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Pharmaceuticals Articles & Analysis
506 articles found
In toxicology studies, these blocks can help evaluate the immunotoxic effects of various substances, providing critical data on the safety and efficacy of pharmaceuticals and environmental chemicals. Moreover, due to the anatomical and physiological similarities between rats and humans, findings from rat studies often hold relevance for human health. ...
Many oncology drugs have been abandoned by pharmaceutical companies due to poor performance in phase I, II, or III clinical trials. ...
It allows them to: Diagnose and Monitor Disease: Quantifying specific sterols can serve as biomarkers for various metabolic disorders. Advance Pharmaceutical Research: Understanding how a drug interacts with sterol pathways is crucial for developing new therapies, from cholesterol-lowering statins to novel antifungal agents. ...
Abstract In pharmaceutical synthesis, heavy metal catalysts are commonly used, and their residues often remain in the final product. ...
Researchers can generate and test numerous lipid variants simultaneously, facilitating the discovery of novel lipid-based compounds with potential pharmaceutical applications. 5. Microfluidic Synthesis Emerging technologies in lipid synthesis include microfluidic systems, which enable the precise control of reaction conditions at a microscale. ...
In the pharmaceutical industry, excipients play a crucial role in the formulation of medicines. ...
While often associated with aerospace, semiconductor, and chemical industries, fluoropolymers also play a vital—yet underappreciated—role in pharmaceutical manufacturing, particularly in producing allergy ...
Among various expression systems, Chinese Hamster Ovary (CHO) cells have emerged as the preferred choice for many researchers and pharmaceutical companies. This article delves into the significance of recombinant protein expression services specifically utilizing CHO cells, exploring the advantages, methodologies, and applications. ...
Tailored Antibody Production The CHO cell antibody drug production service offers a comprehensive solution for researchers and pharmaceutical companies looking to develop and manufacture monoclonal antibodies. ...
Introduction PEGylation, the process of attaching polyethylene glycol (PEG) chains to therapeutic molecules, has become a cornerstone in pharmaceutical development. This technique improves the pharmacokinetic and pharmacodynamic properties of drugs, enhancing their stability, solubility, and circulation time while reducing immunogenicity. ...
Similarly, transaminases and dehydrogenases are increasingly poised as key tools in chiral intermediate synthesis for pharmaceutical manufacturing, enabling enantioselectivity that surpasses classic chemical methods. ...
The increasing application of Lactobacillus species in biotechnology, pharmaceutical sciences, and clinical research has necessitated a more nuanced understanding of strain-specific characteristics and formulation parameters. ...
Active Pharmaceutical Ingredients (APIs) form the foundation of modern pharmaceuticals, serving as the biologically active components responsible for the therapeutic effects of medications. These crucial compounds undergo rigorous research, development, and manufacturing processes before being integrated into final pharmaceutical formulations. ...
Every development stage of the services undergoes strict evaluations that ensure top-level safety and effectiveness, building confidence between the pharmaceutical company and customers. Alfa Cytology works to establish cooperative relationships between academic institutions and research organizations. ...
As the field of drug development advances, the continuous refinement of this assay will be essential in meeting the growing demand for effective and safe pharmaceuticals. ...
As spring arrives, so does a renewed focus on cleaning, quality, and process validation in pharmaceutical facilities. Whether it’s a routine seasonal turnover or preparation for ramped-up production cycles, spring is a critical time in the pharmaceutical industry for equipment maintenance, cleaning validation, and ensuring product purity. Behind every ...
As spring arrives, so does a renewed focus on cleaning, quality, and process validation in pharmaceutical facilities. Whether it’s a routine seasonal turnover or preparation for ramped-up production cycles, spring is a critical time in the pharmaceutical industry for equipment maintenance, cleaning validation, and ensuring product purity. Behind every ...
This provides an innate channel and repository for transporting pharmaceuticals. Platelets naturally function as superior drug carriers because of the unique receptors on their surface. ...
Nitrogen compounds are a crucial aspect of pharmaceutical chemistry, particularly in the development of antibiotics. ...
Understanding the metabolic stability of potential drug candidates is paramount in the realm of pharmaceutical development. S9 metabolic stability assays provide critical insights into how a compound behaves within biological systems, especially concerning its metabolism, stability, and overall pharmacokinetics. ...