Resistance Drought Resistance Disease Articles & Analysis
17 articles found
In recent years, the rise of drug-resistant cells has emerged as one of the most significant challenges in the field of medicine, particularly in oncology and infectious diseases. The effectiveness of current therapies is often hindered by the ability of certain cell populations to develop resistance, leading to treatment failure and disease progression. This article explores the importance of ...
Applications of genome editing in model plants include enhancing disease resistance, increasing stress tolerance, and optimizing growth characteristics. In Arabidopsis, for instance, scientists have successfully edited genes to confer resistance to various pathogens. In rice, genome editing has enabled the development of strains with improved ...
Understanding Clonality Analysis Clonality refers to the origin of a cell population from a single 'parent' or progenitor cell through asexual reproduction or division. This concept is vital in cancer studies as it helps track the development of tumor cells from a single mutated cell. Clonality analysis is thus essential in understanding the evolution and the spread of cancerous cells in a ...
Introduction RNA Lipid Nanoparticles (LNP) technology has rapidly gained prominence in the health and scientific domain, primarily due to its significant role in carrying the mRNA of the COVID-19 vaccines developed by Pfizer/BioNTech and Moderna. Yet, the potential of this technology spans beyond the confines of these vaccines or even the health industry. As research into premade RNA-LNP products ...
Proteolysis Targeting Chimeras (PROTACs) are a novel approach for degrading target proteins. Recently, a new split-and-mix PROTAC (SM-PROTAC) system based on liposome self-assembly, known as LipoSM-PROTAC, was reported in the Journal of the American Chemical Society. The LipoSM-PROTAC system exhibits selective degradation of target proteins, with folate serving as a key ligand. In this study, the ...
Understanding Clonality Analysis Clonality refers to the origin of a cell population from a single 'parent' or progenitor cell through asexual reproduction or division. This concept is vital in cancer studies as it helps track the development of tumor cells from a single mutated cell. Clonality analysis is thus essential in understanding the evolution and the spread of cancerous cells in a ...
The phenomenal advancements in the realm of biotechnology have propelled the development of tools with remarkable potential, considerably altering the landscape of biological and medical research. One such groundbreaking tool topping the list among modern biotechnologies is the Single Guide RNA (sgRNA) library. This article will delve into the present and future applications of this revolutionary ...
The Challenge: To understand the molecular effect of a ph-3 drug (Drug A) which showed moderate outcomes and to recommend next steps to increase response ...
Long non-coding RNAs (lncRNAs) are a class of RNAs that do not code for proteins and are typically greater than 200 nucleotides in length. Studies have shown that lncRNAs are quite complex in function and play an important role in various biological processes such as development, differentiation, proliferation, metastasis, apoptosis, stem cell pluripotency, and DNA damage. Therefore, those ...
The massive growth of transcriptomics beyond clinical biology and into the fields of ecology and evolution has been fueled by RNA sequencing (RNA-seq). RNA-seq promised unprecedented sensitivity for sensing the expression differences among rare transcripts, splice variants, and microRNAs, then quickly surpassing microarrays as the high-throughput method for studying differential expression in ...
Researchers at the Children's Hospital of Philadelphia (CHOP) have made a breakthrough in the treatment of aggressive solid cancers, and they have developed a new cancer treatment that targets proteins within tumor cells that are essential for tumor growth and survival, but this has not been possible before. Using the power of large data and advanced computational methods, researchers can ...
Details:The Kyminasi Plant Booster (KPB) technology was installed on a field of three coffee cultivars, including Colombia, Caturra, and Castillo, in the country of Colombia. The field had been under cultivation for six years and part of the field was under renovation. The field was managed without any ...
Synonyms Rainbow Trout Fry Syndrome (RTFS) Bacterial fry anemia Low temperature disease Peduncle disease Saddleback Tail-rot Systemic myxobacteriosis Cause of the Disease Bacterial Coldwater Disease (BCWD) is caused by Flavobacterium psychrophilum, also known as Flexibacter psychrophilus and Cytophaga psychrophila. There may be strain differences among isolates but their importance ...
Cassava (Manihot esculenta Crantz) is commonly grown on residual moisture after rice (Oryza sativa L.) in inland valley swamps (IVS), but not much work has been done to select genotypes that could bulk early, and have high storage root yield in the IVS. Earlier improvement work focused on development of varieties adapted to upland conditions (12-mo cycle), but recently farmers are requesting ...
Tan spot (caused by Pyrenophora tritici-repentis) and Stagonospora nodorum blotch (SNB), (caused by Phaeosphaeria nodorum) are destructive diseases of wheat (Triticum aestivum L.). The majority of currently grown wheat varieties are susceptible to both diseases, presumably because of high pathogenic variability occurring in these fungi or narrow genetic background for resistance in wheat ...
One of the major advances serving to define the beginning of the era of modern medicine was the development of penicillin in the early 1940s as the first widely used antibiotic effective against microorganisms (reviewed in reference 111). In what has become an all-too-common trend, antibiotic-resistant isolates emerged soon after the large-scale use of penicillin to treat bacterial infections ...
One of the major advances serving to define the beginning of the era of modern medicine was the development of penicillin in the early 1940s as the first widely used antibiotic effective against microorganisms (reviewed in reference 111). In what has become an all-too-common trend, antibiotic-resistant isolates emerged soon after the large-scale use of penicillin to treat bacterial infections ...