sars-cov-2 Articles
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Viable SARS-CoV-2 Delta variant detected in aerosols in a residential setting with a self-isolating college student with COVID-19
Highlights Viable Delta Variant SARS-CoV-2 collected from air samples in a residential environment. SARS-CoV-2 detected in an area of a single-family dwelling distant from an isolation suite occupied by COVID-19 patient. Assessment of air samples and surface swab samples by rRT-qPCR and cell culture for SARS-CoV-2. Employment of air samplers functioning based on different collection ...
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The Molecular Microbiology of SARS-CoV-2: Detection Methods and Infection Mechanism
SARS-CoV-2 is a newly discovered human coronavirus group (HCoV), which are single-stranded RNA viruses belonging to the family of Coronaviridae. A range of respiratory diseases have been induced by some of these pathogens in the past. SARS-CoV-1 infected more than 8,000 individuals around the world, for example. Human coronavirus linked to Middle East respiratory syndrome (MERS-CoV) also occurred ...
By CD Genomics
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Biocientifica SA develops a new high sensitivity RT-PCR kit for SARS-CoV-2
The Argentinian National Administration of Drugs, Food and Medical Technology (ANMAT) approved New kitfor the qualitative detection of the SARS-CoV-2 virus based on Real-Time RT-PCR technology. The Argentinian National Administration of Drugs, Food and Medical Technology (ANMAT) approved Schep SARS-CoV-2 RT-PCR Duo Biocientfica SA, an Argentinian biotechnology company developed this sensitive in ...
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Microbial Discovery - Case Study
Goal Understanding of Coronavirus (SARS-CoV-2) of interest using whole-genome sequence data from NCBI Solution Loci helps the scientists to understand the Coronavirus at the molecular level with a few click ...
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Low-entry-barrier point-of-care testing of anti-SARS-CoV-2 IgG in the population of Upper Austria from December 2020 until April 2021 - a feasible surveillance startegy for post-pandemic monitoring?
Abstract: The aim of this study was to estimate the prevalence of SARS-CoV-2-specific immunoglobulin G antibodies in the federal state of Upper Austria (Austria) during the period of December 2020 until April 2021. To achieve this goal, we have analyzed anonymized data on the immune status of self-referral volunteers that have been determined at local pharmacies through a low-entry-barrier ...
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AI Designed Mutation Resistant Broad Neutralization Antibodies Against Multiple SARS-CoV-2 Strains based on A Digital Twin of COVID-19 - Case study
Introduction The emerging variants including Delta and Omicron may not retain activity with current available mAb products that were developed during the initial outbreak with the B.l strain. In this study, we have applied AI technologies in the computational design of broad neutralization antibodies against over 1300 different historical SARS-CoV-2 strains with very small computational cost. ...
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SARS-CoV-2 Multi-FAST
We have great news to share: we launched Schep SARS-CoV-2 Multi-FAST, a new PCR diagnostic test for the rapid detection of SARS-CoV-2, now in multiplex and in a single step format! Simple detection, by reverse transcription and Real Time PCR. It consists of a single Master Mix, ready to use, containing the enzymes, primers and probes, specific for 3 viral genes: Envelope (E), Nucleocapsid (N) ...
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Coronavirus Variants: The Delta Variant and the Future Impact of Viral Mutations
If you are fully vaccinated, should you be worried about the impact of COVID-19 variants? No, in fact vaccines have been shown to be highly effective at preventing hospitalizations and deaths from these SARS-CoV-2 variants. While the infamous Delta variant has now been detected in 98 countries and all 50 states, 99% of all COVID-19 deaths and hospitalization cases are unvaccinated, according to ...
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Huateng Pharma Supplies Ensitrelvir Intermeidates Against COVID-19
Ensitrelvir (code name S-217622, brand name Xocova), is a new inhibitor of the SARS-CoV-2 major protease (Mpro), also known as 3C-like protease, has been shown to reduce the viral load and help alleviate the severity of SARS-CoV-2 in infected hamsters. In cells, low nanomolar to sub-micromolar doses of Ensitrelvir suppress viral growth. In hamsters, oral treatment of Ensitrelvir showed excellent ...
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How can Nuvonis help to fight the SARS-CoV-2 pandemics?
