Testing In Animals Articles & Analysis: Older
11 articles found
Moreover, they provide a safer and more ethical alternative to animal testing by enabling in vitro experimentation. One notable application of stable cell lines is in cancer research, where they are used to model tumor behavior and test potential treatments. ...
Most drug failures occur in Phase II and Phase III clinical trials when drugs move from immortalized cell lines and animal testing to human patients. One of the primary reasons for these late-stage failures is that the heterogeneity of human subjects is not introduced until clinical trials are already ...
Quality Control of Aluminum-adjuvanted Vaccines First, the nature of the surface charge of aluminum-adsorbed antigens needs to be understood in order to predict the physical properties of vaccine suspensions; Second, determining the rate and strength of adsorption of aluminum adsorbed antigens can help us to understand the ability of aluminum adjuvants to adsorb antigens, as well as their ...
1. Understanding animal behavior: Animal cognitive behavioral tests help researchers gain insight into how animals think, learn, and solve problems. By conducting cognitive behavioral tests, scientists can better understand the cognitive abilities of different animal species and how they compare ...
Published by Vijay K Singh and Thomas M Seed on September 3, 2021, in Expert Opinion on Drug Discovery and deals with the necessity of animal models for modern drug research in the direction of animal strains, animal models, requirements, and pathways for developing new drugs. ...
In future studies, these six drug candidates may be used in animal tests, such as mice or primates. "We have established a comprehensive network of virus-host protein interactions to identify candidate proteins that can be targets for drug repurposing. ...
One year later, Doug [Brenneman] let me know that his chemists at Neuropathix had synthesized a compound, and asked if I was interested in testing it in an animal model. So, we began a basic screening of KLS-13019, and then received a grant from the National Institute on Drug Abuse in 2019 to initiate the animal study. ...
Both the patients and the drug manufacturer would benefit. Elimination of animal testing also has a societal benefit. There is a strong push in the pharmaceutical industry to reduce and if possible eliminate animal testing for ethical reasons. There is as a result a desire to recapitulate in vivo tests conducted ...
Artificial skin is also a valuable asset to R&D for animal free product testing, toxicity assessments, UV photoaging, cancer biology, and cell growth and communication studies (4). ...
There are now nearly 230 million patients with osteoarthritis in the world and 4 million additional cartilage lesions per year. Osteoarthritis results anatomically in the destruction of cartilage in the joints (knee, hip, etc.), which causes severe pain and a significant reduction in mobility. ACS Biotech is an innovative biotechnology company created in 2013 by Pascale Hazot, Doctor of ...
It is caused by an abnormally folded protein called a prion. The prion protein infects the animal by promoting conversion of normal cellular protein to the abnormal form. It affects the neurological system of the animal such as lymph nodes, spinal column and neural tissues, including the brain. ...