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Successful Ivf Clinic Articles & Analysis

30 articles found

Comprehensive Disease Models for Preclinical Drug Discovery

Comprehensive Disease Models for Preclinical Drug Discovery

Preclinical drug discovery represents a critical phase in the development of new therapeutics. It is the process that bridges the gap between basic research and clinical testing, allowing for the evaluation of potential drug candidates in biological systems before they are tested in humans. Central to this phase is the use of appropriate disease models, which are essential for understanding the ...

ByCreative Biogene


The Importance of Data Diversity to Enhance Clinical Trials Success

The Importance of Data Diversity to Enhance Clinical Trials Success

Medical advancement relies on clinical trials, which are essential for the development of safe and effective innovative treatments. However, the success and general applicability of these treatments heavily depend on the diversity of the participants involved¹?³. This blog explores the importance of achieving data diversity in clinical trials to enhance clinical trial results and ...

BySOPHiA Genetics


Recent Advances in ADC Linker

Recent Advances in ADC Linker

The development of antibody-drug conjugates (ADCs) has progressed significantly over the past decade due to improvements in payloads, linkers, and conjugation methods. In particular, linker design plays a key role in regulating ADC stability in systemic circulation and payload release efficiency in tumors, thereby affecting ADC pharmacokinetics (PK), efficacy, and toxicity profiles. Some key ...

ByBOC Sciences


ADC Cleavable Linker : Classification and Mechanism of Action

ADC Cleavable Linker : Classification and Mechanism of Action

Antibody-drug conjugates (ADCs), as emerging anticancer drugs, can deliver highly cytotoxic molecules directly to cancer cells to kill them. ADC is a monoclonal antibody covalently bound to cytotoxic chemical substances (payload) through linker. ADC linker plays a key role in the therapeutic effect of ADC, and its characteristics greatly affect the therapeutic index, pharmacodynamics and ...

ByBOC Sciences


Understanding the Importance of Preclinical Animal Models in Drug Development

Understanding the Importance of Preclinical Animal Models in Drug Development

In the world of pharmaceuticals, developing safe and effective drugs is a complex and time-consuming process. Before a new drug candidate can progress to clinical trials and ultimately reach the market, it needs to undergo rigorous testing in various model systems to assess its efficacy and safety. One critical component of this evaluation is the use of preclinical animal models. Preclinical ...

ByCreative Bioarray


Unlocking nature’s secrets? How Nuritas harnesses AI to uncover hidden health-boosting ingredients

Unlocking nature’s secrets? How Nuritas harnesses AI to uncover hidden health-boosting ingredients

Biotech company Nuritas speeds up ingredient discovery in nutrition through AI, using techniques from the pharmaceutical industry where innovation and investment rates are much higher. Through its bioactive peptide finder, Magnifier NπΦ, the company can boast a clinical trial success rate of 80%. Development of an ingredient goes through three phases, from discovery to preclinical biology ...

ByNuritas Ltd.


Meet Nuritas, the bitoech using AI to identify the next generation of intelligent ingredients

Meet Nuritas, the bitoech using AI to identify the next generation of intelligent ingredients

As part of our quick fire questions series – or QFQs – we spoke to Dr. Andy Franklyn-Miller, Chief Medical and Innovation Officer at Nuritas about intelligent ingredients, explaining peptides and proving an AI model in life science. There is a lack of innovation within ingredients in food, many have been discovered decades ago, mostly with cost, taste and texture in mind. However as ...

ByNuritas Ltd.


Immune Strategies for Cancer Treatment

Immune Strategies for Cancer Treatment

In the search for innovative and effective ways to target cancer, we are faced with more than just a challenging problem; we are faced with our own cells as opponents. Cancer cells evolve to achieve an optimum of physical fitness, giving them an array of abilities that no cell should possess in a healthy organism. One way to find novel therapies against cancer therefore could imply finding a ...

Bylino Biotech AG


BeadReadyâ„¢ successfully storing cells for 3D biofabrication

BeadReadyâ„¢ successfully storing cells for 3D biofabrication

Another fantastic publication highlighting one of the multiple applications Atelerix products have within the scientific research and development industry. Anastassia Kostenko , Che J. Connon, and Stephen Swioklo (2023), have successfully shown that Atelerix BeadReady™ is a simple, adaptable solution for room temperature cell storage in combination with biofabrication and how this can be ...

ByAtelerix Ltd


Taking Medical Coding to the next level with AI and Machine Learning

Taking Medical Coding to the next level with AI and Machine Learning

Accuracy in medical coding is a vital aspect in aiding clinical trial operation success. It has presented an excellent opportunity for medical coders, working hand-in-hand with AI-enhanced computer-assisted coding systems, to quickly identify and validate the correct codes. Using natural language processing (NLP) and advanced Machine Learning algorithms, AI is transforming medical coding by ...

