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Rt Pcr Articles & Analysis

37 articles found

Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2

Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2

Cell lysates were prepared as described in the “Preparation of cell lysates and WES™ analysis” section for WES™ analysis. 2.4 Virus titer determination The viral titers of IAV and SARS-CoV-2 viruses were determined using a real-time one-step multiplex RT-qPCR method. Briefly, viral nucleic acid extraction was performed using a QIAamp Viral RNA Mini Kit ...

ByAtriva Therapeutics GmbH


Chimeric RNA and Sequencing Technologies: Advancing Detection and Research

Chimeric RNA and Sequencing Technologies: Advancing Detection and Research

Traditional sequencing methods, like Sanger sequencing and reverse transcription PCR (RT-PCR), have been historically employed for chimeric RNA detection. ...

ByCD Genomics


The Molecular Microbiology of SARS-CoV-2: Detection Methods and Infection Mechanism

The Molecular Microbiology of SARS-CoV-2: Detection Methods and Infection Mechanism

Verified SARS-CoV-2 cases have been recognized as a beneficial result of a high-throughput sequencing or RT-PCR assay for respiratory specimens such as nasal/pharyngeal swab specimens, saliva specimens, bronchoalveolar lavage fluid, or as a positive outcome of IgM/IgG anti-SARS-CoV-2 or titer anti-SARS-CoV-2 IgG antibodies during recovery was four times or higher ...

ByCD Genomics


qPCR for SARS-CoV-2 Detection and Research: Introduction, Principles, and Applications

qPCR for SARS-CoV-2 Detection and Research: Introduction, Principles, and Applications

While RNA is like DNA, it is substantially different to imitate it very ineffectively with Taq polymerase, the conventional enzyme used for DNA amplification. Subsequently, a version of the PCR test called reverse transcription (RT)-PCR, detects RNA. This involves a two-step technique that typically consists of two enzymes; the first step ...

ByCD Genomics


Host Cell Residual DNA: Understanding its Significance and Detection Methods

Host Cell Residual DNA: Understanding its Significance and Detection Methods

Host Cell Residual DNA (rcDNA) refers to fragments of DNA derived from host cells that may be present in biological products. These products must not contain foreign substances, particularly host DNA, to avoid immune rejection and potential threats to life safety. Regulatory agencies worldwide have imposed strict limits on the amount of rcDNA, and various pharmacopoeias have outlined several ...

ByCreative Proteomics


COVID-19 Disease Testing; Utilising Fluorescence During a Pandemic

COVID-19 Disease Testing; Utilising Fluorescence During a Pandemic

To this end, several diagnostic methods have been designed and tested, and one USA FDA approved test kit utilises fluorescence based reverse transcript real-time polymerase chain reaction (rRT-PCR) technique. The rRT-PCR test works by detecting replicated nucleic acid copies from the SARS-CoV-2 virus through a bound fluorescence probe that is released from its ...

ByEdinburgh Instruments - TECHCOMP Group


The Benefits of Lyophilized Reagents and Assay Kits (and Monkeypox Virus RT-PCR Kit)

The Benefits of Lyophilized Reagents and Assay Kits (and Monkeypox Virus RT-PCR Kit)

Note: The kit is available for diagnostic use in all countries that accept the EU CE-IVD Mark. This MPV RT-PCR Kit is still available for research use in the U.S. and other countries. ...

ByFireGene


Under Sewer-Veillance - Wastewater & COVID-19

Under Sewer-Veillance - Wastewater & COVID-19

Wastewater & COVID-19 Connections When the word wastewater crosses your mind, there is probably also a memory of your Mom’s voice telling you – wash your hands! When humans transitioned into community living, keeping your living space separate from your bathroom space was an important rule to learn. We can thank early scientists who were curious about how diseases spread and ...

ByFlottweg SE


Choosing a Real-Time PCR Cycler that works for Your Lab

Choosing a Real-Time PCR Cycler that works for Your Lab

A real-time PCR cycler can be a significant investment for a lab, and if you’re responsible for the purchase decision you’ll want to do your due diligence and make a future-proof choice. So where do you begin your search? ...

ByBio Molecular Systems


SARS-CoV-2 Multi-FAST

SARS-CoV-2 Multi-FAST

We have great news to share: we launched Schep SARS-CoV-2 Multi-FAST, a new PCR diagnostic test for the rapid detection of SARS-CoV-2, now in multiplex and in a single step format! Simple detection, by reverse transcription and Real Time PCR. It consists of a single Master Mix, ready to use, containing the enzymes, primers and probes, specific for 3 viral genes: Envelope (E), Nucleocapsid (N) ...

