Thyroid Hormones And Thyroid Hormone Articles & Analysis
14 articles found
Although snoring is usually considered as a harmless annoyance, it is actually a symptom of deeper health issues, such as hypothyroidism. This is when the thyroid reduces the production of thyroid, a vital hormone and there is a deficiency in the body. Though the connection between hypothyroidism and snoring isn’t obvious, there have been ...
Anorexia, a condition characterized by a significant reduction in food intake despite negative energy balance, poses severe risks to health and quality of life. It manifests in various forms in humans, including anorexia nervosa and physiological anorexia. While psychological and social factors have been widely studied, the physiological causes remain less understood. For ground squirrels, ...
Introduction of TSH The Thyroid-Stimulating Hormone (TSH) protein is a crucial player in the regulation of thyroid function. ...
Related Link: The Daily Biotech Pulse: Erytech Jumps On Fast Track Designation, GlaxoSmithKline FDA Nod, Alnylam's Clinical Collaboration, 4 IPOs Rani's Pipeline: Rani has a candidate codenamed RT-10 in Phase 1 development for acromegaly, a hormonal disorder. The company has five preclinical compounds evaluated for different indications. ...
Polybrominated diphenyl ethers (PBDEs) and their metabolites (e.g. hydroxylated BDEs (OH‐BDEs)) are contaminants detected together frequently in human tissues, and are structurally similar to thyroid hormones (TH). THs partially mediate metamorphic transitions between life stages in zebrafish, making this a critical developmental window which may be vulnerable ...
Several PBDE congeners are considered thyroid disruptors however avian studies are limited. Here, we examined circulating thyroid hormones, thyroid gland function of nestling American kestrels (Falco sparverius) at 17‐20 d of age, following embryonic exposure by maternal transfer only to environmentally relevant levels of PBDEs ...
In the present study, BPS was injected into the air cell of unincubated, fertilized chicken embryos at 6 concentrations ranging from 0 to 207 µg/g egg to determine effects on pipping success, development, hepatic mRNA expression, thyroid hormone levels, and circulating bile acid concentrations. BPS concentrations increased in a dose‐dependent manner in whole ...
Adult female mink and a subsequent F1 generation were exposed to Aroclor 1268 through diet, and effects on enzyme induction, histopathology, thyroid hormone regulation, hematology, organ weights, and body condition index were compared to a negative control and a 3,3',4,4',5‐pentachlorobiphenyl (PCB 126) positive control. ...
Microcystin‐LR (MC‐LR) has the potential to disturb thyroid hormone (TH) homeostasis, but little is known of the underlying mechanisms of MC‐LR in fish. ...
In contrast, the PPCP mixture down‐regulated vtg in females and males, and expression of erα (estrogen receptor alpha), star, and thra1 (thyroid hormone receptor alpha 1) in testes. Our results show the molecular ‘estrogenic’ effects of triclocarban are eliminated (males) or reversed (females) when dosed in conjunction with several other PPCPs, once again showing ...
The effects of PCP exposure on plasma thyroid hormone levels, and the expression levels of selected genes, were measured in the brain and liver. ...
Reporter gene assays were used to detect receptor‐mediated (anti‐)estrogenic, (anti‐)androgenic, and (anti‐)thyroid hormone activities. The effect of PFOS on steroidogenesis was assessed both at hormone levels in the supernatant and at expression levels of hormone‐induced genes in the H295R cell. ...
Genes involved in the transsulfuration pathway, iron transport and storage, thyroid‐hormone related processes, and cellular respiration were identified by suppression subtractive hybridization as differentially expressed. ...
EDSTAC, which consisted of representatives from diverse stakeholder groups, was charged with providing advice and recommendations to EPA regarding a strategy for determining whether chemical substances may have an effect on humans similar to effects produced by naturally occurring hormones. EDSTAC began its deliberations in October 1996 and completed them in July 1998. The ...