ByClinion


Recursion Pharmaceuticals Puts Strength on Full Display

Recursion Pharmaceuticals Puts Strength on Full Display

The drug developer's latest capital raise, a $150 million private placement, comes during a difficult market environment. The strongest companies can raise money in any environment. Recursion Pharmaceuticals (RXRX) - Get Free Report recently raised $150 million in gross proceeds from a private placement of common stock, including half from a single fund that has never before invested in the ...

ByRecursion


Set Up Your Clinical Trial For Success During The Holidays

Set Up Your Clinical Trial For Success During The Holidays

The Holiday season often brings mixed feelings for many. While it can be a time of relaxation with friends and family for some, for others, preparing for this time means ensuring business continuity despite a typical slow down. This can be a source of undue stress if it is not suitably planned for. ...

BySeascape Clinical


Clinical CRISPR Success Demonstrates Need for Quality Control

Clinical CRISPR Success Demonstrates Need for Quality Control

The Clinical CRISPR Successes Are Stacking Up. But Where’s the Emphasis on Quality Control? In mid-September, Intellia released some promising data on two of their CRISPR-based therapeutics. These results are a significant milestone for genome editing and validation of its effectiveness in the clinic. However, the safety of CRISPR-based therapeutics has been a major concern and part of a ...

ByCRISPR QC


The Netflix of Digital Biology? Recursion Is Reimagining Drug Discovery

The Netflix of Digital Biology? Recursion Is Reimagining Drug Discovery

By applying a proprietary operating system to drug discovery, the Utah clinical-stage biotechnology company expects to turn drug discovery from sequential testing into a search problem. Unmet clinical needs often serve as the fundamental driving force behind drug discovery programs. During lead discovery, an intensive search ensues to find a drug-like small molecule or biological therapeutic, ...

ByRecursion


SmartTab Completes Successful Preclinical Animal Studies for TargetTabâ„¢ Platform

SmartTab Completes Successful Preclinical Animal Studies for TargetTabâ„¢ Platform

SmartTab is pioneering a wireless remote controlled drug delivery system, has completed pre-clinical animal studies and is preparing for human clinical trials for its core technology TargetTab™. This proprietary and patented wireless capsule will revolutionize targeted drug delivery and medicine adherence. DENVER, CO — Prescription pills are often delivered to the wrong site, at ...

BySmartTab


Susceptibility of ePTFE vascular grafts and bioengineered human acellular vessels to infection

Susceptibility of ePTFE vascular grafts and bioengineered human acellular vessels to infection

Background: Synthetic expanded polytetrafluorethylene (ePTFE) grafts are routinely used for vascular repair and reconstruction but prone to sustained bacterial infections. Investigational bioengineered human acellular vessels (HAVs) have shown clinical success and may confer lower susceptibility to infection. Here we directly compared the susceptibility of ePTFE grafts and HAV to bacterial ...

ByHumacyte, Inc.


DR Systems and Vidar Partner to Ease the Transition to Digital Mammography - Case Study

DR Systems and Vidar Partner to Ease the Transition to Digital Mammography - Case Study

DR Systems. Inc.. is a leading provider of integrated medical image management systems for hospitals and imaging centers. Co-founded in 1992 by practicing radiologist Murray Reicher, M.D.. the company has become one of the preeminent vendors in the PACS industry and serves facilities of all sizes, ranging from one of the smallest hospitals in the United States to large academic medical centers ...

ByVIDAR Systems Corporation


Q&A with Flyn McKinnirey, R&D Manager at Regeneus

Q&A with Flyn McKinnirey, R&D Manager at Regeneus

Q. What is your background and experience in the regenerative medicine and stem cell space? How did this lead you to Regeneus? A. I’d always had a love for medical research, however found myself working in the pharmaceutical industry after university prior to joining Regeneus. After 6 years in the pharma industry, I’d decided I needed to get back to a research focused career. The ...

ByRegeneus Ltd.


How One Smart MedTech Company is Leveraging Innovation to Save the Lives and Limbs of VTE Patients

How One Smart MedTech Company is Leveraging Innovation to Save the Lives and Limbs of VTE Patients

Medical device start-up companies must focus on innovation, regulatory compliance, efficient processes and prudent financial management in order to survive. Smart MedTech companies prioritize their funding to only support innovation which will result in new products that fulfill significant unmet clinical needs over the long-term. Thrombolex, a relatively new entrant into the MedTech sector, is a ...

ByThrombolex, Inc.


The power of autoantibodies to enhance clinical development success in Systemic Sclerosis (SSc)

The power of autoantibodies to enhance clinical development success in Systemic Sclerosis (SSc)

An unmet need for disease-modifying therapy persists for patients with Systemic Sclerosis SSc is an autoimmune disease characterised by widespread vascular injury, progressive fibrosis of the skin and internal organs, and a specific pattern of autoantibodies. The clinical manifestations of SSc are highly heterogenous with significant internal organ manifestations causing a greater mortality ...

ByOncimmune Holdings PLC

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