The Study Of Liver Diseases Aasld The Liver Articles & Analysis
41 articles found
Non-alcoholic fatty liver disease (NAFLD) has emerged as a significant public health concern, associated with obesity, insulin resistance, and a spectrum of metabolic disorders. Understanding this condition is crucial for effective intervention and treatment. Preclinical models are indispensable for advancing our knowledge of NAFLD, as they provide the necessary platforms to study its ...
Cyanotoxins are toxic substances produced by cyanobacteria, or blue-green algae, which can proliferate in water bodies under conditions like high nutrient levels and warm temperatures. There are over 1,118 different cyanotoxins identified globally in freshwater environments across 66 countries, illustrating the widespread nature of this ...
Bile, a complex fluid produced by the liver and stored in the gallbladder, plays a crucial role in the digestion and absorption of fats, fat-soluble vitamins, and other essential nutrients. Ox bile extract powder, derived from the bile of oxen, is a natural supplement that has garnered significant interest in the scientific and healthcare communities for its versatile physiological functions and ...
Trillions of microorganisms live in the gastrointestinal tract, far outnumbering the body's own cells. The intestinal flora is involved in many physiological and pathological processes in the host, including digestion and absorption of food, metabolism of certain nutrients and pharmaceutical compounds, development of host immunity, intestinal inflammatory states, and more. Dysbiosis of the ...
Bile acids are synthesized in the liver from cholesterol as a raw material. As a natural "emulsifier", they can promote the dissolution, digestion and absorption of fats, fat-soluble vitamins, etc. Meanwhile, as an important signaling molecule, bile acids can activate the relevant receptors to maintain the homeostasis of hepatic glucose and lipid metabolism, and interact with gut bacteria to ...
siRNA, with a molecular weight of about 13 kDa, recruits the RNA-induced silencing complex (RISC) to mRNA through base pairing, thereby inhibiting protein translation. The mRNA is targeted for cleavage through the catalysis of the RISC protein Ago2, a member of the Argonaute family. In addition, other Ago proteins (Ago1, Ago3, and Ago4) catalyze endonuclease-mediated degradation of non-specific ...
AMPK (Adenosine 5'-monophosphate (AMP)-activated protein kinase), as an important kinase regulating energy homeostasis, is one of the central regulators of eukaryotic cell and organism metabolism. It is responsible for regulating cellular capacity input and output and maintaining the smooth functioning of cellular physiological activities. AMPK is also a key protein involved in various signaling ...
Vaccines are considered one of the most successful medical interventions in the past few centuries, aiming to harness the human immune system and generate lasting protection against specific diseases. Traditional vaccines rely on the use of inactivated pathogens to trigger an immune response. However, many of these formulations carry a high risk of causing allergies or autoimmune reactions. ...
In the vibrant realm of cellular biology and regenerative medicine, mesenchymal stem cells (MSCs) hold unparalleled potential for therapeutic applications. Particularly noteworthy are bone marrow mesenchymal stem cells (BM-MSCs), a subtype of MSCs. Their unique properties make them indispensable resources for developing ground-breaking solutions for various medical conditions. Mesenchymal stem ...
Introduction to OsteoporosisOsteoporosis is a systemic multi-causal skeletal disease that is prone to fractures due to changes in systemic bone mass and microstructure of bone tissue, resulting in increased bone fragility. Osteoporosis is a type of disease that is difficult to cure. According to the etiology, it can be divided into primary osteoporosis, secondary osteoporosis and idiopathic ...
Enzymes are protein molecules that catalyze chemical reactions in living organisms. They are involved in many metabolic processes and play a critical role in maintaining the health of the body. In recent years, enzymes have been widely used in disease diagnosis, providing a quick and accurate way to detect and monitor diseases. Enzymes for disease diagnosis can be divided into two categories: ...
Correct fresh frozen plasma storage is vital for safe and efficient treatment of patients with blood clotting disorders in various situations.This article will explore fresh frozen plasma preparation, storage and uses and discuss the Froilabo products that can aid your fresh frozen plasma storage.Fresh Frozen Plasma PreparationPlasma is the liquid portion of whole blood. It contains many ...
Enzymes are biological catalysts that accelerate chemical reactions in living organisms. In recent years, enzymes have been increasingly utilized in medical diagnostics, leading to significant advancements in disease detection and management. Enzyme-based diagnostic tools have revolutionized the healthcare industry, offering numerous benefits such as increased accuracy, sensitivity, and speed. ...
Canagliflozin is a medication used to treat type 2 diabetes. It is a third-line medication to be tried after metformin, a first-line medication for type 2 diabetes. It is used together with exercise and diet. It is not recommended in type 1 diabetes. Mechanism action of Canagliflozin Canagliflozin is a sodium-glucose cotransporter (SGLT2) inhibitor. Glucose filtered in the renal tubular lumen is ...
Biliary disease is a term used to describe diseases that affect the biliary system, which can result in inflammation, fibrosis, bile duct destruction, and eventually liver failure. It also frequently leads to secondary infections and chronic irritation, such as bile duct stones, which can lead to malignant tumors. There is currently no cure for biliary tract diseases other than liver ...
Purpose Dysregulations of key signaling pathways in metabolic syndrome are multifactorial, eventually leading to cardiovascular events. Hyperglycemia in conjunction with dyslipidemia induces insulin resistance and provokes release of proinflammatory cytokines resulting in chronic inflammation, accelerated lipid peroxidation with further development of atherosclerotic alterations and diabetes. We ...
In medicine, taking a holistic approach means treating the whole person - body, mind, spirit, and emotions - to achieve one’s optimal health and wellness. For example, if a patient comes in with a sharp, jabbing pain in his hand - a symptom of peripheral neuropathy - a holistic treatment plan may not only include pain relief medicine but also address underlying causes of pain. A holistic ...
Situated at the right hand part of your abdominal cavity, liver is the largest organ of your body. This dark brown organ weighs around 1.2 kg. You should know that all the blood which leaves from stomach and your intestine passes through this organ. Liver is solely responsible for carrying away waste products from your blood. Liver is important in your body for a number of reasons, such as, it ...
No parent wants to hear their child has a condition that might affect their education, family life, and overall well-being. Unfortunately, there’s currently no restorative treatment for short bowel syndrome (SBS). Monitoring nutrition is a lifelong necessity for anyone with this disorder. This means that no matter the cause of SBS, there are certain things you should know about nutrition ...
If you go to a doctor regularly, and you should, more than likely you have had your blood tested for sugar levels. A high blood sugar or glucose level can be an indicator for the onset of prediabetes or diabetes. Too much sugar for anyone of any age can be dangerous. But what if you have low blood glucose levels or hypoglycemia? Whether you have diabetes or not low blood sugar levels can be ...