Platelet Function Articles & Analysis: Older
2 articles found
This is based on the well-established evidence that approximately 30-50% of patients carry loss-of-function mutations for the CYP2C19 enzyme responsible for Clopidogrel bioactivation. ...
Many of the heparin dependent antibodies, including those with the IgG isotype, are asymptomatic, and only a subgroup of antibodies is positive in platelet activation assays. What differentiates pathogenic from asymptomatic antibodies is not fully understood, with the exception that there is some relationship between antibody concentration and occurrence of HIT, and that ...