Recombinant Antibody Articles & Analysis
8 articles found
Recombinant protein drugs are protein-based therapeutic drugs which are produced by using DNA recombination technology or other biotechnological methods. These drugs include cytokines, peptide hormones, recombinant enzymes, monoclonal antibodies, and fusion proteins. Compared to traditional low-molecular-weight synthetic drugs, ...
Both methods can detect the complete molecular weight. Total antibody analysis Total antibody analysis measures all antibodies in the sample, including bound antibodies (DAR≥1) and unbound antibodies (DAR = 0), which can be used to assess whether the ADC meets the general PK characteristics of monoclonal ...
Yeast produces biotinylated recombinant antibodies in vivo. Researchers have now developed a new method to generate in vivo biotinylated recombinant antibodies secreted by yeast. ...
This is fundamental in achieving reliable, cost-effective production of therapeutic proteins such as monoclonal antibodies, vaccines, recombinant proteins and other vital biopharmaceutical products. ...
The construction of bispecific antibodies in the KineTAC class is not complicated by light-heavy chain mismatches, a common problem in traditional bispecific antibodies. ...
Why target GPCRs with antibodies? The G Protein-coupled receptor (GPCR) superfamily represents the largest and single most important family of human drug targets. GPCRs play a central role in a plethora of biological processes and are linked to a wide range of therapeutic areas including cancer, diabetes, inflammation, cardiovascular diseases, and chronic pain. Expressed in every type of cell in ...
Antibody-drug conjugate (ADC) is one of the fastest growing fields in tumor therapy, which consists of monoclonal antibody (Antibody), linker (Linker) and active drug (Payload). ...
Abstract We previously generated 32 rotavirus-specific (RV-specific) recombinant monoclonal antibodies (mAbs) derived from B cells isolated from human intestinal resections. ...