patient specific Articles
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Using Go!SCAN 3D Scanner for the Individualized Orthopetic Development in Medical Technology
The laboratory for additive manufacturing (LaF) at Landshut University, deals with the process of reverse engineering headed by Prof. Dr.-Ing. Norbert Babel. This includes scanning objects, scanning data processing using special software tools and transfer to a CAD system, modeling and simulating, as well as generating prototypes developed which are manufactured with different additive ...
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Do You Have Processes in Place to Comply with USP <797>?
Hospital central fill facilities and individual hospitals will soon need to comply with the updated USP guidelines. While the regulation is not yet in place, it’s important to have a plan in place for your organization. In the event of an accreditation survey or audit, would you be in compliance with the updates today? Master Formulation Record As part of the updated USP General ...
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Chest CT Segmentation - Case study
The challenge An industry-leading medical device company required the capability to automatically generate an accurate 3D model of complex patient-specific anatomies The anatomical model was needed for planning challenging surgical navigation procedures The pre-existing solution was slow and not robust, requiring extensive and time-consuming manual editing by the interventionist Our ...
By RSIP Vision
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During this Season of Giving-Consider the Ultimate Gift of Passion for Humanity
Unfortunately, despite a considerable increase in organ donations during the current pandemic the need for donor organs still far outpaces donations. All too many patients continue to wait for a life-saving organ transplant. Currently more than 106,000 men, women and children sit on the transplant waiting list in the US. And there are countless more whose life could be saved who are not even ...
By BIOLIFE4D
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Predicting cardiotoxicity with engineered 3D human cardiac tissue models
Cardiovascular safety liabilities caused 52.3 % of 44 marketed data from 1980 to 2011, and cardiovascular disease remains the leading cause of death globally, yet only 8.7% of cardiovascular drugs successfully pass clinical trials. These statistics demonstrate the need to address a patient’s specific genetic make-up and phenotype by adopting a personalized treatment methodology for ...
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World’s First aprevo Personalized Spine Surgery Performed Using the Only Available Spine Technology with FDA Breakthrough Designation
SAN DIEGO--(BUSINESS WIRE)--Carlsmed, Inc. is announcing today that the firstaprevopatient specific spinal surgery has been successfully performed. Christopher Ames, M.D., director of spinal tumor and spinal deformity surgery at UC San Francisco Medical Center, assisted by Patrick Maloney, M.D., performed this landmark surgical procedure. “Carlsmed’s aprevofamily of devices represent ...
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Understanding Induced Pluripotent Stem Cell Differentiation and the Role of iPSC Differentiation Kits in Biological Research
Pluripotent stem cells — cells with the ability to differentiate into nearly any cell type in the body, constituting a significant potential for regenerative medicine. Among these, induced Pluripotent Stem Cells (iPSCs), in particular, have garnered substantial interest from the scientific community due to their ability to be produced from adult cells, eliminating the ethical quandaries ...
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Making the Business Case for Office-Based Hysteroscopy Procedures
For OB/GYN practices looking at the possibility of providing office-based hysteroscopy procedures, the benefits such a move would offer patients is a primary consideration. However, practices must weigh those against multiple economic factors—including capital outlay and reimbursement. To help practices make a more informed decision, this paper provides an overview of the business case for ...
By LUMINELLE
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SPACE BIO-3D PRINTING FROM HUMAN CARTILAGE TO THYROID GLAND IN RODENTS AND TO SPACE ARTIFICIAL MEAT
Space bio-3D printing from Human Cartilage to Thyroid Gland in Rodents and to Space Artificial Meat: SUNKYE Satisfies the Connection and Signal System of Bio-3D Printing in Micro-gravity Environment Space bio-3D printing may be a concept we've heard recently. But as with 3D printing technology, there was only a short accumulation before it happened! Do we need Space bio-3D printing? Can't we ...
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From Predicting Adherence to Health Outcomes – The Power of Predictive Insights
Clinical researchers have begun adopting predictive analytics to anticipate a patient’s engagement in a clinical trial, including if and how a patient will adhere to their treatment plan. As these models are fed more patient-level audio and visual data, they have the potential to open up a whole new world of a patient’s lived experience – from how a patient will respond to their ...