At the end of the year 2019, a cluster of severe pneumonia of unknown cause was described in Wuhan (Eastern China) and a SARS-like acute respiratory distress syndrome (ARDS) was noted in these patients. Early in January 2020, sequencing revealed a novel coronavirus (now termed SARS-CoV-2) as the causal factor for the disease designated as COVID-19. The pandemic caused by the virus has unforeseen ...
By Nuvonis
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A year later, there’s still hope!
As we reach our one year anniversary of COVID-19 (or pass it, depending on who’s tracking it), aerosol researchers are still working to convince the world that SARs-CoV-2 is transmitted largely through the air. This is the largest list of eminent experts (363) from around the world, requesting the Canadian officials take the overwhelming evidence seriously and suggest seven key activities ...
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Spring is here - will the coronavirus die in summer?
Spring is fast approaching, and coronavirus restrictions are being lifted all over the northern hemisphere. Are we ready to loosen up protection? Is there hope the virus will die in summer? With time flying unnoticed, we are already into our third summer with coronavirus being part of our lives. As of today, almost 500 million people worldwide have been in contact with SARS-CoV-2. These, of ...
By Respiray OU
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Ozette’s AI in the battle against Covid - Case study
Summary The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic began in 2019 and rapidly scaled to a global presence of disease known as COVID-19. Despite the relatively fast implementation of testing and vaccination worldwide, the rise of emerging viral variants and breakthrough infections raises concerns that SARS-CoV-2 will continue to pose a global health threat. ...
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qPCR for SARS-CoV-2 Detection and Research: Introduction, Principles, and Applications
Introduction to Quantitative Polymerase Chain Reaction A highly delicate technique for the amplification and identification of deoxyribonucleic acid is polymerase chain reaction (PCR). In molecular biology, its conceptual simplification has made it the most utilized method and can, in theory, identify as little as a single segment of DNA. Therefore, for a huge variety of bacterial, fungal, viral, ...
By CD Genomics
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Binding and Inactivating Coronavirus with Clinoptilolite
Natural zeolites are known to bind various bacteria and viruses. Researchers hypothesised that clinoptilolite can also bind members of the Coronaviridae family. Results showed that the addition of 0.01% PCT purified clinoptilolite to a HCoV-229E suspension containing 16,000 PFU per ml resulted in an 87% reduction of the virus concentration. Results suggest that purified clinoptilolite in a ...
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Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2
The recent COVID-19 pandemic again highlighted the urgent need for broad-spectrum antivirals, both for therapeutic use in acute viral infection and for pandemic preparedness in general. The targeting of host cell factors hijacked by viruses during their replication cycle presents one possible strategy for development of broad-spectrum antivirals. By inhibiting the Raf/MEK/ERK signaling pathway, ...
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mRNA vaccine for the pregnant produces antibodies that are passed on to the child and remain for at least 6 months
As the COVID-19 pandemic enters its third year, efforts to mitigate the risk of infection remain critical, especially for vulnerable populations. Recently, Andrea Edlow et al. of Massachusetts General Hospital published a study in the journal JAMA entitled "Durability of Anti-Spike Antibodies in Infants After Maternal COVID-19 Vaccination or Natural Infection". The study showed that ...
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High Throughput SHERLOCK CRISPR SARS-CoV-2 Test
Abstract: The ability to control the spread of COVID-19 has been hampered by a lack of rapid, scalable, and easily deployable diagnostic solutions. Efforts to increase testing capacity have been adversely impacted by supply chain challenges due to dependencies on a limited set of reagents, consumables, and instrumentation. Here, we present a diagnostic method based on CRISPR (clustered regularly ...
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BioSpot-VIVAS sampler used to support COVID aerosol theory
Over the month of August, new research on COVID-19 adds to the likelihood that the SARS-CoV-2 virus can be transmitted through airborne routes. Featured in many news articles around the world, including the New York Times, FOX, CBS and the Daily Mail, Dr. John Lednicky, Research Professor at Environmental and Global Health, University of Florida and his research team, found infectious virus can ...
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Ideal COVID-19 Vaccine May Come from Alpacas, New Study Found
In response to the COVID-19 caused by the new coronavirus (SARS-CoV-2), there are currently many vaccines on the market worldwide. However, despite the fact that major manufacturers are working hard to produce vaccines, the speed of vaccination still cannot keep up with people's needs. At the same time, with the continuous emergence of mutant strains, the effectiveness of vaccines has begun to ...
By Profacgen
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