patient sample Articles
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Morbidity pattern of pulmonary tuberculosis and housing quality in Lagos metropolis, Nigeria
The intractable problem of tuberculosis (TB) control despite advances in chemotherapy requires additional research effort to unravel the pertinent factors that make the disease preponderant in developing countries. The present study examined the pattern of TB morbidity in Lagos metropolis with the aim of identifying the explanatory factors. Data on reported cases of pulmonary TB were collected ...
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Infrared spectroscopy of human bone marrow: evidence of structural changes during acute leukemia
Fourier transform infrared (FTIR) spectroscopy was explored as a means to distinguish newly diagnosed of acute lymphoblastic leukemia from disease free bone marrow samples. Characteristic bands alterations were identified in both healthy and diseased samples arising from cellular protein, lipid and DNA. There were specific changes that affected the secondary structure of proteins that appeared in ...
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Medical-Grade Refrigeration for Storage and Transport
All You Need To Know About Medical-Grade Refrigeration Units For Pharmaceutical Storage And Transport One of the pillars for a successful healthcare system is the stable maintenance of vaccines, medications, reagents, and patient samples. These tend to be time- and temperature-sensitive. Vaccines and medicines are transferred through a cold chain from creation up to the time it is administered ...
By AKCP
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Employee Spotlight: Dr. Gerald Martin
Understanding the human genome has opened up incredible new possibilities for health. As experts in this complex field, we lead the way in bringing genomic insights into patient care so communities anywhere can benefit. Our employee spotlight shines the light on Gerald Martin, Senior Field Application Scientist. What is your educational background? I have a BA Honours degree from Trinity ...
By PierianDx
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The Secret to Removing 90% of Moisture from a Patient’s Breath Sample
Breath has lots of moisture. To see, just blow on a mirror and watch it fog up. Getting rid of the moisture on the mirror is easy: just wipe it off. Getting rid of moisture in a breath sample is more complex, but can be done with a bit of engineering and Nafion™ tubing. We have found ways to remove up to 90% of moisture from a patient’s breath sample. Moisture: Why You Need it Gone? ...
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How the Breuer Lab tracks their sample information at every step of their research
Dr. Eun-Kyoung Breuer is an Assistant Professor and an Associate Director of the Radiobiology Program in the Department of Radiation Oncology at Loyola University Chicago. Her lab's research focuses on understanding the role that tumor suppressor genes play in the DNA damage response pathway and in breast cancer regulation. A centralized information management approach Doing research focuses on ...
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Single-Cell RNA Sequencing in Drug Discovery and Development
What Are the Advantages of Single-Cell RNA Sequencing? One of the significant advantages of scRNA-seq in drug discovery is its impact on target identification. By allowing researchers to dissect complex tissues and diseases at the cellular level, scRNA-seq enables the identification of distinct cell subtypes and their gene expression profiles. This information can lead to a better understanding ...
By CD Genomics
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Applications of Single-Cell RNA Sequencing in Drug Discovery and Development
Advantages of Single-Cell RNA Sequencing in Drug Discovery Single-Cell RNA Sequencing (scRNA-seq) offers several advantages in drug discovery, primarily through target identification. By analyzing complex tissues and diseases at the cellular level, scRNA-seq allows researchers to identify distinct cell subtypes and their gene expression profiles. This knowledge enhances our understanding of ...
By CD Genomics
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Breaking Down Barriers: How Enzymes are Revolutionizing Research and Diagnostics
Enzymes play important roles in research and diagnostic applications. Enzymes are natural biological catalysts that accelerate the rate of biochemical reactions, and they are widely used in many different fields. In this article, we have discussed the applications of enzymes in research and diagnostics, as well as some of the most common enzymes used. Enzymes have a wide range of applications ...
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Nanostics is Developing and Validating a Simple Blood Test to Predict Severity of COVID-19 Disease in SARS-CoV-2 Positive Patients
Edmonton, Alberta - Nanostics Inc., a diagnostic healthcare company that focuses on developing tests to determine a patient's disease risk, announced today plans to develop and validate ClarityDX COVID-19; a simple blood test to predict the severity of COVID-19 disease in patients. Nanostics, in collaboration with the Canadian BioSample Repository (CBSR) at the University of Alberta and Century ...