By AiCure
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OneThree`s Workflow for Target and Compound Discovery - Case study
Background OneThree Biotech was born out of the largest precision medicine institute in America with the purpose of decreasing the failure rate of bringing therapeutics to market using biology driven artificial intelligence. Our technology was builtin a lab setting; allowing us to engineer our methodologies around real-world results. While working with major biotech and pharma partners; ...
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CD Genomics Perspective: RNA Sequencing, A Powerful Method for Studying Various Diseases
Although post-mortem brains have been frequently reported as the "gold standard" in transcriptomic research for ND and neuropsychiatric abnormalities, the main sources has been mRNA separated from transgenic animal models and, more lately, patient-derived cell lines. However, despite their promise, transcriptome studies are difficult due to the obvious difficulties in obtaining brain tissue and ...
By CD Genomics
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Carlsmed Raises $30M in Series B Funding to Scale Personalized Spine Surgery
CARLSBAD, Calif.--(BUSINESS WIRE)--Carlsmed announced today that it closed an oversubscribed $30M Series B funding round, led by B Capital Group, a global, multi-stage investment firm. Existing investors, U.S. Venture Partners, The Vertical Group, Cove Fund and Wavemaker Three-Sixty Health, also participated in the round. The company plans to use the Series B funds to ramp commercialization of ...
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Cells isolated from donors with nonalcoholic fatty liver disease exhibit disease phenotypes in 3D bioprinted human liver tissue
Publication Summary: The identification of targets and biomarkers and development of therapeutics for nonalcoholic fatty liver disease (NAFLD) may be accelerated by the use of well-characterized primary cell and tissue reagents, as well as improved in vitro human cell-based disease models, including three-dimensional (3D) bioprinted liver tissue. The characteristics of donors from which the ...
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Ion Channel Screening & Profiling: Unlocking a New Dimension in Drug Discovery
In the realm of drug discovery, researchers are constantly striving to unlock new possibilities for the treatment of diseases. One crucial aspect of this endeavor is the understanding and exploration of ion channels - integral membrane proteins that regulate the flow of ions across cell membranes. These channels play a fundamental role in numerous physiological processes and are essential targets ...
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Navigating Cancer in Collaboration with Experts in Oncology Present Key Research at 2022 ASCO Annual Meeting on Using Digital Health Solutions to Bridge the Health Equity Gap
Navigating Cancer in collaboration with Texas Oncology executes large-scale patient engagement study revealing high digital health solution engagement while demonstrating the opportunity to increase support for diverse patient populations. Scientific and technological advancements have helped enhance cancer care and access to care. Indeed, an important silver lining in the pandemic has been the ...
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Breakthrough Innovations in Bipolar Hip Prosthesis: Improving Mobility and Stability
Hip replacement surgery has been a life-changing procedure for individuals grappling with debilitating hip conditions like osteoarthritis, rheumatoid arthritis, or hip fractures. Over the years, continuous strides in medical technology have ushered in substantial enhancements in hip prostheses, offering patients the prospect of regaining mobility, alleviating pain, and improving their overall ...
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Bridging Clinical Research to Real-World Patient Care Through Predictive Analytics
The ability to predict how a clinical trial participant will adhere to their treatment, and even respond to that treatment, has great promise to advance patient-centric clinical research. But, as we look to understand the impact a drug has on patients’ everyday health outside of a research environment, what happens to these unique, predictive findings around dosing and outcomes once a drug ...
By AiCure
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Understanding the Importance of Preclinical Animal Models in Drug Development
In the world of pharmaceuticals, developing safe and effective drugs is a complex and time-consuming process. Before a new drug candidate can progress to clinical trials and ultimately reach the market, it needs to undergo rigorous testing in various model systems to assess its efficacy and safety. One critical component of this evaluation is the use of preclinical animal models. Preclinical ...
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Early Experience with a Novel Hemodialysis System used for PIRRT Demonstrates Clinical Management at Lower Cost than CRRT and IHD - Case Study
The need for providing dialysis to patients in the ICU has increased overtime. Delivery of this care is challenging to health care systems (HCS) both in costs and ...
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