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Physiological Mechanism Articles & Analysis

7 articles found

Differentially Expressed Proteins

Differentially Expressed Proteins

Observing such differential expression is crucial for understanding cellular physiology and disease mechanisms. For example, some proteins may be upregulated or downregulated in health and disease states, or between normal and treated cells.Detection MethodsThe most commonly used technique is mass spectrometry, particularly liquid chromatography-tandem mass ...

ByMtoZ Biolabs


Physiology and Pathology of Coronary Microcirculation

Physiology and Pathology of Coronary Microcirculation

The heart’s circulatory system and coronary flow regulation are highly adapted to the vital role of the heart in sustaining life and to everyday physiological challenges. Understanding coronary physiology is key for treating patients with ischemic heart disease in general, and patients with acute ST elevation myocardial infarction (STEMI) specifically. ...

ByMiracor Medical SA


Discovery of Pathways that Promote Remyelination

Discovery of Pathways that Promote Remyelination

COPII mediates the transport of membrane proteins and soluble proteins from the endoplasmic reticulum to the Golgi apparatus, and abnormal function of COPII inhibits protein secretion and has effects on cell differentiation and homeostasis, and many studies have shown a link between COPII components and human diseases, such as Sec31 mutations leading to severe neurological syndromes. However, the ...

ByProfacgen


A hybrid modeling approach for assessing mechanistic models of small molecule partitioning in vivo using a machine learning integrated modeling platform

A hybrid modeling approach for assessing mechanistic models of small molecule partitioning in vivo using a machine learning integrated modeling platform

Each of these equations focuses on key assumptions of how compound physicochemical properties and specific physiological parameters interact to present themselves in this organ-specific equilibrium constant. ...

ByVeriSIM Life


LUM-201 Elicits Greater GH Response than Standard GH Secretagogues in Pediatric Growth Hormone Deficiency

LUM-201 Elicits Greater GH Response than Standard GH Secretagogues in Pediatric Growth Hormone Deficiency

The synergistic actions of LUM-201 on the physiological mechanisms regulating GH release explain why GH responses are greater in response to LUM-201 compared to traditional tests used to diagnose ...

ByLumos Pharma


Physiological Injury and Bio-mechanical Injury of Aquatic Plants

Physiological Injury and Bio-mechanical Injury of Aquatic Plants

Physiological Injury of Aquatic Plants 1. Insufficient Light During the growth, due to insufficient light, the photosynthetic intensity of aquatic plants will be reduced, the normal growth and development will also be affected. ...

BySenzeal Aquarium-Kenting Ridge Ltd


Physiological mechanisms underlying heterosis for shade tolerance in maize

Physiological mechanisms underlying heterosis for shade tolerance in maize

Heterosis in maize (Zea mays L.) confers stress tolerance. To better understand the physiological mechanisms underlying the differential response of a maize hybrid (CG60 x MBS1236) and its parental inbred lines to shading stress, studies were conducted in a field hydroponic system in Ontario, Canada, from 2004 to 2006. ...

BySoil Science Society of America (SSSA)

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