radiotherapy treatment Articles
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Advancing Cancer Treatments with ALZET Osmotic Pumps
The research summarized in this whitepaper provides a number of examples of how ALZET® pumps offer a superior pre-clinical drug dosing option for the delivery of a wide array of anti-cancer agents, including small molecules, immunotherapies, radiotherapies, combination treatments, and novel drug entities. This whitepaper also explores how ALZET® pumps have been used to successfully test ...
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Development of an in vivo assay for detection of non-targeted radiation effects
An adaptive response may be defined as the effect of a small priming dose of radiation modifying the anticipated cellular response of the same tissues so as to alter the predicted response to a larger dose of radiation. We and many others have demonstrated that at low radiation doses (less than 0.5 Gy) the lethal and mutational effect of the radiation is mainly, possibly entirely, due to the ...
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Recent developments in therapeutic applications of atomic and nuclear radiations
In recent years, the major 'challenge' of radiation treatment is to deliver large enough doses to the most resistant cancer cells to provide a high probability of local control while minimising the dose to normal tissues and hence reducing complications. With recent developments in 'imaging' the metabolic or functional status of cancers, the position of tumours relative to surrounding normal ...
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Clinical significance of low-dose radiation therapy: radiation hormesis
This study was designed to investigate the clinical significance of low-dose radiation therapy, radiation hormesis, and accuracy of therapeutic regimen. Radiation hormesis was performed in six patients (four patients with malignant diseases and two patients with benign diseases) in the experimental room where they could be exposed to a low level of direct gamma ray and inhale radon gas ...
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GammaTile Surgically Targeted Radiation Therapy (STaRT) Improving Access to Brain Tumor Care without Compromising Outcomes
ABSTRACT Patients with brain tumors face enormous challenges after diagnosis. Many of these challenges are amplified by issues related to access to care.1‒4 Studies suggest that patients with cancer who live farther from radiation treatment centers have poorer clinical outcomes. In addition, minorities are more likely to perceive longer travel distances as a barrier, which may cause them ...
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Science: Knockout of this epigenetic gene gives CAR-T cells the ability to continuously attack cancer cells
Simply put, CAR-T is to transform the patient's immune T cells in vitro by biotechnology, so that they recognize antigens on the surface of tumor cells, and then inject these cells back into the patient to achieve the therapeutic effect of recognizing and killing cancer cells. In 2017, CAR-T therapy was first approved by the FDA for the treatment of blood cancers such as leukemia and lymphoma. ...
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