pharmaceutical research Articles
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Pharmaceutical R&D in an era of managed healthcare: using integrative teams to produce enduring competitive advantage
Medical technology organisations are faced with greater performance pressure in the new managed healthcare environment. In particular, pharmaceutical research and development (R&D) organisations are expected to create new and useful therapeutic treatments with greater resource constraints than ever previously experienced. We explore how pharmaceutical R&D organisations are changing the way they ...
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Towards a fourth generation R&D management model-research networks in knowledge management
Research and development (R&D) management is increasingly about managing knowledge rather than simply managing its generation. Better management of knowledge is a key success factor for industry competitiveness through continuous innovation. R&D management processes developed in the past, which can be described as the first, second, or third generation models, deal with concepts, techniques and ...
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Oxygen testing in pharmaceutical research & development - Case Study
As part of their pharmaceutical development, Almac use the Gaspace Advance Micro from Systech Illinois to test oxygen levels in pharmaceutical packaging. The Almac Group was founded by Sir Allen McClay in 2002 with its global headquarters located in Northern Ireland and extensive facilities in the UK, US and Asia Pacific. Almac offer the most comprehensive range of services extending from ...
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Challenges to improving access to essential drugs: perspectives from across the divide
This paper examines the principal challenges to improving the accessibility to healthcare and medicines in developing countries. The analysis draws on current literature to provide an overview of the factors that have led to the disparity in healthcare access; the problems of developing nations in overcoming such impediments and the challenges faced by the providers of medicines, namely that of ...
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The particle counter useful for formulation and process developement of parenterals
Comments by major pharmaceutical company research scientist. We've found the Spectrex to be a very useful tool in formulation and process development for parenteral products in cases where the volume of solution available is limited, and we are primarily interested either in 1) differences in relative numbers and sizes of particles when comparing various formulations or processing treatments, or ...
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Purdue University Workshop on Pharmaceutical Lyophilization
Get up close and personal with a Computrac Vapor Pro XL at the 2018 LyoHUB/ASTM E55 Workshop on Pharmaceutical Manufacturing Research. For full information and registration info, visit www.astm.org/E55WorkshopOct2018. You must register by 10/10/18 to attend. About the Event The Workshop on Pharmaceutical Lyophilization will be held Tuesday, October 23, 2018. Sponsored by ASTM Committee E55 on ...
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How benchmarking can lever cluster competitiveness
New international trade theory postulates intra-industry trade as a major component. Regarding research as a traded item, this is complex as it can be both intra- and inter-industry trade, a problem for future industry classifications. However, research trade from university centres of excellence and research institutes is now a major feature of territorial competition. The example of this to be ...
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R&D and knowledge dynamics in university–industry relationships in biotech and pharmaceuticals: an agent–based model
In the last two decades, university–industry relationships have played an outstanding role in shaping innovation activities in biotechnology and pharmaceuticals. Nevertheless, there still is an intensive and open debate concerning their short and long term effects on the research system in life sciences. This work introduces a new way to analyse university–industry relationships ...
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Biotechnology clusters, "Big Pharma" and the knowledge-driven economy
The pharmaceutical industry remains powerful due to its firm scale and global reach. However, analysis of the source of biotechnology-derived products in healthcare, valued at $70 billion worldwide by 2000, reveals an almost complete dependence, in three key markets of the USA, UK and Germany, on products developed by entrepreneurial biotechnology firms. These tend to operate in knowledge-driven ...
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Breaking Down Barriers: How Enzymes are Revolutionizing Research and Diagnostics
Enzymes play important roles in research and diagnostic applications. Enzymes are natural biological catalysts that accelerate the rate of biochemical reactions, and they are widely used in many different fields. In this article, we have discussed the applications of enzymes in research and diagnostics, as well as some of the most common enzymes used. Enzymes have a wide range of applications ...
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What Are the Methods for Preparing Microspheres?
Microspheres play a crucial role in the field of pharmaceuticals, biotechnology, and materials science due to their unique properties and applications. These spherical particles, ranging from a few micrometers to several millimeters in size, have a wide range of uses, including drug delivery systems, cell encapsulation, and as supports for various chemical reactions. Polymeric microspheres, ...
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In Silico Sorcery: Envisioning Tomorrow's Drugs Today with Computational Design
In the dynamic realm of drug discovery, the pursuit of innovative and effective treatments for diverse diseases demands groundbreaking approaches that can expedite the drug development lifecycle. Amidst these endeavors, Computer-Aided Drug Design (CADD) has emerged as a transformative methodology, harnessing the power of computational tools and simulations to predict, understand, and optimize the ...
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Network meta-analysis: for solving an elephant`s problem
Medical progress happens every day with new medicines, devices, and diagnostic tools steadily emerging. How can patients fully benefit from these? How can doctors and pharmacists stay up to date with the endless stream of pharmaceutical research? How can you make medical decisions when comparisons between all medicines are rarely available? Well, a network meta-analysis (NMA) might be the ...
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Spray Drying of polymeric micelles - Case Study
Customer: Technion-Israel Institute of Technology, Haifa, Israel The research focuses on the pharmaceutical nanomaterials science and drug delivery fields, with special interest in biomaterials science, colloidal chemistry (drug and polymer self-assembly), mucoadhesive drug delivery systems, nanomedicine (drug encapsulation, release and targeting). Application: Drying polymeric micelles ...
By BUCHI
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How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study
Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...
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How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study
Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...
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A Healthy Environment - In life sciences and pharmaceuticals, it’s the key to success
With 1,000 miles of airways, 60,000 miles of blood vessels, and 100 trillion cells1, the human body is often referred to as the world’s most complex machine. So it’s no surprise that industries such as pharmaceuticals and life sciences, devoted to keeping that machine in good working order, require a complex and highly exacting set of operating environments. Manufacturers in these ...
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The Key Factor of Excellent Drug Efficacy: Chemical Structure of Drug
How to keep the drug active and give full play to its therapeutic effect has always been the primary problem to be solved by researchers in the field of pharmacy. It is a very complex process from drug administration to the generation of drug efficacy. Scientists have divided this process into three phases: Pharmaceutical phase, pharmacokinetic phase and pharmacodynamic phase. Only by ensuring ...
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International scientists' priorities for research on pharmaceuticals and personal care products in the environment
Pharmaceuticals and personal care products (PPCPs) are widely discharged into the environment via diverse pathways. The effects of PPCPs in the environment have potentially important human and ecosystem health implications, so credible, salient, and legitimate scientific evidence is needed to inform regulatory and policy responses that address potential risks. A recent 'big questions' exercise ...
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Cryopreservation Process, Methods and Storage Solution Explored
The Cryopreservation Process The Cryopreservation Process is where biological matter (cells, tissue, organs, etc) is preserved by cooling to a very low temperature. This process stops the normal cell functions and holds the sample in suspended animation. When the time comes to thaw the sample, normal biological function resumes.Cryopreservation Process Steps The cryopreservation process can be ...
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