Surface Plasmon Resonance Articles & Analysis
11 articles found
Protein-Protein Interaction Studies ELANE is involved in complex interactions with matrix components, cytokines, and plasma inhibitors. Surface plasmon resonance (SPR), co-immunoprecipitation, and biolayer interferometry using recombinant ELANE enable kinetic analysis of these molecular partnerships. 3. ...
Biopanning involves exposing the library to the antigen immobilized on a solid surface, allowing only the bound phages to be eluted and amplified. 4. Characterization After selection, characterized clones are further analyzed for their binding affinity, specificity, and stability. Techniques such as ELISA, surface plasmon ...
At present, recombinant protein drugs are widely used in various fields such as tumors, autoimmune diseases, metabolic diseases, geriatric diseases, and degenerative diseases.FcyR (Fc gamma receptors) are receptors expressed on the surface of immune cells, primarily responsible for recognizing and binding to the Fc (Fragment crystallizable region) part of antibodies. ...
l Surface: The surface of the microarray is typically made of glass or other material that allows for the attachment of glycans in a controlled pattern. The surface must also be capable of efficient sample delivery and detection, ensuring high sensitivity. ...
Techniques such as capillary isoelectric focusing (cIEF) and capillary zone electrophoresis (CZE) are frequently utilized. Nuclear Magnetic Resonance (NMR) Spectroscopy NMR spectroscopy plays a critical role in structural elucidation of ADCs. ...
High-throughput methods for kinetic analysis using surface plasmon resonance (SPR) can quickly analyze the kinetic and affinity characteristics of a series of antibodies, thereby selecting antibodies with different affinities, binding rates, and dissociation rates to enrich the diversity of antibody candidates. ...
Binding Activity Testing(1) Enzyme-Linked Immunosorbent Assay (ELISA)Uses the target antigen coated on microtiter plates to test the binding ability of the antibody drug.(2) Surface Plasmon Resonance (SPR)Can detect the binding between the antibody and the target molecule in real-time, and determine the rate constants for binding and ...
ATA has a variety of research platforms, including bridging ELISA, electrochemiluminescence (ECL), radio immunoprecipitation (RIP), surface plasmon resonance (SPR), etc. Reference Basa, L. (2013). Drug-to-antibody ratio (DAR) and drug load distribution by LC-ESI-MS. ...
X-ray crystallography, nuclear magnetic resonance (NMR), and surface plasmon resonance (SPR) are commonly used techniques for determining the structures and interactions of protein-DNA complexes. ...
INOVIQ (IIQ) signs a contract research agreement with Nicoya Lifesciences to develop a SubB2M-based test that uses its Alto digital surface plasmon resonance (SPR) platform The company believes a SubB2M-based SPR test has the potential to be developed as a multi-cancer detection test that first detects the Neu5Gc cancer signal Under the ...
The researchers selected C1, H3, C5, and F2, the four VHHs with the highest affinity to the receptor binding domain (RBD) of the virus S protein, and produced them, and used surface plasmon resonance (SPR) measurement in a joint competitive binding test. ...