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Sample Preparation Articles & Analysis

31 articles found

Application of R3/R5 Microwave Digestion Systems in the Elemental Analysis of Active Pharmaceutical Ingredients (APIs)

Application of R3/R5 Microwave Digestion Systems in the Elemental Analysis of Active Pharmaceutical Ingredients (APIs)

This application demonstrates the use of the R3/R5 microwave digestion systems to prepare samples of carbamazepine, an active pharmaceutical ingredient (API), for trace metal analysis. ...

ByTianezk Instrument Manufacturing (Chengdu) Co., Ltd.


Comprehensive Guide to Glucosinolates: Plant Defense, Human Health, and Cutting-Edge Analytical Methods   

Comprehensive Guide to Glucosinolates: Plant Defense, Human Health, and Cutting-Edge Analytical Methods  

The bioavailability and activity of glucosinolates in humans depend on factors such as food preparation methods, gut microbiota composition, and individual metabolic responses. ...

ByCreative Proteomics


Exploring How RNC-RNA Sequencing Illuminates Translational Dynamics and Molecular Mechanisms   

Exploring How RNC-RNA Sequencing Illuminates Translational Dynamics and Molecular Mechanisms  

The study of gene TR changes in different samples is important for understanding the molecular mechanism of ncRNAs. ...

ByCD Genomics


T Cell Antigen Receptor Sequencing

T Cell Antigen Receptor Sequencing

This technology identifies the diversity and specificity of T cells by measuring the sequences of the rearrangement regions of the TCRβ chain or α chain genes.(1) Sample Preparation: Total RNA or DNA is extracted from blood, tissue, or other samples enriched with immune cells.(2) Amplification: PCR amplification is performed using specific ...

ByMtoZ Biolabs


Determination of Collagen Protein Content in Liquid Phase

Determination of Collagen Protein Content in Liquid Phase

These techniques can separate, identify, and quantify collagen and its hydrolysis products in the samples.Common methods for collagen content determination include:1. Sample PreparationCollagen is extracted from the sample and preprocessed by centrifugation, filtration, or using Solid Phase Extraction (SPE) to remove impurities and purify the collagen.2. ...

ByMtoZ Biolabs


Metabolomics Technologies in Medical Research

Metabolomics Technologies in Medical Research

Metabolomics Research Methods Metabolomics collects samples through established metabolomics research methods, and subsequently uses techniques to obtain metabolites, determine whether there are statistical differences in metabolites between groups and perform further analysis. ...

ByCreative Proteomics


Bile Acid: A Comprehensive Exploration of Function and Metabolism

Bile Acid: A Comprehensive Exploration of Function and Metabolism

This dynamic duo offers unparalleled insights into bile acid composition, concentration, and structural diversity. In LC-MS, bile acid samples are first separated based on their physicochemical properties, such as polarity and size, using liquid chromatography. ...

ByCreative Proteomics


Cryogenic Process and Cryo Storage Solutions from Froilabo

Cryogenic Process and Cryo Storage Solutions from Froilabo

The cryogenic process and cryo storage are ideal solutions for the storage of biological samples and ensuring cell viability over time.Storing a sample under cryogenic conditions requires careful preparation to minimise damage to the sample. Considerations must be taken when deciding how to prepare a ...

ByFroilabo - Techcomp Group


What is a Liquid Nitrogen Storage Tank and What is it Used for?

What is a Liquid Nitrogen Storage Tank and What is it Used for?

When the vessel is used to store samples, such as human or animal tissue, embryos, semen or other biological materials, it is known as cryogenic storage vessel, a liquid nitrogen freezer or a liquid nitrogen storage tank. ...

ByFroilabo - Techcomp Group


Navigating the Bioinformatics Workflow for Whole Exome Sequencing: A Step-by-Step Guide

Navigating the Bioinformatics Workflow for Whole Exome Sequencing: A Step-by-Step Guide

Variant calling is used to identify SNPs and short indels in exome samples. The common variant calling tools are listed in Table 1. Some studies have evaluated these variant callers. ...

