Platelet Coagulation Articles & Analysis
1 articles found
Another top-selling covalent drug is clopidogrel, which needs to be activated by P450 oxidase in the liver to produce a sulphur-containing compound that then forms a disulfide bond with a cysteine residue in the P2Y12 receptor to inhibit platelet coagulation. The above-mentioned two drugs are now very widely used and were not originally designed to act in a ...