tissue regeneration biomaterial Articles
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Induction of adipose tissue regeneration by chemically-modified hyaluronic acid
Hyaluronan was modified by amidation of the carboxyl groups with dodycyl amides to produce a viscous gel (HYADD3). Small aliquots were implanted intramuscularly in Wistar rats at a concentration of 30 mg/ml for up to 12 weeks. Standard histology and immunohistochemistry demonstrated low levels of inflammation at all time periods, absence of any fibrous capsule coupled with the presence of mature ...
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Hydrothermal synthesis of coccolith rich chalk to hydroxyapatite
Calcium carbonates originating from marine sources show unique pore structure and nano–architecture, offering potential in the field of hard tissue engineering. It is hypothesised that the use of naturally–sourced raw materials for the synthesis of hydroxyapatite (HA), as a component of a hard tissue constructs, enables enhanced bone remodelling due to the biomimetic physical–chemical ...
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Electrospun nanofibres of polycaprolactone, and their use for tendon regeneration
Inferior scar tissue formed when injured tendons heal often results in ongoing pain and site morbidity. With current treatments being ineffective, there is a clinical need for a tissue engineered approach. Electrospinning produces nanofibres with morphologies and architectures similar to the natural extra cellular matrix. Research incorporating electrospinning for tendon regeneration is limited. ...
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