Vetex Medical) has recently been completed in a multicentre study. The device has the potential to reduce hospital stays and costs associated with DVT treatment, a press release announces. According to Vetex Medical, the Vetex thrombectomy catheter is the first device to combine rotational and ...
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5 Key Takeaways about Remote Patient Monitoring from HIMSS22
HIMSS22 was filled with collaboration, especially about RPM. Here are five key takeaways from Team Glooko.#1: The key to achieving RPM success is ease of use. Ease of use is key when it comes to RPM success. There has been a proven sustained reduction in HbA1c with Glooko RPM for patients with type 2 diabetes, which shows how imperative it is to have an easy-to-use solution for both patients and ...
By Glooko, Inc.
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Targeted Therapy of Intracellular Oncoproteins by Peptide-centered CAR T Cells
Researchers at the Children's Hospital of Philadelphia (CHOP) have made a breakthrough in the treatment of aggressive solid cancers, and they have developed a new cancer treatment that targets proteins within tumor cells that are essential for tumor growth and survival, but this has not been possible before. Using the power of large data and advanced computational methods, researchers can ...
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From Predicting Adherence to Health Outcomes – The Power of Predictive Insights
Clinical researchers have begun adopting predictive analytics to anticipate a patient’s engagement in a clinical trial, including if and how a patient will adhere to their treatment plan. As these models are fed more patient-level audio and visual data, they have the potential to open up a whole new world of a patient’s lived experience – from how a patient will respond to their ...
By AiCure
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