ByBiocientífica S.A.


Biocientifica SA develops a new high sensitivity RT-PCR kit for SARS-CoV-2

Biocientifica SA develops a new high sensitivity RT-PCR kit for SARS-CoV-2

The Argentinian National Administration of Drugs, Food and Medical Technology (ANMAT) approved New kitfor the qualitative detection of the SARS-CoV-2 virus based on Real-Time RT-PCR technology. The Argentinian National Administration of Drugs, Food and Medical Technology (ANMAT) approved Schep SARS-CoV-2 RT-PCR Duo Biocientfica ...

ByBiocientífica S.A.


Same-Day COVID Testing for Travelers

Same-Day COVID Testing for Travelers

IGeneX COVID-19 Airline Travel Program IGeneX offers two different expedited COVID-19 RT-PCR tests for travelers or anyone with time-sensitive testing needs. ...

ByIGeneX


hspCas9-RT-PCR Primer Set

hspCas9-RT-PCR Primer Set

Overview Confirm Cas9 mRNA expression With our ready-to-use Cas9 RT-PCR primer set, you can quickly and easily confirm Cas9 expression in cells or in vitro transcription assays. ...

ByGBI - Genera Biosystems Ltd.


Why Speed is of the Essence for Airport COVID-19 PCR Testing

Why Speed is of the Essence for Airport COVID-19 PCR Testing

As the world opens up over the coming months and years, there will be countless plane journeys to see loved ones, meet new family members and travel for work and leisure. Many of these travellers will first need to provide evidence of a negative PCR test to show they pose a minimal COVID-19 transmission risk. Time is proving of the essence for testing. With reports of multi-hour queues at ...

ByBio Molecular Systems


Fluxergy Expands to Scale Up COVID-19 Test Production and Prepare for Testing Beyond COVID-19

Fluxergy Expands to Scale Up COVID-19 Test Production and Prepare for Testing Beyond COVID-19

Fluxergy, a company that has already made headlines for earning a CE mark for its one-hour COVID-19 RT-PCR test, has expanded its U.S. headquarters after commercializing the test globally. ...

ByFluxergy


The Impacts of COVID-19 on Scientific Research - and What to Expect Moving Forward

The Impacts of COVID-19 on Scientific Research - and What to Expect Moving Forward

While some had their research grind to a halt, others have pivoted or have been redirected to support the new global cause – everything from conducting RT-PCR sampling and testing, to SARS-CoV-2 research. There have been both winners and losers as a result. ...

ByBio Molecular Systems


Mic and Myra Prove Flexible and Reliable in Regional Mobile Labs

Mic and Myra Prove Flexible and Reliable in Regional Mobile Labs

The choice was made to field test a Mic magnetic induction thermal cycler and Myra liquid handling robot from Bio Molecular Systems, using a duplex RT-PCR assay from Co-Diagnostics. ...

ByBio Molecular Systems


SARS-CoV-2 (Coronavirus) Detection in Wastewater

SARS-CoV-2 (Coronavirus) Detection in Wastewater

SARS-CoV-2 detection workflow in wastewater Monitoring wastewater for SARS-CoV-2 – or Coronavirus as it is more commonly known – can be a valuable data resource for an effective COVID-19 management. However, there are several challenges involved in detecting biological parameters in wastewater. Fortunately, there are also several solutions available to overcome them. Wastewater ...

ByAnalytik Jena - an EndressHauser Company


SARS-CoV-2 (Coronavirus) Detection Workflow for Research Use Only

SARS-CoV-2 (Coronavirus) Detection Workflow for Research Use Only

Overview of the SARS-CoV-2 (Coronavirus) Detection Process In December 2019 the novel SARS-CoV-2 (formerly named 2019-nCoV) was identified in Wuhan, the capital of China’s province Hubei. Based on its rapid spreading with more than 105,000,000 confirmed cases by beginning of February 2021 the World Health Organization declared the outbreak a public health emergency of international ...

ByAnalytik Jena - an EndressHauser Company


Multiplex real-time PCR: A guide to application

Multiplex real-time PCR: A guide to application

Multiplex real-time PCR: A guide to application In multiplex real-time PCR (qPCR), scientists amplify two or more target genes in the same reaction, using the same reagent mix. Multiplexing allows scientists to overcome limitations for myriad applications. First and foremost, multiplexing enables scientists to conserve valuable samples used in a quantitative assay, which is especially ...

ByAnalytik Jena - an EndressHauser Company

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