patient response Articles
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Drug adherence in Parkinson`s disease
Abstract Physicians modify drug schedules in response to their patients' clinical responses. Failure to relieve patients' symptoms or the emergence of drug-related side effects may reflect nonadherence to a prescribed drug schedule rather than incorrect therapeutic physician decisions. Using a medication questionnaire and a computerized medication event monitoring system (MEMS) to monitor ...
By Sensidose AB
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Changes in MRE in HCV patients who achieve SVR
Abstract Almost all patients achieved sustained virological response (SVR) by direct-acting antivirals (DAA) therapy, but it is not clear as to what extent DAA therapy affects changes in liver fibrosis after achieving SVR. In this study, we investigated the changes of liver stiffness by magnetic resonance elastogaraphy (MRE) during DAA therapy. A total of 308 patients were enrolled in the study. ...
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More Careful Scrutiny Encouraged for Purification and Quantitative Testing of Nutritional Supplements
Recent case of selenium toxicity points to need for FDA to toughen regulations for supplements. MacFarguhar et al have written an excellent article in the Feb. 8, 2010 edition of the Archives of Internal Medicine entitled “Acute Selenium Toxicity Associated with a Dietary Supplement.” They report that in 2008 a chiropractor in Florida noted common symptoms of gastrointestinal illness ...
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Surgeon perception is not a good predictor of peri-operative outcomes in robot-assisted radical prostatectomy
Abstract Surgeons have always used their cognitive intuition for the execution of skilled tasks and real-time perception of intra-operative outcomes. We attempted to measure the overall accuracy of intra-operative surgeon perception on the functional outcome of early continence after robot-assisted radical prostatectomy (RARP). A single experienced surgeon (D.I.L.) used a scoring sheet to ...
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New treatment methods are needed to help in mental health crisis
Saturday the 10th of October is World Mental Health Day. It provides an opportunity to talk about the work related to mental health, and what needs to be done to make mental health care accessible for more people. This year, especially due to COVID-19, there is more need for this than ever. The pandemic has been increasing the need for mental health care. According to a recent study, ...
By Nexstim Plc
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Laser therapy offers pill-free foot pain relief
Sharon Whitt is settling in for a 10-minute treatment that she credits with getting the spring back in her step. “I like to dance, so that makes it a lot more comfortable to dance and not so much pain and pressure on the foot area,” she explains. Whitt was diagnosed with Morton’s Neuroma four years ago. It is a painful condition affecting nerves on the ball of the foot. ...
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Revenue Cycle Management Challenges and Landscape
As leadership continues to look for revenue cycle management teams to make improvements, there are continued pressures in healthcare to identify cost efficiency opportunities and generate stronger cash flows. Between ICD-10, accountable care and other regulations it is in the hospital’s best interests to have effective revenue cycle management systems to meet financial pressures and ...
By ElementBlue
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Hospital noise levels are getting worse
Noise pollution from medical equipment, alarms, phones, doors opening and closing, staff activities and visitors can make hospitals and especially intensive care units very noisy places. Add to that the amount of hard reflective surfaces and how close beds are to each other and you’ve got an acoustically unpleasant environment where noise bounces around and gets amplified. Anyone who has ...
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Bridging Clinical Research to Real-World Patient Care Through Predictive Analytics
The ability to predict how a clinical trial participant will adhere to their treatment, and even respond to that treatment, has great promise to advance patient-centric clinical research. But, as we look to understand the impact a drug has on patients’ everyday health outside of a research environment, what happens to these unique, predictive findings around dosing and outcomes once a drug ...
By AiCure
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Baroreflex Activation Therapy: A Novel Approach for HFrEF Patients
During the webinar, you’ll learn about: Treatment options and unmet needs of HFrEF patients The physiologic rationale of baroreflex activation Barostim therapy overview and clinical evidence overview Appropriate patient selection and real-world experience Important Safety Information CAUTION: Federal law restricts this device to sale by or on the ...
