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Peripheral Neuropathy Articles & Analysis

14 articles found

Unveiling the Intricacies of DNM1L: Function, Associated Diseases, and Inheritance Patterns

Unveiling the Intricacies of DNM1L: Function, Associated Diseases, and Inheritance Patterns

One such disease is Charcot-Marie-Tooth disease type 2A (CMT2A), a hereditary peripheral neuropathy characterized by progressive muscle weakness and sensory loss. CMT2A is caused by mutations in the DNM1L gene, leading to impaired mitochondrial fission and subsequent dysfunction of peripheral nerves. Another disease associated with DNM1L is ...

ByCreative BioMart


Huateng Pharma Develops Intermediates of Carfilzomib For Multiple Myeloma

Huateng Pharma Develops Intermediates of Carfilzomib For Multiple Myeloma

(2) Safety and Tolerability Compared with bortezomib, carfilzomib had less peripheral neuropathy. In RRMM patients, the rate of grade 3 peripheral neuropathy was 1.3%, but no patients had grade 4 events, and only 1% of patients required dose adjustment or Withdrawal. ...

ByHunan Huateng Pharmaceutical Co. Ltd.


Diabetic Foot Ulcer - Case Study

Diabetic Foot Ulcer - Case Study

Subject: 52/male. Insulin dependent diabetic, peripheral neuropathy, hypertension, renal failure on hemodialysis; history of chronic foot ...

ByETS Wound Care


Diabetic Foot Ulcer - Case Study

Diabetic Foot Ulcer - Case Study

Non-insulin dependent diabetes, venous insufficiency, peripheral neuropathy, HTN, CHF, COPD, ...

ByETS Wound Care


Deep Tissue Injury (Traumatic) - Case Study

Deep Tissue Injury (Traumatic) - Case Study

Subject: 68/female. Diabetes, peripheral neuropathy, and venous insufficiency. Necrotic tissue was treated with moistened MIRRAGEN™ advanced wound matrix for 2 days to soften and loosen necrotic tissue for easy ...

ByETS Wound Care


Are Your Hands Going Numb?

Are Your Hands Going Numb?

The following are the 7 most common reasons why your hands might be going numb. There could be a rarer reason (also listed below) for this problem, but you should look into the most common ones first. About Your Numbness In order to better understand what's causing your numb hands it's necessary to consider these 3 questions: Do you have numb hands all of the time or just ...

ByCarpal Pain Solutions. LLC


Treating Peripheral Neuropathy Holistically

Treating Peripheral Neuropathy Holistically

For example, if a patient comes in with a sharp, jabbing pain in his hand - a symptom of peripheral neuropathy - a holistic treatment plan may not only include pain relief medicine but also address underlying causes of pain. ...

ByBioWave Corporation


Treatment of a Pressure Ulcer using CDO Therapy - Case study

Treatment of a Pressure Ulcer using CDO Therapy - Case study

Christine Salcher, DPM Sherman, Texas and Amyee McAlister, Healthline Patient: 50-year-old Caucasian female with a pressure ulcer that has progressively gotten larger, deeper, more malodorous, fibrotic, and necrotic Comorbidities: Diabetes, diabetic retinopathy & peripheral neuropathy Age of Wound: 90 days Days on Service: 55 days Outcome: Goals met. ...

ByEO2 Concepts


Three generations of ADC Nearly a decade of development-PIII   

Three generations of ADC Nearly a decade of development-PIII  

However, Adcetris, when used alone, caused potentially severe peripheral neuropathy, neutropenia, and thrombocytopenia, all of which are typical side effects of antiplatelet drugs. ...

ByCreative Biolabs


Why You Have Numb Fingers While Sleeping

Why You Have Numb Fingers While Sleeping

These reasons are given in order from the most to least common: Sleeping in a bad position Carpal tunnel syndrome Cubital tunnel syndrome Peripheral neuropathy (diabetes and alcohol abuse) Cervical Spondylosis Raynaud's disease Vascular diseases Stroke Multiple sclerosis Medication Side Effects (Chemotherapy) Vitamin B12 Deficiency Numb finger ...

ByCarpal Pain Solutions. LLC


What is a Posturography?

What is a Posturography?

Reid et al. [6] also used posturography to assess the incidence of large-fiber peripheral neuropathy by comparing the results with conventional electromyography (EMG) results. ...

BySensing Future Technologies


Temple research finds that tweaking CBD may help it curb pain and opioid use in mice

Temple research finds that tweaking CBD may help it curb pain and opioid use in mice

Doylestown-based Neuropathix is running safety tests required to start clinical trials in humans. The compound may help with neuropathy, a severe type of chronic pain associated with cancer treatment. ...

ByNeuropathix, Inc.


Philly Pharmacologists are Developing a Promising Pain-Relieving CBD Analog Drug

Philly Pharmacologists are Developing a Promising Pain-Relieving CBD Analog Drug

When tested on mice, their compound, KLS-13019, demonstrated both prevention and reversal of chemotherapy-induced peripheral neuropathy (CIPN), a common side effect of certain cancer treatments that damage peripheral nerves, which carry sensory information to the arms, legs, and brain. ...

ByNeuropathix, Inc.


CBD: Perils, Promise and Development for Neuropathic Pain

CBD: Perils, Promise and Development for Neuropathic Pain

Kannalife is developing proprietary CBD and CBD-like molecules for neurodegenerative disorders, including chemotherapy-induced peripheral neuropathy (CIPN). This is a chronic nerve pain caused by the toxic aspects of chemotherapy drugs. ...

ByNeuropathix, Inc.

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