ByCD Genomics


Tips & Tricks to Optimize Your Tissue Processing

Tips & Tricks to Optimize Your Tissue Processing

Since the 19th century, the practice of tissue processing has remained largely unchanged, resulting in solidified, paraffin-embedded tissue blocks for sectioning. As staining procedures have advanced and immunohistochemistry is becoming more widely used, high-quality tissue sections are paramount for accurate interpretation of disease ...

ByQuartzy Inc.


QC and product screening of hair, skin, and dentalcare products with NIRS

QC and product screening of hair, skin, and dentalcare products with NIRS

Quality control of hair, skin, and dentalcare products continues to increase in importance for producers. Aside from safeguarding our health, it is equally important to avoid the sale of out-of-specification products. Product recalls are very expensive and have a lasting effect on a company’s reputation. Therefore, intensive testing of these different care products is essential before ...

ByMetrohm AG


Spatial profiling of chromatin accessibility in mouse and human tissues

Spatial profiling of chromatin accessibility in mouse and human tissues

Finally, spatial-ATAC-seq is yet to be further extended to tissue samples from human patients with a disease to realize its full potential in clinical research. ...

ByAtlasXomics Inc.


Eight Commonly Used Techniques for Drug Analysis

Eight Commonly Used Techniques for Drug Analysis

Drug analysis and testing involves the study of composition, physical and chemical properties, purity, and the determination of the content of active pharmaceutical ingredients and their preparations, to ensure that the medications are safe, rational, and effective. ...

ByCD Formulation


CD Genomics Perspective: Bioinformatic Analysis for HLA Genotyping

CD Genomics Perspective: Bioinformatic Analysis for HLA Genotyping

The appropriate bioinformatics approach depends on the sample preparation method and the type of sequencing platform. HLA genotyping bioinformatics solutions are designed to provide reliable, accurate and reproducible results to infer the precise variation in HLAs and to understand the relationship between HLA polymorphisms and the etiopathogenesis of diseases. ...

ByCD Genomics


The Benefits of Using an Automated Pipetting System Over Manual Pipetting

The Benefits of Using an Automated Pipetting System Over Manual Pipetting

Automation now eases manual processes in so many aspects of society, from smart home switches to manufacturing lines. It’s also helping those working in molecular biology, biotech and pharmaceuticals to find new efficiencies and cost savings. So why consider an upgrade from manual pipetting in your lab? ...

ByBio Molecular Systems


Employee Spotlight: Dr. Gerald Martin

Employee Spotlight: Dr. Gerald Martin

My work ranges from processing sample files, preparing example clinical reports, explaining features, listening to customers and prospective customers explain their challenges and issues, and/or helping them overcome challenges to process their patient samples through the platform. ...

ByPierianDx


Thermo Fisher Scientific Launches Collection Kit to Streamline Saliva Testing

Thermo Fisher Scientific Launches Collection Kit to Streamline Saliva Testing

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ByThermo Fisher Scientific, LIMS & Laboratory Software


SARS-CoV-2 (Coronavirus) Detection in Wastewater

SARS-CoV-2 (Coronavirus) Detection in Wastewater

SARS-CoV-2 detection workflow in wastewater Monitoring wastewater for SARS-CoV-2 – or Coronavirus as it is more commonly known – can be a valuable data resource for an effective COVID-19 management. However, there are several challenges involved in detecting biological parameters in wastewater. Fortunately, there are also several solutions available to overcome them. Wastewater ...

ByAnalytik Jena - an EndressHauser Company


Sight Diagnostics raises $71M Series D for its blood analyzer

Sight Diagnostics raises $71M Series D for its blood analyzer

With a founding team that used to work at Mobileye, among other companies, Sight made an early bet on using machine vision to analyze blood samples and provide a full blood count comparable to existing lab tests within minutes. ...

BySight Diagnostics

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