pharmaceutical development Articles
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Oxygen testing in pharmaceutical research & development - Case Study
As part of their pharmaceutical development, Almac use the Gaspace Advance Micro from Systech Illinois to test oxygen levels in pharmaceutical packaging. The Almac Group was founded by Sir Allen McClay in 2002 with its global headquarters located in Northern Ireland and extensive facilities in the UK, US and Asia Pacific. Almac offer the most comprehensive range of services extending from ...
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Pharmaceutical R&D in an era of managed healthcare: using integrative teams to produce enduring competitive advantage
Medical technology organisations are faced with greater performance pressure in the new managed healthcare environment. In particular, pharmaceutical research and development (R&D) organisations are expected to create new and useful therapeutic treatments with greater resource constraints than ever previously experienced. We explore how pharmaceutical R&D organisations are changing the way they ...
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New trends in biotechnology networking
The paper explores two emerging trends in biotechnology networking: the role of strategic partnering activity in the formation of knowledge-based networked oligopolies particularly in the pharmaceutical industry and the extension of partnering activity in biotechnology from advanced industrial to Third World countries. Both trends, it argues, bear further examination by both researchers seeking ...
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The science of nations: European multinationals and American biotechnology
This paper examines how Europe's large chemical/pharmaceutical multinationals have developed their interests and capabilities in biotechnology and in particular the degree to which, in the process, they have become increasingly linked into the US science base. It looks at both direct linkages via subsidiary laboratories located on US soil and at indirect linkages via the small, dedicated ...
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Sustainable use of biodiversity by the pharmaceutical industry?
This paper discusses a key aspect of a sustainable pharmaceutical use of biodiversity: the increased demand of the pharmaceutical industry for biogenetic resources does not result in an increase of the market value of biodiversity. The increasing interest in biogenetic resources by the pharmaceutical industry since the late 1980s has led, among other things, to contracts between large ...
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Capability portfolio for the initial phase of internationalisation of emerging economy firms: a study in the Indian pharmaceutical industry
This paper analyses the internationalisation experiences of seven firms in the Indian pharmaceutical industry and identifies the portfolio of capabilities required in the initial phase of internationalisation. It traces the priorities, simultaneity and sequence in the capability development process and identifies the differences between early and late internationalisers. It notes that studies so ...
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Challenges to improving access to essential drugs: perspectives from across the divide
This paper examines the principal challenges to improving the accessibility to healthcare and medicines in developing countries. The analysis draws on current literature to provide an overview of the factors that have led to the disparity in healthcare access; the problems of developing nations in overcoming such impediments and the challenges faced by the providers of medicines, namely that of ...
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Bioprospecting: lessons from benefit-sharing experiences
Biodiversity prospecting, or bioprospecting, is the exploration of biodiversity for commercially valuable genetic and biochemical resources. The Convention on Biological Diversity recognises the sovereignty of nations over their bioresources and their rights to share in the benefits that accrue from commercialised bioproducts. Since the Convention was introduced in 1992, many biodiversity ...
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The changing role of technology suppliers in the pharmaceutical industry: the case of drug delivery companies
In this paper, preliminary results of a research project on strategies of drug delivery companies (DDC) are presented to discuss the changing role of technology suppliers in the pharmaceutical industry. Changes in the pharmaceutical industry are presented briefly and related to developments in the drug delivery industry. The early observations are contrasted with existing views from the ...
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Conditions for the achievement of pharmaceutical innovation for sustainable development: lessons from India
This paper shows the post-TRIPS experience to be contradicting the overstated claim that "the adverse effect of TRIPS Agreement on prices of patented medicines would be adequately compensated by the benefits of technology transfer and domestic R&D". It argues that policymakers cannot continue to formulate their strategic interventions with an understanding that "strong IPRs are ...
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Fixing the paradigm for biopharmaceutical R&D: Where to start?
The basic thesis of this paper is that the R&D sector of the new medicines' business is experiencing evolutionary stress. Due to the failure of the regulatory framework and applied sciences to keep pace with advances in discovery, there is a bottleneck in the development phase of R&D. While improved process may help, there are still problems related to the products themselves, such as the need to ...
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Report on International Conference on Healthcare and Food: Challenges of Intellectual Property Rights, Biosafety and Bioethics
Approximately 150 participants attended the conference including representatives from different countries from the developing world, and also from the developed world, who are sensitive to issues for developing countries in the area of interest of the conference Participants included people from academia (biotechnology research, science and technology policy research), government departments, ...
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Biotechnology finds its way to Hong Kong
Up until the beginning of this decade, biotechnology has virtually been non-existent in Hong Kong. By utilising all the favourable advantages available, a new era with emphasis on biotechnology was initiated. Vigorous promotion from the universities coupled with a positive response from the government has finally enabled biotechnology to find its way to Hong Kong. Currently, the local ...
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Opportunities and threats for biological screening of medicinal plants: Importance for the pharmaceutical industries in developing countries
Importance of medicinal plants has been continually increasing both for pharmaceutical industry and traditional users. This review outlines opportunities and threats for biological screening of medicinal plants, focusing on methods useful for the industry and trends in the pharmacological investigations of natural products. Stages and techniques biological (pharmacological) screening and ...
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The changing autarky pharmaceutical R&D process: causes and consequences of growing R&D collaboration in Japanese firms
This paper analyses the changing R&D process at Japanese pharmaceutical companies, based on a questionnaire survey as well as structured interviews at large Japanese pharmaceutical companies. Japanese pharmaceutical companies have recently engaged in active R&D collaborations with other firms and universities. This paper identifies the factors underlying this trend, finding that all three factors ...
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Stability Analysis: A Meaningful, Impactful and At-the-Forefront Tool for Pharmaceutical Science
In the field of pharmaceutical science, stability analysis plays a crucial role in ensuring the safety and efficacy of pharmaceutical products. It is a complex and multifaceted process that requires thorough investigation and understanding of various influencing factors. Stability analysis consists of different methods such as influencing factors analysis, long-term accelerated shelf-life ...
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Plant-based cures for Vector-borne disease
Herb- and plant-based medicines have been used for as long as 60,000 years, with the first written record dating to 7,000 years ago. While these medicines have survived scientific evaluation with varying success, one in four medications currently used has a plant-based origin. One of the most successful medications treats a vector-borne disease. With all this history, why aren’t we ...
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A Brief Introduction to Non-Functional Excipients
Excipients are the general term for all materials in the prescription except the main active ingredients, such as binders, disintegrants, lubricants, fillers, etc. The choice of excipients for oral solid preparations is affected by factors such as the pharmacological and chemical properties of the raw materials, the preparation process and the price of excipients. There are non-functional ...
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Techniques to Enhance Drug Solubility
Solid preparations for oral administration for children have the advantages of convenient carrying and good stability, but for children, they are prone to dysphagia. The liquid dosage form for oral administration for children not only has benefits like large dispersion and fast absorption, but also can improve the bioavailability of some drugs, which has a greater development prospect and ...
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Liposomes as Drug Delivery Vehicles
Due to the amphiphilic nature of lipids in liposomes, they can serve as candidate vehicles for drug delivery, and liposomes have received more attention than other systems because of their remarkable ability to deliver drugs to their target sites. Advantages of Liposomes as Drug Delivery Vehicles l As drug delivery vehicles, liposomes have low toxicity and immunogenicity, and the high ...
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