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Pharmaceutical Drug Articles & Analysis

30 articles found

PEGylation in Pharmaceutical Development: Enhancing Drug Efficacy and Safety

PEGylation in Pharmaceutical Development: Enhancing Drug Efficacy and Safety

Introduction PEGylation, the process of attaching polyethylene glycol (PEG) chains to therapeutic molecules, has become a cornerstone in pharmaceutical development. This technique improves the pharmacokinetic and pharmacodynamic properties of drugs, enhancing their stability, solubility, and circulation time while reducing immunogenicity. ...

ByBOC Sciences


The Role of PEG Derivatives in Advanced Drug Delivery Systems

The Role of PEG Derivatives in Advanced Drug Delivery Systems

Polyethylene glycol (PEG) derivatives have become pivotal in the pharmaceutical industry, revolutionizing drug delivery systems and enhancing the efficacy of various therapeutic agents. The unique properties of PEG derivatives, including their biocompatibility and ability to modify the solubility, stability, and bioavailability of drugs, make ...

ByBOC Sciences


Advanced Methods for Natural Product Extraction

Advanced Methods for Natural Product Extraction

Supercritical fluid extraction is commonly used in the pharmaceutical and food industries due to its high efficiency and selectivity. ...

ByBOC Sciences


Anesthetic Analgesia APIs, Anti-Acid APIs, Anti-anemia APIs, and Anti-Angina APIs

Anesthetic Analgesia APIs, Anti-Acid APIs, Anti-anemia APIs, and Anti-Angina APIs

Active pharmaceutical ingredients (APIs) are biologically active components in pharmaceutical drugs, responsible for the intended therapeutic effects. ...

ByProtheragen-ING


Host Cell Protein Risks and Testing Requirements

Host Cell Protein Risks and Testing Requirements

Risks of HCPs In general, HCP constitutes the major process-related impurity in the drug product in addition to the target protein. The main risk associated with HCP is immunogenicity and they have the potential to affect the safety and efficacy of a given drug product. ...

ByCreative Proteomics


Stability Analysis: A Meaningful, Impactful and At-the-Forefront Tool for Pharmaceutical Science

Stability Analysis: A Meaningful, Impactful and At-the-Forefront Tool for Pharmaceutical Science

Pharmaceutical Analysis Pharmaceutical analysis is a branch of analytical chemistry that deals with the analysis of pharmaceutical substances, including drugs, their formulations, and their compatibility with various excipients. ...

ByCD Formulation


Advances in Molecular Docking Software: Streamlining Drug Discovery

Advances in Molecular Docking Software: Streamlining Drug Discovery

Molecular docking, a critical component of structure-based virtual screening, plays a pivotal role in the field of drug design by predicting the binding interactions between small molecules and proteins. ...

ByCD ComputaBio


ADC Cleavable Linker : Classification and Mechanism of Action

ADC Cleavable Linker : Classification and Mechanism of Action

Antibody-drug conjugates (ADCs), as emerging anticancer drugs, can deliver highly cytotoxic molecules directly to cancer cells to kill them. ...

ByBOC Sciences


Choosing a CDMO: 7 Key Factors to Keep in Mind

Choosing a CDMO: 7 Key Factors to Keep in Mind

The pharmaceutical industry is a highly dynamic industry. It is constantly innovating new and complex drugs with great efficacy. ...

ByNeunco Pharmaceutical


TPD Show Potential For The Treatment of Alzheimer's Disease

TPD Show Potential For The Treatment of Alzheimer's Disease

TPD drugs are one of the hot spots of new drug development in recent years, especially in the field of oncology. For example, a TPD drug developed by Arvinas has achieved proof-of-concept in clinical trials for the treatment of breast and prostate cancer. ...

ByHunan Huateng Pharmaceutical Co. Ltd.


Adaptive Designs in nQuery - Case Study

Adaptive Designs in nQuery - Case Study

Effective and Efficient Drug Development Challenge Increased Cost, Risk, and Competition in the Drug Development Processes Dr. ...

ByStatsol


Recursion Pharmaceuticals Puts Strength on Full Display

Recursion Pharmaceuticals Puts Strength on Full Display

Mapping Biology to Discover New Drugs Recursion Pharmaceuticals is a technology-enabled drug developer. ...

ByRecursion


CanaQuest Medical Corp (OTC: CANQF)

CanaQuest Medical Corp (OTC: CANQF)

About: CanaQuest Medical is an award-winning, Clinical Stage/Life-Sciences company focused on the drug discovery and development of next-generation targeted therapeutics within the endocannabinoid system and specific brain receptors. The Company is focused on treating neurological conditions, such as epilepsy, anxiety, depression, and Post Traumatic Stress Disorder “PTSD,” including ...

ByCanaQuest Medical Corp.


How to Select Pharmaceutical Excipients?

How to Select Pharmaceutical Excipients?

Pharmaceutical excipients refer to the substances used in the production and formulation of medicines. They perform multiple functions in pharmaceutical preparations and are likely to affect the quality, safety and effectiveness of drugs. ...

ByCD Formulation


ABILITY Diabetes Global enrolls thousandth patient: A Cardinal Milestone Achieved

ABILITY Diabetes Global enrolls thousandth patient: A Cardinal Milestone Achieved

About Concept Medical Inc (CMI): CMI is headquartered in Tampa, Florida and has operational offices in The Netherlands, Singapore and Brazil and manufacturing units in India. CMI specializes in developing drug-delivery systems and has unique and patented technology platforms that can be deployed to deliver any drug / pharmaceutical agent across ...

ByConcept Medical Inc.


The Effects of Excipients on Pharmaceutical Preparations in Drug Design

The Effects of Excipients on Pharmaceutical Preparations in Drug Design

This type of pharmaceutical preparations have a common feature, that is, after oral absorption, the drug will enter the body's circulation. By using specific pharmaceutical technology, dextran and certain drugs can be combined through dextran covalent bonding, which have stronger lymphatic circulation tropism than those made with ...

ByCD Formulation


The Effects of Excipients on Pharmaceutical Preparation

The Effects of Excipients on Pharmaceutical Preparation

This type of pharmaceutical preparations have a common feature, that is, after oral absorption, the drug will enter the body's circulation. By using specific pharmaceutical technology, dextran and certain drugs can be combined through dextran covalent bonding, which have stronger lymphatic circulation tropism than those made with ...

ByCD Formulation


Increasing the Efficiency of Drug Development with Preclinical Testing Using Human Intestinal Stem Cells

Increasing the Efficiency of Drug Development with Preclinical Testing Using Human Intestinal Stem Cells

Clearly, fewer liabilities carried into the clinic will result in higher-quality drugs that reach the market more quickly. An Efficient Human Cell–Based Option RepliGut® tissue constructs from Altis Biosystems have the potential to address this critical need in pharmaceutical drug development. ...

ByAltis Biosystems


What’s a life-saving drug worth? It depends…

What’s a life-saving drug worth? It depends…

The risk? According to Medicinenet.com, only 5 in 5,000 drugs that enter preclinical testing advance to human trials. And only 1 of these 5 drugs ultimately gets approved for sale, which means the chance for a new drug to make it to market is 1 in 5,000. That’s a lot of R&D ...

ByVistex Inc


World Health Organization Guidance on the Storage and Transport of Temperature Sensitive Pharmaceutical Products

World Health Organization Guidance on the Storage and Transport of Temperature Sensitive Pharmaceutical Products

Background The World Health Organization (WHO) publish guidelines for the storage and transport of temperature sensitive pharmaceutical products. Many pharmaceuticals, drugs and vaccines have time and/or temperature dependent requirements. ...

ByAKCP

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