Pharmaceutical Formulation Development Articles & Analysis
48 articles found
In the ever-evolving field of biopharmaceuticals, the production of antibodies has taken center stage due to their critical role in therapeutic applications. Among the various production systems available, Chinese Hamster Ovary (CHO) cells have emerged as a gold standard for monoclonal antibody production, and specialized services have been developed to streamline this process. The Significance ...
Introduction PEGylation, the process of attaching polyethylene glycol (PEG) chains to therapeutic molecules, has become a cornerstone in pharmaceutical development. This technique improves the pharmacokinetic and pharmacodynamic properties of drugs, enhancing their stability, solubility, and circulation time while reducing immunogenicity. Since its first FDA-approved application in 1990 with ...
These crucial compounds undergo rigorous research, development, and manufacturing processes before being integrated into final pharmaceutical formulations. ...
Understanding the metabolic stability of potential drug candidates is paramount in the realm of pharmaceutical development. S9 metabolic stability assays provide critical insights into how a compound behaves within biological systems, especially concerning its metabolism, stability, and overall pharmacokinetics. At the core of S9 metabolic stability is the S9 fraction, which is a liver extract ...
These films offer unique advantages in terms of dosage accuracy and controlled release, which are critical in pharmaceutical development. At the forefront of this innovation is CD Formulation, a company that caters to pharmaceutical research entities looking to develop advanced oral drug delivery systems. ...
In the realm of pharmaceutical research and development, ADME testing services play a pivotal role in evaluating the pharmacokinetics of drug candidates. ...
In the rapidly evolving field of pharmaceuticals, nanotechnology has emerged as a revolutionary force, transforming the landscape of drug delivery and formulation development. ...
In vitro permeability assay kits play a crucial role in the field of pharmaceutical development, particularly when evaluating the absorption characteristics of drugs. ...
In the rapidly evolving world of biotechnology, synthetic peptides have emerged as a pivotal component with wide-ranging applications in medical research, diagnostics, and therapeutic developments. These lab-created sequences of amino acids mimic naturally occurring peptides and are instrumental in advancing scientific discoveries and pharmaceutical innovations. This article delves into the ...
CD Formulation’s Role in Oral Liquid Formulation Development Organizations like CD Formulation specialize in providing customized research and development services aimed at addressing such complex formulation challenges. ...
Host cell proteins (HCPs) are protein impurities produced by genetically engineered strains or cell lines. Some of these proteins are necessary for the survival, reproduction and other normal physiological activities of engineered strains or cell lines. HCPs are purified together with the target product during the production process and cannot be removed. Risks of HCPs In general, HCP ...
Ongoing research and inventions in the field of oncology focus on the development of small molecule drug therapies for use in brain tumor resection. Small molecule drugs are being developed to target and effectively treat brain tumors to improve therapeutic outcomes. Small particles containing compounds that can enter cells and interact with specific targets to inhibit or modulate their ...
Trillions of microorganisms live in the gastrointestinal tract, far outnumbering the body's own cells. The intestinal flora is involved in many physiological and pathological processes in the host, including digestion and absorption of food, metabolism of certain nutrients and pharmaceutical compounds, development of host immunity, intestinal inflammatory states, and more. Dysbiosis of the ...
Huateng Pharma, a leading Contract Development and Manufacturing Organization (CDMO), is proud to announce the launch of its latest product, Piroctone Olamine (CAS: 68890-66-4). ...
Pharmaceutical Analysis Pharmaceutical analysis is a branch of analytical chemistry that deals with the analysis of pharmaceutical substances, including drugs, their formulations, and their compatibility with various excipients. ...
Microspheres play a crucial role in the field of pharmaceuticals, biotechnology, and materials science due to their unique properties and applications. These spherical particles, ranging from a few micrometers to several millimeters in size, have a wide range of uses, including drug delivery systems, cell encapsulation, and as supports for various chemical reactions. Polymeric microspheres, ...
Introduction α-Galactosidase, a versatile enzyme, is gaining recognition for its pivotal role in various industries. In this article, we will delve deeper into the scientific underpinnings, applications, and benefits of α-Galactosidase. Our goal is to provide a detailed, informative exploration of this enzyme, grounded in scientific objectivity. α-Galactosidase: An Enzyme at ...
Patient-centric drug development is a divisive concept. Dismissed as a buzzword by some. Adopted extensively by others. ...
In the world of pharmaceuticals, developing safe and effective drugs is a complex and time-consuming process. ...
Carfilzomib, a proteasome inhibitor, is indicated for the treatment of patients with multiple myeloma. Multiple myeloma (multiple myeloma, MM) is a malignant tumor originating from the B cell lineage, characterized by the clonal proliferation of malignant plasma cells in the bone marrow microenvironment, causing fractures and bone marrow failure, and is the second most common blood system ...