Preclinical Study Articles & Analysis: This-Year
17 articles found
Abstract Cannabis is used by an estimated 192 million people around the world. Most people use cannabis through the inhalation of cannabis smoke, which contains combustion by-products that can negatively affect lung health. Knowledge of these risks has led to a growing interest in cannabis vaporizers, which heat the dry cannabis flower without burning. Vaporizing cannabis still releases ...
In preclinical respiratory studies, traditional methods like plethysmography often require animal restraint and extensive acclimation, limiting their ability to capture dynamic respiratory changes. ...
The effectiveness of ELANE as an antimicrobial enzyme is supported by in vivo studies showing increased susceptibility to bacterial infections in ELANE-deficient models. ...
The development of recombinant MGP protein has enabled researchers to study the molecular mechanisms of calcification control and evaluate therapeutic interventions in a variety of disease contexts. ...
Tissue cross-reactivity studies play an essential role in the understanding of immune responses, particularly in the context of autoimmunity, transplant rejection, and vaccine development. ...
They allow researchers to: (1) Investigate Endocrine Mechanisms: Advanced analysis techniques help researchers study steroid hormone imbalances associated with various conditions, including cortisol dysregulation, reproductive disorders, and adrenal dysfunction in experimental models. ...
According to active collaboration with scientists and clinical experts, the company promotes innovation and speeds up laboratory discoveries to help preclinical practice. Through strategic partnerships, Alfa Cytology focuses on developing FAP-targeted therapies that provide advanced tools for researchers to revolutionize cancer treatment protocols. ...
Ischaemic heart diseases continue to be a major global health concern and a leading cause of death. To develop more effective treatments, it is essential for researchers to work with animal models that closely replicate human cardiac physiology. In a notable step forward, Pius et al. present a refined, minimally invasive ovine model of ischaemia–reperfusion–infarction which ...
Alfa Cytology has officially released its antibody-drug conjugates(ADCs) development services which demonstrates the dedication to fighting cancer through advanced treatment methods. Alfa Cytology, which stands at the forefront of oncology service provision in New York United States, has announced its sophisticated antibody-drug conjugates(ADCs) development services for cancer. The pioneering ...
Efficacy Evaluation Analysis ServiceThe efficacy evaluation analysis service encompasses a wide range of studies designed to assess the therapeutic effects of RDC drugs in preclinical models. This includes evaluating clinical endpoints, such as tumor size reduction and survival rates in animal studies. 6. Toxicity Study ...
“We are excited to provide researchers with access to advanced technologies and extensive support crucial for their transformative studies.” In summary, Alfa Cytology excels in delivering vital services for cancer immunotherapy and cell therapy research, enabling scientists and researchers to push the boundaries of current knowledge and develop next-generation therapies. ...
Preclinical drug discovery represents a critical phase in the development of new therapeutics. ...
Animal models offer researchers valuable insights that cannot be obtained through in vitro studies alone, bridging the gap between laboratory research and human application. ...
Moreover, the services on ovarian cancer model development allow researchers to utilize state-of-the-art preclinical models that closely mimic human ovarian cancer biology. These models enable the in-depth study of tumor behavior and therapeutic response, facilitating the discovery of novel treatment avenues tailored to individual patient profiles. ...
“We are thrilled to provide researchers with access to advanced technologies and comprehensive services critical for their groundbreaking studies.” In summary, Alfa Cytology excels in delivering essential services for cancer immunotherapy research, enabling scientists and researchers to push the frontiers of existing knowledge and develop next-generation therapies. ...
Leukemia, a malignant disorder of the blood and bone marrow, poses significant challenges to both patients and healthcare providers. Traditional treatments, including chemotherapy and radiation, while effective for some, often come with severe side effects and varied success rates. Enter immunotherapy - a groundbreaking approach that is not only redefining leukemia treatment but also offering ...
The evaluation of cardiovascular toxicity is a significant challenge in drug development. Preclinical evaluation of cardiovascular safety involves a multifaceted approach, encompassing a plethora of in vitro and in vivo endpoints. These assessments continuously evolve, aiming to mitigate the incidence of cardiovascular toxicity that may emerge during clinical trials. To shed light on the ...