Physiological And Cellular Responses Articles & Analysis
18 articles found
The evaluation of cardiovascular toxicity is a significant challenge in drug development. Preclinical evaluation of cardiovascular safety involves a multifaceted approach, encompassing a plethora of in vitro and in vivo endpoints. These assessments continuously evolve, aiming to mitigate the incidence of cardiovascular toxicity that may emerge during clinical trials. To shed light on the ...
These systems are preeminent in their ability to control gene expression, which is utterly essential for examining the kinetics of cellular processes, signaling pathways, and protein functionality. Experimenting with these cellular mechanisms in stable cell lines offers researchers a dynamic platform for probing into cell behavior. In certain circumstances, ...
Characteristics of Cytokines (1) Multipotency: Cytokines exhibit the ability to interact with different cell types, exerting their effects across a wide spectrum of cellular targets. (2) Overlap: There is often functional similarity or identity between two or more cytokines, leading to analogous biological effects. (3) Synergism: Certain cytokines are capable of ...
In medicine, taking a holistic approach means treating the whole person - body, mind, spirit, and emotions - to achieve one’s optimal health and wellness. For example, if a patient comes in with a sharp, jabbing pain in his hand - a symptom of peripheral neuropathy - a holistic treatment plan may not only include pain relief medicine but also address underlying causes of pain. A holistic ...
With the current in vivo animal models, it is difficult to determine the mechanism of action of physiologic responses that translate to human medicine, as there are too many variables that can confound a researcher’s ability to draw definitive conclusions. ...
The Pearl River estuary, southern China, suffers from multiple sources of metal contamination as a result of the rapid industrial development in the region; but the biological impacts of contamination remain unknown. In the present study, a euryhaline oyster, Crassostrea hongkongensis, was collected from different sites of the Pearl River estuary; and various physiological (heart rate, ...
Changes in tissue transcriptomes and productivity of Arabidopsis thaliana were investigated during exposure of plants to two widely used engineered metal oxide nanoparticles, titanium dioxide (nano‐titanium) and cerium dioxide (nano‐cerium). Microarray analyses confirmed that exposure to either nanoparticle altered the transcriptomes of rosette leaves and roots, with comparatively larger ...
Organs influenced by immune dynamics in the gut.(1) A Gut Check for Tumor Overgrowth Enzymes Work Better in a Cage Are IPS Cells Safe for Therapeutic Use? Factors contributing to autoimmune disease development. (2) The human body is the site of a flagrant yet silent invasion. We host as many foreign organisms in and on us as we have cells that make up our own body. A particular ...
Perception of tastes and odors in water is a major interest for water producers and distributors because off-flavors in tap water are associated with health risk by consumers. However, the taste of water is difficult to describe due to the medium itself which is supposed to have no taste. Classical sensory methodologies are difficult to adapt and only get part of the whole perception. This ...
Disastrous effect of nickel on spinach was discussed by number of authors but the effect of amendments like biochar with nickel on Spinacea oleraceaL. is not still discussed by any author of the world because biochar was used as soil amendments which play a vital role in reducing mobilization and uptake of nickel by spinach plants. As nickel contaminated plants are very harmful for the ...
In this paper, we argue that emotional reactions may guide the design of in–vehicle auditory displays since emotion has strong consequences for behaviour and information processing. A simulator study with 30 participants was conducted in which auditory icons were contrasted to abstract earcon sounds in more or less imminent collision scenarios and 3D sounds were tested against monophonic ...
Knowledge of fruit physico–chemical properties and physiological responses is important for the design and development of appropriate postharvest handling and storage systems to reduce losses and maintain quality. The objective of this study was to investigate the changes in physico–chemical attributes and physiology of 'milk' banana cultivar at three ripening stages (unripe, fully ...
The presence of biologically active substances (BAS) in biosolids may enhance plant stress tolerance and growth, but the underlying mechanisms are not well understood. This greenhouse study investigated the effects of untreated biosolids, containing 2.1 µg indole-3-acetic acid (IAA) g–1, and tryptophan-treated biosolids, containing 15.4 µg IAA g–1, on tall fescue [Lolium arundinaceum (Schreb.) ...
This study was conducted to assess the usefulness of sewage sludge amendment (SSA) at 20 and 40% ratios for lady's finger (Abelmoschus esculentus L. var Varsha uphar) by evaluating the morphological, physiological, biochemical and yield responses. Lipid peroxidation, protein and antioxidant levels increased whereas photosynthetic rate, stomatal conductance and variable fluorescence ratio ...
Ice encasement and impermeable winter protective covers can induce anaerobic conditions on golf greens. We assessed plant survival and biochemical changes of annual bluegrass (Poa annua L.) and creeping bentgrass [Agrostis stoloniferous L. var. palustris (Huds.)] exposed to combinations of O2 and CO2 concentrations at low temperatures (1°C or –2°C). Results indicate that lack of O2 (anoxia) ...
Abstract Background: The objective of the study was to investigate the physiological responses of construction workers labouring in thermally stressful environments in the UAE using Thermal Work Limit (TWL) as a method of environmental risk assessment. Methods: The study was undertaken in May 2006. Aural temperature, fluid intake, and urine specific gravity were recorded and continuous heart ...
Given estimates that 1% of our communities suffer from post-traumatic stress [1], we need to continue to improve management of trauma. There are conflicting findings over the effectiveness of managed interventions [2-5]. Some reasons for equivocal findings may include how trauma events are perceived by those encountering such events [6] or presence of a family history of psychiatric disorders ...
Continuous ozone exposure at 0.3 ppm (v/v) (US-OSHA Threshold Limit Value for short term exposure) inhibited aerial mycelial growth and sporulation on ‘Elegant Lady’ peaches wound inoculated with Monilinia fructicola, Botrytis cinerea, Mucor piriformis, or Penicillium expansum and stored for 4 weeks at 5 °C and 90% relative humidity (RH). Aerial growth and sporulation, however, ...