By CVRx
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Arrhythmia - Atrial Fibrillation (AF)- Case Study
Atrial Fibrillation (AF) is often described as an irregularly irregular rhythm. AF is an arrhythmia with no consistent ventricular response or pattern due to its somewhat random and chaotic discharging of atrial impulses firing disconnectedly from multiple foci. This continuous and erratic behavior results in a ventricular response that changes from beat to beat. AF will typically present with a ...
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Delivering a precision medicine programme at scale
The Covid-19 pandemic highlighted the disparity between those who succumbed to severe illness while others remained relatively unaffected, underscoring the urgent need to shift the healthcare industry’s focus from a one-size-fits-all approach to more personalised healthcare. Personalised medicine promises to transform healthcare with treatments tailored to a patient’s unique genetic ...
By Lifebit
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Going beneath the surface of skin cancer - Case study
Summary In this Cell Patterns publication, Ozette co-founders and collaborators at the Cancer Immunotherapy Trials Network (CITN) outline a novel method of analysis of single cell data, FAUST, and validate the multiple potential applications. The paper tackles 2 important problems: 1) analysis of complex single cell datasets; 2) prediction of response to immunotherapy in cancer. Manual ...
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Drug Delivery: What do Patients and Providers Want?
Citation: Huddleston M, Estep J, “Drug Delivery: What do Patients and Providers Want?” ONdrugDelivery, Issue 124 (Sep 2021), pp 10–14. Matthew Huddleston and Jennifer Estep discuss current drug delivery options and the value of convenient care. Worldwide, patient and provider preferences are changing due to the covid-19 pandemic. The need to reduce patient exposure to the ...
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Driving Data-driven Medicine to Advance Personalized Care
Clinical trials are often designed with the participant’s everyday life in mind – trying to gather as much clinically-relevant data in a controlled manner as possible while allowing individuals to live their regular lives. However, it is true that trials are artificial environments, and participants are actively monitored to ensure their safety and to determine the efficacy of a drug ...
By AiCure
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CD Genomics Perspective: RNA Sequencing, A Powerful Method for Studying Various Diseases
Although post-mortem brains have been frequently reported as the "gold standard" in transcriptomic research for ND and neuropsychiatric abnormalities, the main sources has been mRNA separated from transgenic animal models and, more lately, patient-derived cell lines. However, despite their promise, transcriptome studies are difficult due to the obvious difficulties in obtaining brain tissue and ...
By CD Genomics
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Establishment of a Stable Organoid Culture System: Customization and Standardization
Prefix Organoids are miniature organs created in vitro from adult stem cells (ASCs) or pluripotent stem cells (PSCs). They form three-dimensional (3D) tissue-like structures through the self-organization, self-renewal, and differentiation capabilities of stem cells. Compared to traditional two-dimensional (2D) cell cultures or spheroids, organoids closely resemble living organs in terms of ...
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Applications of Single-Cell RNA Sequencing in Drug Discovery and Development
Advantages of Single-Cell RNA Sequencing in Drug Discovery Single-Cell RNA Sequencing (scRNA-seq) offers several advantages in drug discovery, primarily through target identification. By analyzing complex tissues and diseases at the cellular level, scRNA-seq allows researchers to identify distinct cell subtypes and their gene expression profiles. This knowledge enhances our understanding of ...
By CD Genomics
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Oxygen therapy for neurology
A prematurely aged brain has suffered years of abuse from our ever-increasingly toxic environment and unhealthy lifestyles. There is extensive research that shows HBOT may have an effect in rejuvenating a patient’s brain by stimulating the production of new blood vessels. Increased oxygen in the blood flow will re-energize dormant cells in the brain and create new ones. Oxygen to ...
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Breaking Barriers – Past and Current: Celebrating the Legacy of Dr. Clarice Reid, Pioneer in Sickle Cell Research, Biomark Diagnostics
Dr. Clarice Reid was a trailblazer in the field of sickle cell disease, dedicating her life and career to improving the lives of those affected by this debilitating genetic blood disorder. As a pioneering black woman in the field of medicine and science, Dr. Reid’s work has made a significant impact on our understanding of this condition and has paved the way for the development of ...
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