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Clinical Research On-Demand: How the University of Washington’s Theberge Lab is Using Tasso to Study Unpredictable Events in Real Time - Case Study
Many important research questions cannot be studied under controlled circumstances. Events like natural disasters or disease exposure often occur without warning and prevent in-person clinic visits, making timely observation difficult without a flexible approach. At the University of Washington, researchers are partnering with Tasso to study these scenarios by deploying on-demand remote ...
By Tasso, Inc.
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Nanostics Re-Opens ClarityDX Prostate Clinical Study with New US Recruitment Site
Summary Nanostics' clinical validation study for ClarityDX Prostate, a liquid biopsy test for the early diagnosis of clinically significant prostate cancer, re-opens recruitment after lifting of COVID-19 research restrictions A top-ranked research institute in the Northeast US will now partner with Nanostics' by recruiting patients for the clinical validation study This partnership will ...
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Structural and functional changes in cardiovascular system at arterial hypertension in persons exposed to ionising radiation
The purposes of this research were: (1) to carry out the comparative evaluation of indices of the morphofunctional condition of the cardiovascular system (CVS) in patients with arterial hypertension (AH) exposed to ionizing radiation, taking into account the occurrence of peripheral arterial atherosclerosis and the spread of traditional risk factors of cardiovascular diseases (CVD); (2) to ...
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Bartonella quintana: Putting the re-emerging in emerging infection
Introduction Trench fever was a defining feature of World War I. Notables like A.A. Milne, author of Winnie-the-Pooh, and fantasy writer JRR Tolkien were treated for trench fever. But surely trench fever did not just appear in the European trenches of World War I and then disappear after. What’s the rest of the story? Before World War I, Way Before While infections caused ...
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AXIM Biotech chooses the iPeak for the Dry Eye Disease Diagnostics
Founded in 2014 in California, AXIM® Biotechnologies, Inc. is a vertically integrated research and development company focused on improving the landscape for diagnosis of ophthalmological conditions such as Dry Eye Disease (DED) through rapid diagnostic tests. Additionally, it owns IP and has conducted research on SARS-CoV-2 (COVID-19) rapid neutralizing antibody tests to detect ...
By IUL S.A.
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Enzyme for Diagnosis: Revolutionizing Medical Diagnostics
Enzymes are biological catalysts that accelerate chemical reactions in living organisms. In recent years, enzymes have been increasingly utilized in medical diagnostics, leading to significant advancements in disease detection and management. Enzyme-based diagnostic tools have revolutionized the healthcare industry, offering numerous benefits such as increased accuracy, sensitivity, and speed. ...
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Innovative Diagnostic Development Urges Rare Disease Therapies
Rare diseases are characterized by their low prevalence, affecting a small number of people across the world. These diseases often come with significant challenges, including accurate diagnosis, availability of effective treatments, and limited resources for research and development. However, recent advancements in diagnostics technology hold promise for speeding up the field of rare disease ...
By Protheragen
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Viable SARS-CoV-2 Delta variant detected in aerosols in a residential setting with a self-isolating college student with COVID-19
Highlights Viable Delta Variant SARS-CoV-2 collected from air samples in a residential environment. SARS-CoV-2 detected in an area of a single-family dwelling distant from an isolation suite occupied by COVID-19 patient. Assessment of air samples and surface swab samples by rRT-qPCR and cell culture for SARS-CoV-2. Employment of air samplers functioning based on different collection ...
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Unveiling Gene Isoforms by RNA Sequencing: Detection Methods and Applications
What Is Gene Isoform? Gene isoforms are different variations or versions of a gene that can be produced by alternative splicing or alternative transcription initiation and termination. These isoforms are often present in the same organism or cell type but differ in their coding sequence or in the regulatory elements that control their expression. Alternative splicing is a process in which ...
By CD Genomics
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High Throughput SHERLOCK CRISPR SARS-CoV-2 Test
Abstract: The ability to control the spread of COVID-19 has been hampered by a lack of rapid, scalable, and easily deployable diagnostic solutions. Efforts to increase testing capacity have been adversely impacted by supply chain challenges due to dependencies on a limited set of reagents, consumables, and instrumentation. Here, we present a diagnostic method based on CRISPR (clustered regularly ...
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